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701
Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback
Published 2016-01-01“…The visual feedback is relevant to M1 cortex excitability modulation but the MVF plays a crucial role in promoting changes in intracortical inhibition in comparison to BVF. …”
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702
Understanding the role of sex on outcomes for the cancer patient undergoing treatment with immune checkpoint inhibitors: a scoping review protocol
Published 2022-07-01“…Introduction Immune checkpoint inhibitors (ICIs) have changed the treatment landscape for multiple cancer types. Sex plays an important role in both the development of cancer as well as the functioning of the immune system. …”
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703
ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics
Published 2021-01-01“…There is therefore an urgent need for additional therapies that complement vaccines and approved therapies such as antibodies in the fight to end or slow down the pandemic. …”
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704
Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis
Published 2022-01-01“…T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore, enhancing Mtb-specific T cell immune responses represents a promising therapeutic strategy against TB. …”
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705
Stachydrine targeting tumor-associated macrophages inhibit colorectal cancer liver metastasis by regulating the JAK2/STAT3 pathway
Published 2025-02-01“…The interaction between tumor-associated macrophages (TAMs) and tumor cells plays a pivotal role in the development of colorectal cancer liver metastases (CRLM) and represents a promising avenue for therapeutic intervention. …”
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706
The Effect of Music on the Happiness of Turkman Elderly in Day Care Centers
Published 2024-12-01“…The intervention consisted of 12 group music therapy sessions, each lasting 45-50 minutes, three times a week, involving the playing of happy Turkman music. …”
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707
Molecular docking of ferulic acid, bakuchiol and niazirin on peroxisome proliferator-activated receptor gamma (PPAR-γ) as anti-diabetic agents
Published 2024-08-01“…The PPAR-gamma protein plays a crucial role in lipid and carbohydrate metabolism, making it a key target for diabetes therapy. …”
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708
The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases
Published 2024-01-01“…This study aimed to quantify the role pharmacotherapy has played in clinical practice guidelines across a range of chronic diseases over the past 20 years. …”
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709
Apelin-13 Pretreatment Promotes the Cardioprotective Effect of Mesenchymal Stem Cells against Myocardial Infarction by Improving Their Survival
Published 2022-01-01“…Apelin plays an essential regulatory role in cell proliferation. …”
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710
Understanding phage BX-1 resistance in Vibrio alginolyticus AP-1 and the role of quorum-sensing regulation
Published 2025-02-01“…To fully realize the potential of phage therapy in aquaculture, a comprehensive understanding of phage-host interactions and their regulation is essential. …”
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711
The emerging roles of aberrant alternative splicing in glioma
Published 2025-02-01“…Consequently, AS constitutes a key regulatory mechanism that could serve as a target for future therapies. In this review, we explore how AS events, spliceosome components, and their regulatory mechanisms play a critical role in glioma development, highlighting their potential as targets for innovative therapeutic strategies against this challenging cancer.…”
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712
Dental Mesenchymal Stem/Stromal Cells and Their Exosomes
Published 2018-01-01“…The use of cellular exosomes as an important diagnostic marker and indicator of targeted cancer therapies is also discussed, while the importance of stem cells from human exfoliated deciduous teeth as a source of evolutionally young cells for future regenerative therapies is stressed. …”
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713
Maxillofacial Developmental and Occlusion Disorders in Children with Obstructive Sleep Apnea Syndrome
Published 2011-03-01“…Early diagnosis and appropriate therapy reverse maxillofacial developmental disorders in most of the cases.…”
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714
Recent Advances in DNA Systems for In Situ Telomerase Activity Detection and Imaging
Published 2025-01-01“…Telomeres play a key role in maintaining chromosome stability and cellular aging. …”
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715
Trends in research on novel antidepressant treatments
Published 2025-01-01“…Findings from studies using animal models of depression continue to play a crucial role in predicting and designing new therapeutic strategies. …”
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716
Antitumoral and Anti-inflammatory Roles of Somatostatin and Its Analogs in Hepatocellular Carcinoma
Published 2021-01-01“…A complete evaluation of the efficacy of somatostatin and SSAs is still the matter of intense debate, and, if deemed useful, these substances may play a beneficial role in the management of HCC patients.…”
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717
Identifying key genes in cancer networks using persistent homology
Published 2025-01-01“…Abstract Identifying driver genes is crucial for understanding oncogenesis and developing targeted cancer therapies. Driver discovery methods using protein or pathway networks rely on traditional network science measures, focusing on nodes, edges, or community metrics. …”
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718
Inducers of Autophagy and Cell Death: Focus on Copper Metabolism
Published 2025-01-01“…Copper is an essential trace element in biological systems, playing a key role in various physiological functions, including redox reactions and energy metabolism. …”
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719
Gastroesophageal reflux disease and functional dyspepsia: clinical efficacy and safety of prokinetic choice
Published 2014-11-01“…Motility disorder of gastroesophageal zone plays a leading part in pathogenesis of these diseases that assumes application prokinetics as a baseline therapy. …”
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720
CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report
Published 2018-01-01“…However, whether Treg dysregulation in CLL and ALL plays a key role or it rather represents a simple epiphenomenon is still a matter of debate. …”
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