Acute and Repeated Dose 28-Day Oral Toxicity Study of the Aqueous Extracts from the Leafy Stem and Fruit of Pedalium murex D.Royen EX.L in Wistar Rats by Gérard Bessan Dossou-Agoin, Maxime Machioud Sangaré-Oumar, Téniola Isabelle Sacramento, Mariette Sindété, Egnon Jacques Hougbénou-Houngla, Nounagnon Darius Tossavi, Simon Azonbakin, Adam Gbankoto

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In Vitro Aberrometric Assessment of a Multifocal Intraocular Lens and Two Extended Depth of Focus IOLs by Vicente J. Camps, Angel Tolosa, David P. Piñero, Dolores de Fez, María T. Caballero, Juan J. Miret

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Effects of anti-inflammatory drugs on fever and neutrophilia induced by Clostridium difficile toxin B by R. A. Cardoso, A. A. Melo Filho, M. C. C. Melo, D. M. Lyerly, T. D. Wilkins, A. A. M. Lima, R. A. Ribeiro, G. E. P. Souza

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Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats by Madhavan Nampoothiri, Jessy John, Nitesh Kumar, Jayesh Mudgal, Gopalan Kutty Nampurath, Mallikarjuna Rao Chamallamudi

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A Snake Venom-Secreted Phospholipase A2 Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis by Elbio Leiguez, Karina Cristina Giannotti, Mariana do Nascimento Viana, Márcio Hideki Matsubara, Cristina Maria Fernandes, José Maria Gutiérrez, Bruno Lomonte, Catarina Teixeira

“…We found that MT-III activated PPAR-γ and PPAR-β/δ and increased the protein levels of both transcription factors and CD36 in macrophages. Pharmacological interventions evidenced that PPAR-γ, PPAR-β/δ, and CD36 as well as the endoplasmic reticulum enzymes ACAT and DGAT are essential for LD formation. …”
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Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder by Dalia Moore, Brittney M. Meays, Lepakshe S. V. Madduri, Farah Shahjin, Subhash Chand, Meng Niu, Abrar Albahrani, Chittibabu Guda, Gurudutt Pendyala, Howard S. Fox, Sowmya V. Yelamanchili

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Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat by Mladena Lalić-Popović, Velibor Vasović, Boris Milijašević, Svetlana Goločorbin-Kon, Hani Al-Salami, Momir Mikov

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Anti-Inflammatory Effects of Adrenomedullin on Acute Lung Injury Induced by Carrageenan in Mice by Talero Elena, Di Paola Rosanna, Mazzon Emanuela, Emanuela Esposito, Motilva Virginia, Cuzzocrea Salvatore

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Role of Lactate in Inflammatory Processes: Friend or Foe by Carolina Manosalva, John Quiroga, John Quiroga, Alejandra I. Hidalgo, Pablo Alarcón, Nicolás Ansoleaga, Nicolás Ansoleaga, María Angélica Hidalgo, Rafael Agustín Burgos

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Rapid, Sensitive and Validated Ultra-Performance Liquid Chromatography/Mass Spectrometric Method for the Determination of Fenofibric Acid and its Application to Human Pharmacokinet... by Sunil K. Dubey, Manoj S. Tomar, Anil Kumar Patni, Arshad Khuroo, Simrit Reyar, Tausif Monif

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Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion by Ge Kuang, Qin He, Yunmei Zhang, Ruichun Zhuang, Anling Xiang, Qingsong Jiang, Ying Luo, Junqing Yang

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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication by Jide Tian, Hoa Dang, Angela Hu, Willem Xu, Daniel L. Kaufman

“…However, GABA and the most clinically applicable GABA-R ligands may be suboptimal for the long-term treatment of diabetes due to their pharmacological properties or potential side-effects on the central nervous system (CNS). …”
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The emerging role of 12/15-lipoxygenase in ischemic stroke by Xuening Wang, Qiuji Shao, Yuan Gao

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Ethnomedical Knowledge of Plants Used in Nonconventional Medicine for Wound Healing in Lubumbashi, Haut-Katanga Province, DR Congo by Bashige Chiribagula Valentin, Okusa Ndjolo Philippe, Manya Mboni Henry, Bakari Amuri Salvius, Masengu Kabeya Suzanne, Félicien Mushagalusa Kasali, Lumbu Simbi Jean Baptiste

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Characterization of a pleomorphic rhabdomyosarcoma cell line by Sandra Stickler, Clemens Lang, Maximilian Rieche, Marie-Therese Eggerstorfer, Martin Hohenegger, Maximilian Hochmair, Gerhard Hamilton

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Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1 by Fan Bu, Gang Ye, Hailey Turner-Hubbard, Morgan Herbst, Bin Liu, Fang Li

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One-Year Results of an Algorithmic Approach to Managing Failed Back Surgery Syndrome by Martín Avellanal, Gonzalo Diaz-Reganon, Alejandro Orts, Silvia Soto

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Therapeutic drug monitoring of atypical antipsychotic drugs by Grundmann Milan, Kacirova Ivana, Urinovska Romana

“…Therapeutic drug monitoring (TDM) of antipsychotic drugs is the specific method of clinical pharmacology, which involves measurement of drug serum concentrations followed by interpretation and good cooperation with the clinician. …”
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Cytokines as Therapeutic Targets for the Gastrointestinal Manifestations of Scleroderma by Jennifer M Raoul, Monica Verma, Ernest Tan, Theresa C Peterson

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Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment by Tatsuya Usui, Masashi Sakurai, Shuhei Enjoji, Hideyoshi Kawasaki, Koji Umata, Takashi Ohama, Nobuyuki Fujiwara, Ryotaro Yabe, Shunya Tsuji, Hideyuki Yamawaki, Shoichi Hazama, Hiroko Takenouchi, Masao Nakajima, Ryouichi Tsunedomi, Nobuaki Suzuki, Hiroaki Nagano, Koichi Sato

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