Attitudes of Final-Year Medical Students in Jordan Towards Volunteering During a Pandemic by Alassaf A, Gharaibeh L, Alkubaisi F, Alkhawaldeh M, Dababseh S, Odeh R

“…Abeer Alassaf,1 Lobna Gharaibeh,2 Fatima Alkubaisi,3 Majd Alkhawaldeh,3 Sohayla Dababseh,3 Rasha Odeh1 1Department of Pediatrics, The University of Jordan, Amman, Jordan; 2Pharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan; 3School of Medicine, The University of Jordan, Amman, JordanCorrespondence: Abeer Alassaf, Department of Pediatrics, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan, Tel +962 6 5353444 extn 2767, Fax +962 6 5356746, Email dr_abeerassaf@hotmail.comBackground: During COVID-19 pandemic in Jordan, a number of medical students participated in voluntary work. …”
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Native and alien plant species inventory and diversity in disturbed forests and its economic value by J.J.C. Garces

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Exosomal miRNAs involvement in pathogenesis, diagnosis, and treatment of rheumatoid arthritis by Mahvash Sadeghi, Jalil Tavakol Afshari, Afsane Fadaee, Mohammadreza Dashti, Fatemeh Kheradmand, Sajad Dehnavi, Mojgan Mohammadi

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A meta-analysis on the impact of concurrent or pre-existing cancer diagnosis on acute myocardial infarction outcomes. by Jie Wang, Jia Yu

“…Early interventions, such as close monitoring of cardiac function, lifestyle modifications, and targeted pharmacological therapies, might help mitigate the risk of AMI and improve overall clinical outcomes. …”
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Exploring Lipoprotein-Associated Phospholipase A2 Levels in Iraqi Patients with Stable Angina: Insights from Coronary Angiography Diagnosis by Aseel Ghassan Daoud, Wassan Abdul Kareem Abbas, Ahmed Yousif Hasan, Maha N. Abu Hajleh

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Evidence of Presynaptic Localization and Function of the c-Jun N-Terminal Kinase by Silvia Biggi, Lucia Buccarello, Alessandra Sclip, Pellegrino Lippiello, Noemi Tonna, Cristiano Rumio, Daniele Di Marino, Maria Concetta Miniaci, Tiziana Borsello

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Diabetic Cataract in Spontaneously Diabetic Torii Fatty Rats by Kasumi Kikuchi, Miyuki Murata, Kousuke Noda, Satoru Kase, Yoshiaki Tagawa, Yasushi Kageyama, Masami Shinohara, Tomohiko Sasase, Susumu Ishida

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Angiotensin Inhibition Reduces the Risk of Subarachnoid Hemorrhage in Patients With Hypertension by Mohammad Hossein Abbasi, Colleen M. Brensinger, Emily K. Acton, Christopher G. Favilla, Jan‐Karl Burkhardt, Scott E. Kasner

“…Here we aimed to assess the association between pharmacologic inhibition of angiotensin‐converting enzyme and subsequent nontraumatic SAH. …”
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Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates by Panagiotis N. Lalagkas, Rachel D. Melamed

“…Drug repurposing can accelerate improvements to care, as FDA-approved drugs have known safety and pharmacological profiles. Some drugs for other conditions, such as metformin, an antidiabetic, have been tested in clinical trials for repurposing for breast cancer. …”
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The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer by XiaoJun Duan, Rihan Wu, Mingyang Zhang, Kexin Li, Lei Yu, Huirong Sun, Xingxia Hao, Changshan Wang

“…Abstract NOTCH1 signaling, a vital regulator of cell proliferation and differentiation, is widely involved in the occurrence and development of malignant tumors. Pharmacological regulation of NOTCH1 is promising in tumor immunotherapy, whereas the effective rate of existing therapies remains low. …”
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Diabetes Management and Outcomes among Patients with Type 2 Diabetes Attending a Renal Service by Elizabeth Skalkos, Rohit Rajagopal, David Simmons

“…Patients with comorbid type 2 diabetes mellitus (T2DM) and renal disease, particularly those treated with insulin, often require complex pharmacological treatment and management of other diabetes complications. …”
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Сomparative analysis of wild and cultivated Lathyrus L. spp. according to their primary and secondary metabolite contents by A. E. Solovyeva, T. V. Shelenga, А. L. Shavarda, M. O. Burlyaeva

“…In view of the above,  our goal was to analyze organic  acids, free amino  acids and secondary metabolites in green biomass  of Lathyrus to facilitate comprehensive assessment of its forage  and  pharmacological value. We analyzed 32 accessions  of Lathyrus sativus L., L. tuberosus L., L. sylvestris L., L. vernus (L.) …”
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Efficacy and Safety of Murivenna Anal Infiltration Compared to Diltiazem Topical Application in Chronic Anal Fissure: Protocol for a Prospective, Randomized, Open-Label Clinical Tr... by Pratap Shankar KM, Indu Puthan Purayil, Palengara Binitha, Amit Kumar Rai, Sophia Jameela, Azeem Ahmad, Chandra Sekhara Rao Bhogavalli, Narayanam Srikanth, Rabinarayan Acharya

“…There are various treatment options for anal fissure, ranging from pharmacological agents that reduce anal sphincter tone to surgical interventions for cases resistant to medical management. …”
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Effect of meta-Topolin on morphological, physiochemical, and molecular dynamics during in vitro regeneration of Salix tetrasperma Roxb. by Zubair Altaf Reshi, Fohad Mabood Husain, Mehrun Nisha Khanam, Saad Bin Javed

“…The GC-MS analysis from leaf extracts of donor plants and in vitro derived plantlets has revealed a broad spectrum of phytochemical compounds with significant pharmacological properties. No polymorphism in the banding pattern was found when the genetic fidelity of the regenerated plants was evaluated using SCoT primers, indicating the clonal stability of micropropagated plants. …”
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The miR-23a/27a/24 − 2 cluster drives immune evasion and resistance to PD-1/PD-L1 blockade in non-small cell lung cancer by Hao Luo, Bin Hu, Xiang-Rong Gu, Jing Chen, Xiao-Qing Fan, Wei Zhang, Ren-Tao Wang, Xian-Dong He, Wei Guo, Nan Dai, Dan Jian, Qing Li, Cheng-Xiong Xu, Hua Jin

“…In addition, we demonstrated that the expression of the miR-23a/27a/24 − 2 cluster of miRNAs is maintained in NSCLC through increased Wnt/β-catenin signaling-regulated interaction of transcription factor 4 (TCF4) and the miR-23a/27a/24 − 2 cluster promoter. Notably, pharmacologic targeting of the eIF3B pathway dramatically increased sensitivity to PD-1/PD-L1 blockade in patients with high expression of the miR-23a/27a/24 − 2 cluster in NSCLC. …”
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Artrosis: ¿cambios degenerativos o cambios adaptativos? Consejos educativos breves en la consulta de atención primaria by Gema Izquierdo Enríquez, María Victoria García Espinosa, Isabel Prieto Checa, María Fernández de Paúl, Patricia Moreno Carrero, Silvia Fernanda García Vila

“…Moreover, there are no disease-modifying drugs or curative treatment at present; the basic or first-line treatment is non-pharmacological, based on education and physical exercise.The presence of degenerative changes in imaging tests is present in a high percentage of the general asymptomatic population, i.e. in those who have no pain or functional limitation, and this percentage increases progressively with age. …”
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Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies by Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk

“…Considering the promising pharmacological potential of this compound and using spectroscopic techniques, HSA and human serum albumin nanoparticles (HSA-NP) were tested as carriers of this molecule. …”
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Emotion dysregulation and impulsivity as overlapping symptoms in adult Attention-Deficit/Hyperactivity Disorder and Borderline Personality Disorder: severity profiles and associati... by Eszter Kenézlői, Lívia Balogh, Szilvia Somogyi, Evelyn E. Lévay, Zsuzsa Halmai, Zsófia Nemoda, Zsolt S. Unoka, János M. Réthelyi

“…These findings have various clinical implications for the treatment of aADHD and BPD, including psychoeducation, pharmacological interventions, and psychotherapy targeting specific symptom domains.…”
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ERK1/2 Inhibition Alleviates Diabetic Cardiomyopathy by Suppressing Fatty Acid Metabolism by Erin McLean, Caroline De Roo, Annabel Maag, Megan Coble, Jefferson Cano, Ruijie Liu

“…In this study, we tested our hypothesis that pharmacological inhibition of ERK1/2 alleviates cardiac remodeling in diabetic mice through a reduction in fatty acid metabolism. …”
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Effect of comprehensive nursing interventions on relieving postoperative pain of breast cancer patients (乳腺肿瘤患者术后疼痛的护理干预研究) by LI Weijia (李唯佳), LI Yueru (李月茹), LI Ning (李宁), CAO Hongjing (曹红京)

“…All patients received routine nursing and pharmacologic treatment for postoperative pain, and those in the study group were given comprehensive interventions such as basic nursing, psychological nursing and positioning nursing. …”
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