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141
Prospects of oral anticoagulant therapy in patients with atrial fibrillation and chronic anemia: a narrative review
Published 2024-12-01“…Anticoagulant therapy for atrial fibrillation (AF) plays an important role in preventing thromboembolic events. …”
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142
Physical Therapy in the Management of Pelvic Floor Muscles Hypertonia in a Woman with Hereditary Spastic Paraplegia
Published 2014-01-01“…PF spasticity can lead to severe disability and interfere with daily basic functions, such as micturition and evacuation. Physical therapy plays an essential role in the management of these patients and can lead to significant improvement in quality of life.…”
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143
Effect of Motorized Elephant-Assisted Therapy Program on Balance Control of Children with Autism Spectrum Disorder
Published 2019-01-01“…The purpose of this study was to create the motorized elephant-assisted therapy program (METP) and examine the effect of the METP on balance control improvement in individuals with ASD. …”
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144
Design of an Incremental Music Teaching and Assisted Therapy System Based on Artificial Intelligence Attention Mechanism
Published 2022-01-01“…With the continuous updating and advancement of artificial intelligence technology, it gradually begins to shine in various industries, especially playing an increasingly important role in incremental music teaching and assisted therapy systems. …”
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145
Behavioral and Physiological Responses of Therapy Dogs to Animal-Assisted Treatment in an Inpatient Stroke Rehabilitation Program
Published 2025-01-01“…These therapy dog–handler pairs actively participated in stroke rehabilitation by walking with the patient, playing fetch with the patient, and being petted/brushed by the patient, amongst various other AAT activities. …”
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146
Effects of levothyroxine therapy on bone and mineral metabolism in hypothyroidism: a systematic review and meta-analysis
Published 2025-01-01“…Abstract Background Thyroid hormone plays an important role in accumulating bone development and regulating bone metabolism. …”
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147
Menopausal Hormone Therapy: Its Role in the Prevention of Cardiovascular Diseases and the Risk of Breast Cancer in Women
Published 2025-01-01“…However, estrogen metabolism plays a crucial role in the genotoxic pathway that leads to breast cancer. …”
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148
Feasibility and Safety of Perilla Seed Oil as an Additional Antioxidative Therapy in Patients with Mild to Moderate Dementia
Published 2018-01-01“…Dementia is a broad-spectrum terminology for a degenerate in cognitive function severe enough to intervene in activities of daily living. Oxidative stress plays a major role in the neurodegenerative cascade, leading to the irreversible mechanism in dementia. …”
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Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy
Published 2025-02-01“…Robust in vitro and in vivo data demonstrate the efficacy of this approach and CaO2@ZIF8:CUR@PAA as an anticancer platform, paving the way for nanomaterials in immune-triggered cancer therapy.Highlights: - A new calcium accumulation nanoplatform plays a role in activate antitumor immunity.- Double-locked structure slows down the premature decomposition of CaO2.- The platform allows Ca2+ and H2O2 to accumulate in tumor cells.- This leads to mitochondrial dysfunction, apoptosis, and M1 macrophage polarization.- Potent anti-tumor effects are seen both in vitro and in vivo.Keywords: Calcium ion load, controlled-release nanomaterials, two-layer protective shell, pH responsive drug release, reactive oxygen species, anti-cancer…”
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151
Treatment Choices for Tenosynovial Giant Cell Tumor: Surgery or Observation?
Published 2025-01-01“…Imaging examinations and patient-reported outcome tools play a crucial role in evaluating efficacy and guiding treatment decisions. …”
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152
Creative Problem Solving and Social Cooperation of Effective Physical Therapy Practice: A Pioneer Study and Overview
Published 2003-01-01“…Action research (AR) has an important role to play in educating physical therapists. Increasing efforts should be encouraged to instigate AR programs in physical therapy practice and clinical education. …”
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153
Hopf Bifurcation on a Cancer Therapy Model by Oncolytic Virus Involving the Malignancy Effect and Therapeutic Efficacy
Published 2020-01-01“…There are two important parameters in our model that represent the malignancy level of the cancer cells and the efficacy of the therapy. The parameters play an important role to determine the possibility to have successful therapy for cancer. …”
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154
Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy
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Oral Tolerance: A New Tool for the Treatment of Gastrointestinal Inflammatory Disorders and Liver-Directed Gene Therapy
Published 1999-01-01“…The use of oral tolerance toward adenoviruses and colitis-extracted proteins for long term gene therapy and alleviation of experimental colitis, and the mechanisms of tolerance induction are presented. …”
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157
TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies
Published 2025-01-01“…Therapy resistance still constitutes a common hurdle in the treatment of many human cancers and is a major reason for treatment failure and patient relapse, concomitantly with a dismal prognosis. …”
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158
Combination Therapy with GABA and MgSO4 Improves Insulin Sensitivity in Type 2 Diabetic Rat
Published 2022-01-01“…Gamma-aminobutyric acid (GABA) and magnesium sulfate (MgSO4) play a crucial role in glycemic control. Therefore, we studied the effect of combination therapy with GABA and MgSO4 to improve insulin sensitivity in diabetes induced by streptozotocin as well as high-fat diet in a diabetic rat model. …”
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159
Oxidative stress and reactive oxygen species in otorhinolaryngological diseases: insights from pathophysiology to targeted antioxidant therapies
Published 2025-12-01“…Mitochondria, as the primary site of cellular energy production, play a crucial role in modulating oxidative stress. …”
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160
Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT)
Published 2025-02-01“…Abstract Photodynamic therapy (PDT) is a minimally invasive treatment approved for many types of cancers. …”
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