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Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy
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Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy
Published 2025-01-01“…Among the mechanisms safeguarding genomic stability, the Base Excision Repair (BER) pathway plays a pivotal role in counteracting oxidative DNA damage caused by reactive oxygen species. …”
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Enhancing PDAC therapy: Decitabine-olaparib synergy targets KRAS-dependent tumors
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106
Role of Fcγ receptors in HER2-targeted breast cancer therapy
Published 2022-01-01“…Activating FcγRIIIa (CD16A) on natural killer cells plays a crucial role in mediating ADCC, and activating FcγRIIa (CD32A) and FcγRIIIa on macrophages are important for mediating ADCP. …”
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Application of Light-Responsive Nanomaterials in Bone Tissue Engineering
Published 2025-01-01“…Through photothermal and photodynamic therapy, these materials also possess antibacterial properties and can play an important role in the repair of infectious bone defects. …”
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Pathological Roles of Neutrophil-Mediated Inflammation in Asthma and Its Potential for Therapy as a Target
Published 2017-01-01“…This review discusses neutrophils in asthma and potentially related targeted therapies.…”
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Roles of Lamiaceae plants from the arid and desert rangelands of Tunisia in human health and therapy
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From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies
Published 2025-02-01“…Regarding treatment, INMs play a key role in advanced strategies such as immunotherapy, magnetic hyperthermia, and synergistic combination therapy, which effectively overcome tumor-induced drug resistance and reduce systemic toxicity. …”
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The Effect of Acupuncture along with Conventional Therapies on the Treatment of Allergic Rhinitis: A Clinical Trial
Published 2025-01-01“…Therefore, the present study aimed at evaluating the effect of acupuncture along with conventional therapies on the treatment of AR. Materials and Methods: The present randomized, clinical trial was performed on 51 patients with AR. …”
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The Role of Connexin-43 in the Inflammatory Process: A New Potential Therapy to Influence Keratitis
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The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy
Published 2018-01-01“…., chronodisruption) and genetic/epigenetic factors may also play relevant roles in syndrome development. Overweight and/or obesity are very common in women with polycystic ovary syndrome, thus suggesting that some polycystic ovary syndrome and metabolic syndrome female phenotypes share common characteristics. …”
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Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy
Published 2024-12-01“…Gelatinases, specifically MMP-2 and MMP-9, play critical roles in the processes of tumor growth, invasion, and metastasis. …”
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Stem Cell-Derived Nanovesicles: A Novel Cell-Free Therapy for Wound Healing
Published 2021-01-01“…CDNs can shuttle various proteins, messenger RNAs, and microRNAs to regulate the activity of receptor cells, and they play important roles in skin wound healing. This article reviews recent research progress on CDNs for wound repair. …”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies
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Bringing MDMA-assisted therapy for PTSD to traditional healthcare systems: tending to set and setting
Published 2025-01-01“…Both are believed to play a critical role in the individual’s experience and efficacy of MDMA-AT. …”
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Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis
Published 2010-01-01“…Accumulating evidence indicates that ATP-binding cassette (ABC) transporter ABCG2 plays a key role in regulating the cellular accumulation of porphyrin derivatives in cancer cells and thereby affects the efficacy of photodynamic therapy and photodynamic diagnosis. …”
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ClpB chaperone as a promising target for antimicrobial therapy: A narrative review
Published 2025-01-01“…Notably, ClpB is present in all ESKAPE pathogens: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. ClpB plays a crucial role in reactivating and disaggregating proteins, enabling pathogens to survive under host-induced stress and conferring thermotolerance to bacterial cells. …”
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