The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model by Jan Dusek, Ivana Mejdrová, Klára Dohnalová, Tomas Smutny, Karel Chalupsky, Maria Krutakova, Josef Skoda, Azam Rashidian, Ivona Pavkova, Kryštof Škach, Jana Hricová, Michaela Chocholouskova, Lucie Smutna, Rajamanikkam Kamaraj, Miloš Hroch, Martin Leníček, Stanislav Mičuda, Dirk Pijnenburg, Rinie van Beuningen, Michal Holčapek, Libor Vítek, Magnus Ingelman-Sundberg, Oliver Burk, Thales Kronenberger, Radim Nencka, Petr Pavek

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Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression by Juan Du, Ruyun Liu, Lin Ma, Yue Liu, Wei Wei, Ning Liu, Qiuhua Cao, Jianqiang Yu

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Static Magnetic Field Accelerates Diabetic Wound Healing by Facilitating Resolution of Inflammation by Wenlong Shang, Guilin Chen, Yinxiu Li, Yujuan Zhuo, Yuhong Wang, Zhicai Fang, Ying Yu, Huiwen Ren

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Cigarette Smoke Suppresses the Surface Expression of c-kit and FcεRI on Mast Cells by M. E. Givi, B. R. Blokhuis, C. A. Da Silva, I. Adcock, J. Garssen, G. Folkerts, F. A. Redegeld, E. Mortaz

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The effect of different strains of Helicobacter pylori on platelet aggregation by Paul A Corcoran, John C Atherton, Steve W Kerrigan, Torkel Wadstrom, Frank E Murray, Richard M Peek, Desmond J Fitzgerald, Dermot M Cox, Michael F Byrne

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GDF11 restores the impaired function of EPCs-MA by promoting autophagy: GDF11 ameliorates endothelial progenitor cell aging by promoting autophagy by Liu Donghua, Zhang Yang, Liu Xin, Huang Qihe, Zhang Xiaofang, Yang Rui, Zhao Yue, Li Penghui, He Jiayi, Zhang Kexiao, Pan Zhenwei, Liu Huiwen, Yang Baofeng

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Protective Effects and Mechanisms of Dendrobium nobile Lindl. Alkaloids on PC12 Cell Damage Induced by Aβ25-35 by Yuan Liu, Tingting Pi, Xiaohui Yang, Jingshan Shi

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A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor by Xian-Hui Zhu, Ya-Ping Zhou, Qiao Zhang, Ming-Yi Zhu, Xiao-Wei Song, Jun Li, Jiang Chen, Yun Shi, Kang-Jian Sun, Yong-Jie Zhang, Jing Zhang, Tian Xia, Bao-Sheng Huang, Fan Meng, Qi-Gang Zhou

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Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4 by Ming Zhang, Chun-Mei Wang, Jing Li, Zhao-Jie Meng, Sheng-Nan Wei, Ji Li, Richard Bucala, Yu-Lin Li, Li Chen

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Simultaneous Quantification of 25-Hydroxyvitamin D3 and 24,25-Dihydroxyvitamin D3 in Rats Shows Strong Correlations between Serum and Brain Tissue Levels by Ying Xue, Xin He, Huan-De Li, Yang Deng, Miao Yan, Hua-Lin Cai, Mi-Mi Tang, Rui-Li Dang, Pei Jiang

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Milk Products Containing Bioactive Tripeptides Have an Antihypertensive Effect in Double Transgenic Rats (dTGR) Harbouring Human Renin and Human Angiotensinogen Genes by Tiina Jauhiainen, Taru Pilvi, Zhong Jian Cheng, Hannu Kautiainen, Dominik N. Müller, Heikki Vapaatalo, Riitta Korpela, Eero Mervaala

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Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles by Paola A. Castagnino, Derick A. Haas, Luca Musante, Nathalia A. Tancler, Bach V. Tran, Rhonda Kean, Alexandra R. Steck, Luis A. Martinez, Elahe A. Mostaghel, D. Craig Hooper, Felix J. Kim

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Analysis of the cardiotoxic and myorelaxant effects of camphor on fish of the Nile tilapia species (Oreochromis niloticus) (Linnaeus 1758) by Clarissa Araújo da Paz, Suzane Maia de Oliveira, Maria Klara Otake Hamoy, Murilo Farias dos Santos, Anthony Lucas Gurgel do Amaral, Anara de Sousa Barbosa, Luciana Eiró-Quirino, Daércio José de Macedo Ribeiro Paixão, Luis André Luz Barbas, Dielly Catrina Favacho Lopes, Marcelo Ferreira Torres, Moisés Hamoy

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β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis by Yijia Zhang, Xinya Zhu, Liyuan Chen, Tianyu Gao, Guang Chen, Jin Zhu, Guoyu Wang, Daiying Zuo

“…Additionally, mechanistic studies employed pharmacological inhibitors and genetic approaches targeting β-catenin, OSM, and STAT3 signaling.Notably, elevated expression of OSM and LOXL2 in PDAC specimens significantly correlated with poor patient survival. …”
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Transmembrane Prostate Androgen-Induced Protein 1 Molecular Modeling and Refinement Using Coarse-Grained Molecular Dynamics by Imam Adi Wicaksono, Wanda Destiarani, Shidqi Fajri Romadhon, Bagas Adi Prasetya Nugraha, Muhammad Yusuf, Tiana Milanda, Riezki Amalia

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Risk factors for severe adverse drug reactions in hospitalized patients by Petrović Nemanja Z., Pejčić Ana V., Milosavljević Miloš N., Janković Slobodan M.

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Effect of Cordyceps militaris extract containing cordycepin on the adipogenesis and lipolysis of adipocytes by Kazuya Kusama, Kodai Oka, Yumi Yashiro, Kanoko Yoshida, Hiroaki Miyaoka, Kazuhiro Tamura

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Effects of esculentoside A on turnour necrosis factor production by mice peritoneal macrophages by Fang Jun, Zheng Qin Yue, Wang Hong Bin, Ju Dian Wen, Yi Yang Hua

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Atherogenic ω-6 Lipids Modulate PPAR- EGR-1 Crosstalk in Vascular Cells by Jia Fei, Carla Cook, Miriah Gillespie, Bangning Yu, Khyra Fullen, Nalini Santanam

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Effects of Borneol on Pharmacokinetics and Tissue Distribution of Notoginsenoside R1 and Ginsenosides Rg1 and Re in Panax notoginseng in Rabbits by Shixiang Wang, Weijin Zang, Xinfeng Zhao, Weiyi Feng, Ming Zhao, Xi He, Qinshe Liu, Xiaohui Zheng

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