Semaphorin 3A Shifts Adipose Mesenchymal Stem Cells towards Osteogenic Phenotype and Promotes Bone Regeneration In Vivo by Xiangwei Liu, Naiwen Tan, Yuchao Zhou, Xueying Zhou, Hui Chen, Hongbo Wei, Ji Chen, Xiaoru Xu, Sijia Zhang, Guodong Yang, Yingliang Song

“…Furthermore, Sema3A modified ASCs were then engrafted into poly(lactic-co-glycolic acid) (PLGA) scaffolds to repair the critical-sized calvarial defects in rat model. …”
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Effect of non-contact induction heating on HA coatings and bone cement, an ex vivo study [version 2; peer review: 2 approved, 1 approved with reservations] by Robert Kamphof, Dr. Bart G.C.W. Pijls, Dr. Rob G.H.H. Nelissen, Jeroen Mesman-Vergeer, Dr. Giuseppe Cama

“…This study aims to provide insight into the feasibility of using non-contact induction heating on metallic implants that are in direct contact with other biomaterials, such as coatings composed of hydroxyapatite and bone cement composed of poly (methyl methacrylate) (PMMA). Methods Characterisation of hydroxyapatite coatings and adhesion strength tests were conducted according to standards set by the International Organisation for Standardisation (ISO 13779-2). …”
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Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study by Atanu Ghorai, Nitai P. Bhattacharyya, Asitikantha Sarma, Utpal Ghosh

“…Cancer treatment with high LET heavy ion beam, especially, carbon ion beam (12C), is becoming very popular over conventional radiotherapy like low LET gamma or X-ray. Combination of Poly(ADP-ribose) polymerase (PARP) inhibitor with xenotoxic drugs or conventional radiation (gamma or X-ray) is the newer approach for cancer therapy. …”
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ITO-Free Semitransparent Organic Solar Cells Based on Silver Thin Film Electrodes by Zhizhe Wang, Chunfu Zhang, Dazheng Chen, Shi Tang, Jincheng Zhang, Li Sun, Ting Heng, Yue Hao

“…ITO-free semitransparent organic solar cells (OSCs) based on MoO3/Ag anodes with poly(3-hexylthiophene) and [6,6]-phenyl-C61-butyric acid methyl ester films as the active layer are investigated in this work. …”
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Efficient Inverted ITO-Free Organic Solar Cells Based on Transparent Silver Electrode with Aqueous Solution-Processed ZnO Interlayer by Zhizhe Wang, Dazheng Chen, Chunfu Zhang, Zhenhua Lin, Yan Liu, Genquan Han, Jingjing Chang, Jincheng Zhang, Lixin Guo, Yue Hao

“…The blend of low bandgap poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b′]dithiophene-2,6-diyl][3-fluoro-2-[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]] (PTB7) and [6,6]-phenyl-C71-butyric acid methylester (PC71BM) is employed as the photoactive layer here. …”
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Magnesium Oxide Nanoparticles Reinforced Electrospun Alginate-Based Nanofibrous Scaffolds with Improved Physical Properties by R. T. De Silva, M. M. M. G. P. G. Mantilaka, K. L. Goh, S. P. Ratnayake, G. A. J. Amaratunga, K. M. Nalin de Silva

“…Alginate-based nanofibres were electrospun from an alginate/poly(vinyl alcohol) (PVA) polyelectrolyte complex. …”
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Assessment of different enrichment methods revealed the optimal approach to identify bovine circRnas by Yixin Wang, Jian Wang, Robert J. Gruninger, Tim A. McAllister, Mingzhou Li, Le Luo Guan

“…In this study, we assessed the outcomes of bovine circRNA identification using six enrichment approaches with the combination of ribosomal RNAs removal (Ribo); linear RNAs degradation (R); linear RNAs and RNAs with structured 3′ ends degradation (RTP); ribosomal RNAs coupled with linear RNAs elimination (Ribo-R); ribosomal RNA, linear RNAs and RNAs with poly (A) tailing elimination (Ribo-RP); and ribosomal RNA, linear RNAs and RNAs with structured 3′ ends elimination (Ribo-RTP), respectively. …”
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Flux Synthesis of A‐site Disordered Perovskite La0.5M0.5TiO3 (M═Li, Na, K) Nanorods Tailored for Solid Composite Electrolytes by Tao Wang, Jiyoung Ock, X. Chelsea Chen, Fan Wang, Meijia Li, Matthew S. Chambers, Gabriel M. Veith, Lauren B. Shepard, Susan B. Sinnott, Albina Borisevich, Miaofang Chi, Amit Bhattacharya, Raphaële J. Clément, Alexei P Sokolov, Sheng Dai

“…SCEs compositing the Li+‐conducting LMTO nanorods as fillers and poly[vinylene carbonate‐co‐lithium sulfonyl(trifluoromethane sulfonyl)imide methacrylate] matrix exhibit more than twice the conductivity of the neat polymer electrolyte (30.6 vs 14.0 µS cm−1 at 303 K).…”
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Superior energy storage capacity of polymer-based bilayer composites by introducing 2D ferroelectric micro-sheets by Zhenhao Fan, Jian Dai, Yuyan Huang, Hang Xie, Yitao Jiao, Wenfeng Yue, Fu Huang, Yuqun Deng, Dawei Wang, Qingfeng Zhang, Yunfei Chang

“…Excitingly, an ultra-high discharged energy density of 25.0 J cm−3 and a large efficiency of 81.2% are achieved in Na0.5Bi4.5Ti4O15-poly(vinylidene fluoride-co-hexafluoropropylene)/Na0.5Bi4.5Ti4O15-polyetherimide bilayer composites under a dramatically enhanced breakdown strength of 8283 kV cm−1. …”
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Interactions between and Shared Molecular Mechanisms of Diabetic Peripheral Neuropathy and Obstructive Sleep Apnea in Type 2 Diabetes Patients by Hong Shen, Junrong Zhao, Ying Liu, Guangdong Sun

“…Numerous molecular mechanisms have been documented that underlie diabetic peripheral neuropathy and OSA, including oxidative stress, inflammation, endothelin-1, vascular endothelial growth factor (VEGF), accumulation of advanced glycation end products, protein kinase C (PKC) signaling, poly ADP ribose polymerase (PARP), nitrosative stress, plasminogen activator inhibitor-1, and vitamin D deficiency. …”
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Relaxin inhibits 177Lu-EDTMP associated cell death in osteosarcoma cells through notch-1 pathway by Xu Junhua, Wan Song, Chen Wei, Zhang Yi, Ji Zhenzhong

“…Western blotting was used to determine expression levels of apoptotic-related signalling pathway proteins like bcl2, poly(ADP-ribose) polymerase (PARP), and MAPK (mitogen-activated protein kinase). …”
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Development of Prevascularized Synthetic Block Graft for Maxillofacial Reconstruction by Borvornwut Buranawat, Abeer Shaalan, Devy F. Garna, Lucy Di Silvio

“…The scaffold, fabricated using sintered monocalcium phosphate with poly (vinyl alcohol) as a porogen, exhibited pore sizes ranging from 0 to 400 μm, with the highest frequency between 80 and 100 μm. …”
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An Enhanced Drought-Tolerant Method Using SA-Loaded PAMPS Polymer Materials Applied on Tobacco Pelleted Seeds by Yajing Guan, Huawei Cui, Wenguang Ma, Yunye Zheng, Yixin Tian, Jin Hu

“…Present study was undertaken to create novel drought-resistant pelleted seeds using the combined materials with superabsorbent polymer, poly(2-acrylamide-2-methyl propane sulfonic acid) (PAMPS) hydrogel, and drought resistance agent, salicylic acid (SA). …”
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Comparative Study of Crucial Properties of Packaging Based on Polylactide and Selected Essential Oils by Ewa Olewnik-Kruszkowska, Astha Vishwakarma, Magdalena Wrona, Anis Bertella, Anna Rudawska, Magdalena Gierszewska, Beata Schmidt

“…In order to establish the differences in packaging containing various essential oils, polylactide (PLA)-based polymeric films incorporating poly(ethylene glycol) (PEG), clove (C), grapefruit (G), rosemary (R), and tea tree (T) essential oils were obtained and subsequently analyzed. …”
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PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…In this study, we took a deliberate approach devoid of any chemical alterations to develop a novel photosensitizer called “pharmaceutical-dots (pharm-dots)” by combining nonemissive polymers (Poly (lactic-co-glycolic acid), PLGA) with nonfluorescent invisible molecules like curcumin, berberine, oridonin into PLGA nanoparticles (PLGA-NPs). …”
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Profiling Pro‐Inflammatory Proteases as Biomolecular Signatures of Material‐Induced Subcutaneous Host Response in Immuno‐Competent Mice by Nam M.P. Tran, Anh T.H. Truong, Dang T. Nguyen, Tram T. Dang

“…Quantitative non‐invasive monitoring with activatable fluorescent probes reveals that different microparticulate materials induce distinct levels of protease activity with degradable poly(lactic‐co‐glycolic) acid inducing the strongest signal compared to nondegradable materials such as polystyrene and silica oxide. …”
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Fabrication of Core-Shell PEI/pBMP2-PLGA Electrospun Scaffold for Gene Delivery to Periodontal Ligament Stem Cells by Qiao Xie, Lie-ni Jia, Hong-yu Xu, Xiang-gang Hu, Wei Wang, Jun Jia

“…In this study, the bioactive PEI (polyethylenimine)/pBMP2- (bone morphogenetic protein-2 plasmid-) PLGA (poly(D, L-lactic-co-glycolic acid)) core-shell scaffolds were prepared using coaxial electrospinning for a controlled gene delivery to hPDLSCs (human periodontal ligament stem cells). …”
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Identification of the Genomics and Transcriptomics Regulators of the DNA Damage Response in Breast Cancer by Mehdi Sadeghi, Mohammad Reza Karimi, Amir Hossein Karimi

“…In recent years, the clinical utilization of a class of drugs called poly (ADP-ribose) polymerase inhibitors has been observed to be detrimental to cells that harbor defective DNA damage repair mechanisms. …”
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Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products by Rucha Wadapurkar, Swarda Deo, Renuka Khanzode, Ajay Singh

“…We determined the sequence identity, DNA and RNA contamination, off-target RNA contamination, and poly-A count with the proposed workflow. <b>Results</b>: Our workflow predicted most of the critical quality controls of mRNA vaccine and plasmid DNA samples, especially focusing on the identity and the nucleotide-based impurities. …”
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Expression of genes of cytokines, transcription factors and differentiation antigens in human dendritic cells activated by double-stranded DNA by A. S. Proskurina, K. E. Orishchenko, E. A. Potter, E. V. Dolgova, A. V. Spaselnikova, G. S. Ritter, N. A. Varaksin, T. G. Ryabicheva, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, S. S. Bogachev

“…It was found that the preparation of double-stranded DNA transfected by Lipofectamine 2000 boosts DCs at the same level as Poly(dA : dT), a synthetic equivalent of double-stranded DNA. …”
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