Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging by Seul Ki Kim, Sang-Back Kim, Seul Bi Lee, Kang sub Kim, So-Ri Son, En Jin Choi, Byung Chul Park, Eunyoung Hong, You Ah Kim, Byoung Seok Moon, Sullim Lee

“…Abstract Reactive oxygen species (ROS) produced in the mitochondria of skin cells play a significant role in the degradation of the extracellular matrix and induction of inflammatory responses, both of which are major contributors to skin aging. …”
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Role of S100 Proteins in Colorectal Carcinogenesis by Paula Moravkova, Darina Kohoutova, Stanislav Rejchrt, Jiri Cyrany, Jan Bures

“…Possibly, in the future, S100 proteins will be a therapeutic target for tailored anticancer therapy.…”
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RIPK1 in necroptosis and recent progress in related pharmaceutics by Kunhou Yao, Zhihao Shi, Fengya Zhao, Cong Tan, Yixin Zhang, Hao Fan, Yingzhe Wang, Xingwang Li, Jun Kong, Qun Wang, Dingxi Li

“…In this paper, we outline the pathways of necroptosis and the role RIPK1 plays in them and suggest that targeting RIPK1 in therapy may help to inhibit multiple cell death pathways.…”
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Genetic Diversity, Repeat Motifs, and Natural Selection at the C-Terminal Knob-Associated Histidine Rich Protein (KAHRP) of Plasmodium falciparum Clinical Samples from Saudi Arabia by Saad M. Bin Dajem, Md Atique Ahmed, Marie Fe F Bohol, Syeda Wasfeea Wazid, Mohammed I. Shafeai, Fuad H. Rudiny, Ali M. Motaen, Kareem Morsy, Hani Alothaid, Ahmed A. Al-Qahtani

“…Plasmodium falciparum knob-associated histidine-rich proteins (PfKAHRPs) play an important role in cerebral malaria pathophysiology as well as pathogenesis of P. falciparum infections. …”
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Exosomes Derived from CXCR4-Overexpressing BMSC Promoted Activation of Microvascular Endothelial Cells in Cerebral Ischemia/Reperfusion Injury by Xutong Li, Ye Zhang, Yong Wang, Dan Zhao, Chengcheng Sun, Shaoting Zhou, Dongsheng Xu, Jing Zhao

“…In ischemia/reperfusion injury, ExoCXCR4 promoted the proliferation and tube formation of microvascular endothelial cells and play an antiapoptotic role via the Wnt-3a/β-catenin pathway.…”
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Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression by Agata Ossolińska, Patrycja Marta, Filip Huzarski, Gabriela Ferfecka, Klaudia Pawełek, Lucyna Stolarska, Magdalena Rosa-Bończak, Natalia Morawiecka, Olivier Carlton, Weronika Kłosowicz

“… Physical activity plays a critical role in promoting physical and mental health, positively influencing the prevention of non-communicable diseases (NCDs) and enhancing brain function. …”
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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Abstract Sphingolipid, ceramide for example, plays an essential role in regulating cancer cell death. …”
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A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer by David G. Watt, Campbell S. Roxburgh, Mark White, Juen Zhik Chan, Paul G. Horgan, Donald C. McMillan

“…The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. …”
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Prognostic significance of tumor angiogenesis markers in advanced cervical cancer undergoing chemotherapy by I Nyoman Bayu Mahendra, I Gde Sastra Winata, William Alexander Setiawan, Ida Bagus Agung Widnyana Putra, Putu Bagus Darmayasa

“…This underscores the need for reliable molecular markers to predict prognosis and optimize therapy. Angiogenesis plays a pivotal role in the development and progression of solid tumors, including cervical cancer. …”
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Reduced Serum Butyrylcholinesterase Activity Indicates Severe Systemic Inflammation in Critically Ill Patients by Aleksandar R. Zivkovic, Karsten Schmidt, Annette Sigl, Sebastian O. Decker, Thorsten Brenner, Stefan Hofer

“…Cholinergic neurotransmission plays an important role in the regulation of the immune response during inflammation. …”
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Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes by Maria Fransiska Priska Yulianti, Anita Lidesna Shinta Amat, Regina Marvina Hutasoit, Prisca Deviani Pakan

“… Background: Propionibacterium acnes is a bacterium found on the skin that plays a significant role in acne vulgaris. The inappropriate use of antibiotics can lead to resistance, necessitating the search for alternative therapies from plants with high antibacterial potential. …”
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Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy by Jingjing Liu, Chunyu Jiang, Xu Ma, Lishuai Feng, Jianbo Wang

“…Reendothelialization is an essential process in vascular injury following interventional therapy, and hyperglycemia in diabetes mellitus (DM) plays an important role in damaging endothelial layer integrity, leading to the retardance of reendothelialization and excessive neointimal formation. …”
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Cranial Cruciate Ligament Desmotomies in Sheep Resulting in Peroneus Tertius Injury by Peter J. Welsh, Crystal G. Collier, Holly M. Clement, Michael N. Vakula, Jeffrey B. Mason

“…The PT plays a crucial role in the normal gait of large animals, including sheep. …”
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A SYSTEMATIC ANALYSIS OF AI-EMPOWERED EDUCATIONAL TOOLS DEVELOPED IN INDIA FOR DISABLED PEOPLE by Shivani, Monika Gupta, Satinder Bal Gupta

“… Artificial Intelligence (AI) plays a multifaceted role in educating impaired people and has significantly enhanced the learning experience of disabled students. …”
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The role of chinese culture and strategic orientation in enhancing competitive advantage and firm performance in Indonesian chinese family companies by Susan Kustiwan, Asep Hermawan, Agustinus Sri Wahyudi

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A systematic review of pathophysiological and psychosocial measures in adaptive sports and their implications for coaching practice by Junyan Liu, Hongjun Yu, W. Catherine Cheung, Adam Bleakney, Yih-Kuen Jan

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A ketogenic diet regulates microglial activation to treat drug addiction by Jie Ji, Yi Tang

“…Here, we discuss recent research showing that a KD plays a variety of roles in controlling microglia-mediated inflammation, opening new treatment avenues to treat drug addiction. …”
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Interleukin-17: Potential Target for Chronic Wounds by Yasmin Hadian, Michelle D. Bagood, Sara E. Dahle, Apra Sood, R. Rivkah Isseroff

“…The significant burden of chronic wounds, which are often resistant to standard therapy, prompts further research on novel therapies. …”
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Structural modeling of NAD+ binding modes to PARP-1 by N. V. Ivanisenko, D. A. Zhechev, V. A. Ivanisenko

“…The nuclear protein poly (ADP-ribose) polymerase-1 (PARP-1) plays an important role in the signaling and repair of DNA. …”
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Intratumor heterogeneity: models of malignancy emergence and evolution by R. A. Ivanov, S. A. Lashin

“…Evolutionary dynamics plays a crucial role in the emergence and development of tumors, shaping the heterogeneity and adaptability of cancer cells. …”
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