High-grade liver injury: outcomes with a trauma surgery–liver surgery collaborative approach by J Wallis Marsh, Abhinav Humar, Jason L Sperry, David A Geller, Deepika Mohan, Timothy R Billiar, Juan Carlos Puyana, Brian Zuckerbraun, Joshua B Brown, Matthew D Neal, Matthew R Rosengart, David Newhouse, Christine Leeper, Andrew B Peitzman, Raquel Forsythe, Rafael G Ramos-Jimenez, Andrew-Paul Deeb, Evelyn I Truong, Sowmya Narayanan, Louis Alarcon, Graciela M Bauza, Vaishali Dixit Schuchert, Gregory Watson, Amit D Tevar

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Supra-Annular Versus Intra-Annular Self-Expanding Valves in Small Aortic Annulus: A Propensity Score-Matched Study by Michel Pompeu Sá, MD, MSc, MHBA, PhD, Danial Ahmad, MD, MPH, Yisi Wang, MPH, Floyd Thoma, BS, Amber Makani, MD, Dustin Kliner, MD, Catalin Toma, MD, David West, MD, Derek Serna-Gallegos, MD, Ibrahim Sultan, MD

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Inter-rater reliability and prognostic value of baseline Radiographic Assessment of Lung Edema (RALE) scores in observational cohort studies of inpatients with COVID-19 by Andrew I Kim, William Bain, Alison Morris, Barbara Methe, Bryan J McVerry, Georgios D Kitsios, Daniel Kotok, Janet S Lee, Nameer Al-Yousif, Christine E Girard, Jana J Jacobs, Konstantin Golubykh, Hafiz Qurashi, Michael Lu, Saketram Komanduri, Anatoliy Korzhuk, Halimat O Lawal, Nicholas Abourizk, Caitlin Schaefer, Kevin J Mitchell, Catherine M Dietz, Ellen K Hughes, Clara S Brandt, Georgia M Fitzgerald, Robin Joyce, Asmaa S Chaudhry, Jose D Rivera, Shruti Shettigar, Allen Lavina, Samantha R Gillenwater, Anas Hadeh, Faraaz A Shah, Matthew Bittner, Niall Prendergast, John Evankovich, Navitha Ramesh, Cathy Kessinger

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Strategies to Promote ResiliencY (SPRY): a randomised embedded multifactorial adaptative platform (REMAP) clinical trial protocol to study interventions to improve recovery after s... by Derek C Angus, Jennifer Holder-Murray, Katherine Moll Reitz, Christopher W Seymour, Jennifer Vates, Melanie Quintana, Kert Viele, Michelle Detry, Michael Morowitz, Alison Morris, Barbara Methe, Jason Kennedy, Brian Zuckerbraun, Timothy D Girard, Oscar C Marroquin, Stephen Esper, Anne B Newman, Scott Berry, Matthew Neal

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Differential impact of TIM-3 ligands on NK cell function by Xin Zhang, Lazar Vujanovic, Riyue Bao, Robert L Ferris, Tullia C Bruno, Aditi Kulkarni, Hridesh Banerjee, Housaiyin Li, Juncheng Wang, Lawrence P Kane, Pragati Upadhyay, Jennifer L Anderson, Onyedikachi Victor Onyekachi, Lidia M R B Arantes

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Advances in Pediatric Urologic Laparoscopy by M. C. Smaldone, E. Polsky, D. J. Ricchiuti, S. G. Docimo

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Revision Anterior Cruciate Ligament Reconstruction in Combination With Meniscal and Osteochondral Allograft Transplantation for Complex Knee Injury by Denisse Loya, M.D., M.Sc., Janina Kaarre, M.D., M.Sc., Stephen E. Marcaccio, M.D., Ehab M. Nazzal, M.D., Christopher J. Como, M.D., Zachary J. Herman, M.D., Liane M. Miller, M.D., Volker Musahl, M.D.

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Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings (HumAn-1): protocol for a randomised controlled trial by Éimhín Ansbro, Jing Luo, Chung-Chou H Chang, Kaushik Ramaiya, Bruce L Rollman, Sylvia Kehlenbrink, Sae-Rom Chae, Abigail Foulds, Claire Josey, Christina Lalama, Margaret L Prust, Bedowra Zabeen, Graham Ogle

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A finite element model for biomechanical characterization of ex vivo peripheral nerve dysfunction during stretch by Nicholas C. Vasas, Adam M. Forrest, Nathaniel A. Myers, Michael B. Christensen, Jenny L. Pierce, Sidney M. Kaufmann, Kimberly B. Lanaghen, Randal C. Paniello, Julie M. Barkmeier‐Kraemer, Jonathan P. Vande Geest

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Evolution in Response to Management Increases Invasiveness Among Experimental Populations of Duckweed (Lemna minor) by Taylor A. Zallek, Martin M. Turcotte

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Observations from a Multicentre Study on the Use of the Sputum Specimen in Patients Hospitalized with Community-Acquired Pneumonia by EL Taylor, TJ Marrie, MJ Fine, DS Obroskyl, WN Kapoor, C Coley, DE Singer

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Noteworthy: News Briefs from PA Libraries by Jacob Gordon

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Table of Contents by Kate Cummings

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In the PaLRaP Spotlight: Gillian Hayward, Library Manager by Stephanie Campbell

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Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review by Francesco M Marincola, Alessandra Cesano, Yana G Najjar, Davide Bedognetti, Marco Ruella, Sarah Warren, Christine Spencer, Elad Ziv, Tomas Kirchhoff, Jennifer McQuade, Tullia C Bruno, Jakob Nikolas Kather, Allison Betof Warner, Christian Hammer, Alberto Carturan, Ryan Augustin, Rhine Shen, Winson S Ho, Rongze O Lu, Luigi Barrea, Violena Pietrobon, Laura Soldati

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Functional and Practical Insights Into the Genetic Basis of Takayasu Arteritis by Desiré Casares‐Marfil, Amr H. Sawalha

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Tendon Stem/Progenitor Cells and Their Interactions with Extracellular Matrix and Mechanical Loading by Chuanxin Zhang, Jun Zhu, Yiqin Zhou, Bhavani P. Thampatty, James H-C. Wang

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Sibling Species in the Eurydice Group of Lethe (Lepidoptera: Satyridae) by Rino T. Cardé, Arthur M. Shapiro, Harry K. Clench

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Diagnosis, Therapy, and Prognosis for Hepatocellular Carcinoma by Zhigang Ren, Xiaochao Ma, Zhenfeng Duan, Xinhua Chen

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RNA-seq reproducibility of Pseudomonas aeruginosa in laboratory models of cystic fibrosis by Rebecca P. Duncan, Gina R. Lewin, Daniel M. Cornforth, Frances L. Diggle, Ananya Kapur, Dina A. Moustafa, Yasmin Hilliam, Jennifer M. Bomberger, Marvin Whiteley, Joanna B. Goldberg

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