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The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target
Published 2025-12-01“…Sulfur metabolism is an essential aspect of fungal physiology and pathogenicity. Fungal sulfur metabolism comprises anabolic and catabolic routes that are not well conserved in mammals, therefore is considered a promising source of prospective novel antifungal targets. …”
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A multiplex method for rapidly identifying viral protease inhibitors
Published 2025-01-01Get full text
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Mechanism of Exogenous Silicon in Enhancing Cold Stress Tolerance in <i>Solanum lycopersicum</i> L. Seedlings: Insights from Resistance and Quality Indicators
Published 2024-12-01“…Silicon (Si), recognized as a beneficial element, is posited to mitigate the adverse effects of such stress on plant physiology. This study explores whether exogenous Si fertilizer can effectively alleviate the stress of low temperature and cold damage on tomato plant growth, fruit yield, and quality. …”
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Whole genome sequencing in early onset advanced heart failure
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A karyomorphological study on Actaea acuminata, A. asiatica, and A. erythrocarpa (Ranunculaceae)
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Related Pentacyclic Triterpenes Have Immunomodulatory Activity in Chronic Experimental Visceral Leishmaniasis
Published 2021-01-01“…Thus, the aim of the present study was to compare the in vitro antileishmanial activity of the triterpenes betulin (Be), lupeol (Lu), and ursolic acid (UA); analyze the physiology and morphology of affected organelles; analyze the toxicity of selected triterpenes in golden hamsters; and study the therapeutic activity of triterpenes in hamsters infected with L. …”
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Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers—A Prospective...
Published 2021-01-01“…Our study aimed to compare changes in BUN versus the Bedside Index for Severity in Acute Pancreatitis (BISAP) score and the Acute Physiology and Chronic Health Evaluation-II score (APACHE-II), as well as other laboratory tests such as haematocrit and its variations over 24 h and C-reactive protein, in order to determine the most accurate test for predicting mortality and severity outcomes in AP. …”
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Assessing the potential of germplasm collections for the management of genetic diversity: the case of the French National Cryobank
Published 2024-02-01“…Overall, breeds with a large commercial distribution had more donors in the collection than local breeds, while the number of doses available was mainly determined by the physiology of the species. An adapted version of the Gini-Simpson equitability index revealed an unbalanced number of donors between breeds for some species. …”
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Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study
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