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761
PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells
Published 2025-01-01“…Here, we screened for DNA damage response inhibitors that enhance ATRi-induced cytotoxicity using SWI/SNF complex-deficient cells and identified a potent synergy between ATRi and poly(ADP-ribose) polymerase inhibitor (PARPi), particularly in SMARCA4-deficient cells. …”
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762
ZFP36 Regulates Vascular Smooth Muscle Contraction and Maintains Blood Pressure
Published 2025-01-01“…In cultured vascular smooth muscle cell (VSMC), angiotensin II (AngII) activates poly (ADP‐ribose) polymerases1 (PARP1) to stimulate Zfp36 expression at the transcriptional level. …”
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763
Polymer Gels Based on PAMAM Dendrimers Functionalized with Caffeic Acid for Wound-Healing Applications
Published 2025-01-01“…One of these is functionalization with dendrimers, such as the poly(amidoamine) (PAMAM) family. To evaluate the effectiveness of functionalizing caffeic acid with PAMAM dendrimers, the in vitro and in vivo wound-healing properties of gel-PAMAM G3 conjugated with caffeic acid (GPG3Ca) and its precursor, cinnamic acid (GPG3Cin), were studied. …”
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764
Meso-Experimental Study on Tensile Characteristics of Clay
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765
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766
Studies of biofilms and phenotypic characteristics of Candida fungi
Published 2020-06-01“…Formation of mono-species or poly-species biofilms of microorganisms, including Candida spp., causes the development of superficial, deep and systemic candidiasis. …”
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767
Feasibility and Limits of Magnetically Labeling Primary Cultured Rat T Cells with Ferumoxides Coupled with Commonly Used Transfection Agents
Published 2006-04-01“…The best results were achieved by using polyamine TAs and in particular by using poly- l -lysine at a concentration of 1.5 µg/mL administered in combination with 22.5 µg iron/mL. …”
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768
Quantum complexity phase transitions in monitored random circuits
Published 2025-02-01“…Above, the complexity does not exceed $\operatorname{poly}(n)$. In our proof, we make use of percolation theory to find paths along which an exponentially long quantum computation can be run below the critical rate, and to identify events where the state complexity is reset to zero above the critical rate. …”
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769
Laboratory wastewater treatment: Study case of Environmental Engineering Department ITS
Published 2025-01-01“…The fluctuation of wastewater quality and quantity was observed consecutively for two weeks. Aluminum sulfate, poly aluminum chloride, and ferric chloride coagulant were applied with a pH variation, namely 6, 7, and 8, and a variation in coagulant dosage, namely 100, 300, and 500 mg/L. …”
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770
Quantum complexity of time evolution with chaotic Hamiltonians
Published 2020-01-01“…Our analysis relates complexity to familiar properties of physical theories like their spectra and the structure of energy eigenstates and has implications for the hypothesized computational complexity class separations PSPACE BQP/poly and PSPACE BQSUBEXP/subexp, and the “fast-forwarding” of quantum Hamiltonians.…”
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771
Manufacturing and characterization of conductive threads based on twisting process for applying smartwear
Published 2025-02-01“…Abstract A basic study was conducted to manufacture conductive composite threads for use in textile-type electrodes and circuits for smartwear that can be sewn, embroidered, and knitted. The two-types of poly(ethylene terephthalate(PET) filament with a circular cross-section(SD), and an oval cross-section and curved surface(DT), and the conductive yarn was selected as a silver-coated polyamide(AP). …”
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772
Simulation and analysis of ZnO/SWCNT solar cell using the SCAPS-1D program
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773
Piperazine sulfonamides as DPP-IV inhibitors: Synthesis, induced-fit docking and in vitro biological evaluation
Published 2021-12-01“…Dipeptidyl peptidase-IV (DPP-IV) inhibitors minimize glucagon and blood glucose levels by increasing the incretin levels, glucagon-like peptide (GLP-1) and glucose-dependent insulinotropic poly-peptide (GIP), leading to insulin secretion from pancreatic beta cells. …”
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774
Enhancement of Liver Targetability through Statistical Optimization and Surface Modification of Biodegradable Nanocapsules Loaded with Lamivudine
Published 2023-01-01“…Nanocapsules were prepared in this study as aqueous-core nanocapsules (ACNs) with poly(lactide-co-glycolide) using a modified multiple emulsion technique. …”
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775
A Flexible Framework Integrating Digital and Social Competences in Vocational Education Across Diverse Contexts
Published 2025-01-01“…After conducting a literature review and a needs assessment of VET teachers and learners, a flexible three-domain framework is presented, with pathways and training methods that account for the so-called poly-contextual skills that combine digital and social skills. …”
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776
Within Satisfaction and Distress: Characterizing the First Cultural Transition of Young Talented Cameroonian Footballers
Published 2025-01-01“…Naturalistic inquiry. Sage. Poli, R., Ravenel, L., & Besson, R. (2024, May). …”
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777
Exogenous dsRNA triggers sequence-specific RNAi and fungal stress responses to control Magnaporthe oryzae in Brachypodium distachyon
Published 2025-01-01“…Accordingly, the synthetic dsRNA analogue poly(I:C) and dsRNA of various sizes and sequences elicited canonical fungal stress pathways, including nuclear accumulation of the stress marker mitogen-activated protein kinase Hog1p and production of ROS. …”
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778
Escenario económico postconvertibilidad: sus evidencias en la estructura empresaria neuquina
Published 2019-06-01“…Desde mediados de los años 80 y a lo largo de los 90, las actividades económicas de las distintas regiones, tanto como las PyMEs, han ganado una creciente presencia, tanto en los medios académicos como en los espacios donde se formulan políticas y programas, siendo consideradas elementos fundamentales para enfrentar los desafíos del desarrollo en la economía mundial y nacional. …”
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779
Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells
Published 2015-01-01“…Therefore, we examined whether electroporation of mRNA with a proper cap and a poly-A tail of at least 64 adenosines had any influence on cocktail-matured moDCs. …”
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780
PARP‐1 Inhibition Increases Oxidative Stress in Ets‐1‐Expressing MDA‐MB‐231 Breast Cancer Cells
Published 2025-01-01“…In a previous study, we revealed that poly(ADP‐ribose) polymerase‐1 (PARP‐1) inhibition by PJ‐34 results in Ets‐1 level increase in cells, which is related with cell death of Ets‐1‐expressing cancer cells. …”
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