MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease by Xiaojuan Shao, Jintao Li, Fumin Xu, Dongfeng Chen, Kaijun Liu

“…MiR-155 may be a potential marker for IBD-targeted therapy.…”
Get full text

Ecological and Specific Evidence-Based Safe Return To Play After Anterior Cruciate Ligament Reconstruction In Soccer Players: A New International Paradigm by Florian Forelli, Nicolas Le Coroller, Maxime Gaspar, Geoffrey Memain, Georgios Kakavas, Nicholas Miraglia, Patrice Marine, Pascal Maille, Timothy E Hewett, Alexandre JM Rambaud

Get full text

A Nation-Wide Survey of High School Baseball Coaches’ Perceptions Indicates their Arm Care Programs Play a Role in Injury Prevention by K A Matsel, E E Weiss, R J Butler, M C Hoch, P M Westgate, T R Malone, T L Uhl

Get full text

Antibiotic Therapy for Crohn’s Disease: A Review by Simon Lal, A Hillary Steinhart

Get full text

Impact of Incretin-Based Therapies on Adipokines and Adiponectin by Habib Yaribeygi, Mina Maleki, Stephen L. Atkin, Tannaz Jamialahmadi, Amirhossein Sahebkar

“…Adipokines are closely involved in most metabolic pathways and play an important modulatory role in lipid and carbohydrate homeostasis as they are involved in the pathophysiology of most metabolic disorders. …”
Get full text

Glioma Stem Cells: Signaling, Microenvironment, and Therapy by Brandon D. Liebelt, Takashi Shingu, Xin Zhou, Jiangong Ren, Seul A. Shin, Jian Hu

“…The glioma stem cell (GSC) subpopulation has been identified in glioblastoma and likely plays a key role in resistance of these tumors to conventional therapies as well as recurrent disease. …”
Get full text

Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia by Jing Wang, Terry W. Wright, Francis Gigliotti

“…Immune-mediated inflammatory responses play an important role in the pathogenesis of Pcp, and may be even more significant in determining the outcome of Pcp than direct damage due to the organism itself. …”
Get full text

Hopping backward to move forward: Single-leg backward hopping can better detect decreased quadriceps strength induced by a fatigue protocol compared to forward and vertical hopping by Yu Song, Lauren Salsgiver, Kaden Van Valkenburg, Natalie Christofferson, Yessica Lo, Zhichen Feng, Brenna McGuinness, Boyi Dai

Get full text

The Role of PPARs in the Endothelium: Implications for Cancer Therapy by David Bishop-Bailey, Karen E. Swales

Get full text

Mediators of Inflammation in Topical Therapy of Skin Cancers by Vlad Mihai Voiculescu, Cristina Victoria Lisievici, Mihai Lupu, Cristina Vajaitu, Carmen Cristina Draghici, Alexandra Victoria Popa, Iulia Solomon, Teona Ioana Sebe, Maria Magdalena Constantin, Constantin Caruntu

“…Taking into consideration that the immune system plays a very important role in the development of melanoma and non-melanoma skin cancers, which have a high prevalence in immunosuppressed patients and after prolonged ultraviolet radiation, the interest in developing novel therapies, in particular targeting the inflammation in cancer, has increased in the past years. …”
Get full text

The Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST) Performance in Elite Team Handball Players Playing with Shoulder Pain, Previous Pain, or No Pain by Tina Piil Torabi, Jesper Bencke, Roland van den Tillaar

Get full text

CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses by Alice Bergamini, Barbara Camisa, Attilio Bondanza, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Camilla Bove, Silvia Arcangeli, Laura Falcone, Rita El Khoury, Anna De Lucia

Get full text

Prospects of Antiangiogenic Therapy for Portal Hypertension in Liver Cirrhosis by D. V. Garbuzenko

“…Angiogenesis is shown to play an important role in the pathogenesis of liver cirrhosis. …”
Get full text

Role of Interferons in the Development of Diagnostics, Vaccines, and Therapy for Tuberculosis by Kai Ling Chin, Fadhilah Zulkipli Anis, Maria E. Sarmiento, Mohd Nor Norazmi, Armando Acosta

Get full text

Targeting Inflammation in Emerging Therapies for Genetic Retinal Disease by Ishaq A. Viringipurampeer, Abu E. Bashar, Cheryl Y. Gregory-Evans, Orson L. Moritz, Kevin Gregory-Evans

Get full text

Tumor microbiome: roles in tumor initiation, progression, and therapy by Shengxin Zhang, Jing Huang, Zedong Jiang, Huan Tong, Xuelei Ma, Yang Liu

Get full text

Promising LOX proteins for cartilage-targeting osteoarthritis therapy by Luca Morici, Eric Allémann, Olivier Jordan, Ines Nikolić

“…Potential LOX inhibitoion strategies for drug development in advanced OA therapy, particularly for local intraarticular delivery, were listed and discussed for each target type. …”
Get full text

Liver Injury Induced by Anticancer Chemotherapy and Radiation Therapy by Y. Maor, S. Malnick

Get full text

Mesenchymal Stem Cells as a Prospective Therapy for the Diabetic Foot by Qinan Wu, Bing Chen, Ziwen Liang

“…Mesenchymal stem cells are an abundant source of stem cells which occupy a special position in cell therapies, and recent studies have suggested that mesenchymal stem cells can play essential roles in treatments for the diabetic foot. …”
Get full text

Role of Interleukin- (IL-) 17 in the Pathogenesis and Targeted Therapies in Spondyloarthropathies by I-Tsu Chyuan, Ji-Yih Chen

“…In addition to several well-known proinflammatory cytokines, recent studies suggest that IL-17 plays a pivotal role in the pathogenesis of SpA. …”
Get full text