Computational modeling approaches to studying the dynamics of oncolytic viruses by Dominik Wodarz

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"He Has Rescued Me from Danger" by Sarah Bishop

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Responsive nanomaterials in biomedicine, patent path and prospect analysis by Xinrui Liu, Hongmei Yuan

“…Keyword co-occurrence analysis highlights key research hotspots, including biomimetic design, multimodal synergistic therapies, and emerging response mechanisms. In the future, responsive nanomaterials are expected to play a pivotal role in personalized medicine, multifunctional carrier design, and complex disease management, providing novel insights and technological support for precision medicine.…”
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Transferrin Receptor 2 in Canine Testicular Tumors: An Emerging Key Role in Seminomas by Rebecca Leandri, Sara Buonocore, Karen Power

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MicroRNAs in atrial fibrillation – have we discovered the Holy Grail or opened a Pandora’s box? by Alkora Ioana Balan, Alina Scridon

“…Through post-transcriptional regulation of genes, miRNAs have been shown to play crucial roles in AF-related structural and electrical atrial remodeling. …”
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RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melan... by Sara Egea‐Rodriguez, Renáta Váraljai, Thierry M. Nordmann, Restuan Lubis, Manuel Philip, Florian Rambow, Alexander Roesch, Michael Flaig, Susanne Horn, Raphael Stoll, Fang Zhao, Annette Paschen, Bert Klebl, Ian D. Hickson, Dirk Schadendorf, Matthias Mann, Iris Helfrich

“…RECQL4, a RecQ‐like helicase, plays a central role in DNA replication and repair as part of the DNA damage response, a pathway implicated in enhancing efficacy of immune checkpoint inhibitor (ICI) therapies. …”
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A Pilot Study on the Freelisting Method Among Adolescents with Chronic Musculoskeletal Pain: Feasibility, Acceptability and Study Findings by Sabrina Gmuca, Dori Abel, Mackenzie McGill, Daneka Stryker, Eda Akpek, Whitney Eriksen, Pamela F. Weiss, Peter F. Cronholm

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Portrait of WWP1: the current state in human cancer by Jiaming Lei, Jun Chen, Wenwen Yu, Qing Wu, Shuang Jing, Yuanguang Tang, Li Lin, Meichun Hu

“…WWP1, a member of the C2-WW-HECT E3 ligase family, is an E3 ubiquitin-protein ligase containing WW domains. This enzyme plays a critical role in regulating diverse cellular processes. …”
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Deciphering Oxidative Stress in Cardiovascular Disease Progression: A Blueprint for Mechanistic Understanding and Therapeutic Innovation by Zhaoshan Zhang, Jiawei Guo

“…Oxidative stress plays a pivotal role in the pathogenesis and progression of cardiovascular diseases (CVDs). …”
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Spinoza’s Strong Eudaimonism by Brandon Smith

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Molecular Mechanisms of Alzheimer’s Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for... by Eun Hee Ahn, Jae-Bong Park

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Tissue‐resident memory T cells in diseases and therapeutic strategies by Daoyuan Xie, Guanting Lu, Gang Mai, Qiuyan Guo, Guofeng Xu

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Extracellular Vesicles in Periodontitis: Pathogenic Mechanisms and Therapeutic Potential by Zhang L, Li X, Zhang B, Li R

“…Keywords: extracellular vesicles, outer membrane vesicles, dental stem cells, periodontitis, pathogenesis, therapy…”
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MicroRNA-150-3p enhances the antitumour effects of CGP57380 and is associated with a favourable prognosis in non-small cell lung cancer by Hongmei Zheng, Songqing Fan, Jiadi Luo, Qiuyuan Wen, Hongjing Zang

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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

“…Abstract Background Immunotherapy and radiotherapy play crucial roles in the transformation therapy of locally advanced pancreatic cancer; however, the exploration of effective predictive biomarkers has been unsatisfactory. …”
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The clinical application of artificial intelligence in cancer precision treatment by Jinyu Wang, Ziyi Zeng, Zehua Li, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao

“…In tumor precision treatment, artificial intelligence plays a crucial role in individualizing both conventional and emerging therapies. …”
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A Korean Patient With Leber Congenital Amaurosis and a Homozygous RPE65 Variant Originating From a Paternal Uniparental Isodisomy by Hane Lee, Dongseok Moon, Rin Khang, Go Hun Seo, Chang Ki Yoon, Un Chul Park, Kyu Hyung Park, Eun Kyoung Lee

“…RPE65, one of the causative genes for LCA, encodes retinoid isomerohydrolase, an enzyme that plays a critical role in regenerating visual pigment in photoreceptor cells. …”
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Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus by Dongdong Lin, Cong Tang, Junbin Wang, Yun Yang, Hao Yang, Yanan Zhou, Wenhai Yu, Bai Li, Qing Huang, Haixuan Wang, Ran An, Xiaoming Liang, Yuhuan Yan, Longhai Yuan, Xuena Du, Yuxia Yuan, Yanwen Li, Shuaiyao Lu

“…This research underscores the need for appropriate animal models in CHIKV studies and informs the development of targeted therapies to address its systemic effects.…”
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Trimodal organ‑preserving treatment of muscle‑invasive bladder cancer by A. V. Troianov, I. O. Dementev, I. N. Zaborsky, V. S. Chaykov, O. B. Karyakin, Yu. V. Gumenetskaya

“…Careful selection of patients plays a key role. The modern approach to trimodal therapy (TMT) is as follows: complete transurethral resection of the bladder (TURB), neoadjuvant or adjuvant chemotherapy, subsequent assessment of the response to treatment (re‑staging with TURB) should be performed; with a complete pathomorphological response, a course of remote radiation therapy up to TFD 60–66 Gy in the case of traditional fractionation (focal radiation therapy and the use of hypofractionation modes are also possible), using modern irradiation technologies (IGRT, IMRT). …”
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Study approaches mediate associations between learning environment and academic performance by Tore Bonsaksen, Amayra Tannoubi, Linda Stigen, Astrid Gramstad, Tove Carstensen, Gry Mørk

“…Background While study approaches have been directly associated with students’ academic performance, learning environment factors may play a more indirect role. The aim of this study was (i) to assess learning environment factors as predictors of students’ average exam grades, and (ii) whether study approaches mediated associations between learning environment factors and exam grades.Methods Three annual surveys (2017–2019) yielded data from a total of 263 Norwegian occupational therapy students. …”
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