Effect of floral therapy in mothers of premature newborns: A randomized controlled trial by Tatiana Carneiro de Resende, Karla Oliveira Marcacine, Erika de Sá Vieira Abuchaim, Marcia Barbieri, Maria Cristina Gabrielloni, Ana Cristina Freitas de Vilhena Abrão

“…Conclusions: The use of the Five-Flower essence as a non-pharmacological therapy is effective in reducing the stress and cortisol levels in mothers of premature newborns admitted to neonatal and semi-intensive care units.…”
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Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction by Irene López-Ferreruela, Sara Malo, Blanca Obón-Azuara, María José Rabanaque, Adriana Gamba, Sara Castel-Feced, Isabel Aguilar-Palacio

“…The existence of gender differences in pharmacological treatment after an AMI has been described. …”
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Exploring Medicinal Plants for Antimicrobial Activity and Synergistic Effects With Doxycycline Against Bacterial Species by Joel Frank Kenmeni, Ibrahim Sifi, Borel Ndezo Bisso, Prudence Ngalula Kayoka-Kabongo, Ulrich Joël Tsopmene, Jean Paul Dzoyem

“…Medicinal plants are rich sources of bioactive compounds with diverse pharmacological properties, including antimicrobial activities. …”
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In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms by Elshahat A. Toson, Amira A. El-Fallal, Marwa A. Oransa, Hoda M. El-Gharabawy

“…Abstract Ganoderma mushrooms have a variety of pharmacological activities and may have antitumor effects. …”
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Are changes in pain intensity related to changes in balance control in individuals with chronic non-specific low back pain? A systematic review and meta-analysis by Daniel K.Y. Zheng, Jae Q.J. Liu, Jeremy R. Chang, Jeffrey C.Y. Ng, Zhixing Zhou, Jinlong Wu, Chelsia K.C. Cheung, Frank F. Huang, Sabina M. Pinto, Dino Samartzis, Manuela L. Ferreira, Kanchana Ekanayake, Stephen Lord, Xueqiang Wang, Arnold Y.L. Wong

“…Two reviewers independently screened and identified relevant studies that investigated the effects of non-surgical or non-pharmacological CNSLBP treatments on both pain intensity and balance control. …”
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PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

“…Much of this information is contained in toxicology reports, which summarise the results of animal studies designed to analyse the effects of the tested compound, including unintended pharmacological and toxic effects, known as treatment-related findings. …”
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New epigenome players in the regulation of PCSK9-H3K4me3 and H3K9ac alterations by statin in hypercholesterolemia by Sushmitha Duddu, Yash T. Katakia, Rituparna Chakrabarti, Pooja Sharma, Praphulla Chandra Shukla

“…Similarly, in mice fed a high-fat diet, ATS showed increased levels of H3K4me3 and H3K9ac in the liver. Furthermore, a pharmacological intervention that inhibits the H3K4me3 and H3K9ac enrichment resulted in the reversal of statin-induced upregulation of PCSK9. …”
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Efficacy and safety of intravenous ferric carboxymaltose in the treatment of Restless Legs Syndrome: a systematic review and meta-analysis by Ayesha Khan, Harsh Kumar, Kuldeep Dalpat Rai, Anzel Saeed, Jawad Ishtiaq, Muhammad Tanveer Alam, Sakshi Chawla, Md Ariful Haque, Md Ariful Haque

“…RLS is treated using various pharmacological options, including dopamine agonists, benzodiazepines, anticonvulsants, opioids, and bupropion. …”
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Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy by Patrizia Murer, Barbara Brannetti, Jean-Michel Rondeau, Laetitia Petersen, Nicole Egli, Simone Popp, Catherine Regnier, Kirsten Richter, Andreas Katopodis, Christoph Huber

“…Optimization of the selectivity and pharmacological properties led to the selection of ANV419. …”
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Linking altered neuronal and synaptic properties to nicotinic receptor Alpha5 subunit gene dysfunction: a translational investigation in rat mPFC and human cortical layer 6 by Danqing Yang, Guanxiao Qi, Daniel Delev, Uwe Maskos, Dirk Feldmeyer

“…They highlight a potential pharmacological target for restoring the relevant behavioral output.…”
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Focus on Depression in Parkinson’s Disease: A Delphi Consensus of Experts in Psychiatry, Neurology, and Geriatrics by Luis Agüera-Ortiz, Rocío García-Ramos, Francisco J. Grandas Pérez, Jorge López-Álvarez, José Manuel Montes Rodríguez, F. Javier Olazarán Rodríguez, Javier Olivera Pueyo, Carmelo Pelegrín Valero, Jesús Porta-Etessam

“…Efficacious and well-tolerated pharmacological options for Parkinson’s comorbid depression were selective serotonin reuptake inhibitors (especially sertraline), dual-action serotonin and norepinephrine reuptake inhibitors (venlafaxine, desvenlafaxine, and duloxetine), multimodal (vortioxetine, bupropion, mirtazapine, and tianeptine), and anti-Parkinsonian dopamine agonists (pramipexole, ropinirole, and rotigotine). …”
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Effect of Tai Chi combined with music therapy on the cognitive function in older adult individuals with mild cognitive impairment by Chunhui Zhou

“…This combined intervention is more effective than Tai Chi alone, highlighting its potential as a non-pharmacological approach to enhance cognitive health in the aging population.…”
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Current update on surgical management for spinal tuberculosis: a scientific mapping of worldwide publications by Romaniyanto Romaniyanto, Muhana Fawwazy Ilyas, Aldebaran Lado, Daffa Sadewa, Daffa Sadewa, Dykall Naf'an Dzikri, Enrico Ananda Budiono, Enrico Ananda Budiono

“…Key topics evolved from basic surgical methods, including early spinal procedures, to integrating pharmacological approaches alongside surgical techniques, such as antitubercular drugs, advancing into imaging research and procedure research involving refined surgical methods like spinal fusion. …”
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Study on the Fingerprint Spectrum and the Spectrum-Effect Relationship of Analgesic and Anti-Inflammatory Effects of the Aqueous Extract from Dalbergia hancai Benth by Qin Qiu, Xiaofang Liu, Chunying Huang, Yanling Guo, Dandan Zhen, Junhao Shi, Baojun Gu, Hanshen Zhen, Miao Zhang

“…Simultaneously, it has been included in the “Quality Standard of Zhuang medicine in Guangxi Zhuang Autonomous Region (Vol. 2)” and possessed outstanding pharmacological effects. However, the pharmacodynamic material basis of D. hancai still remains unclear. …”
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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…IntroductionThe global health challenge of ulcerative colitis (UC) has been classified by the WHO as a modern refractory disease, commonly referred to as green cancer, with limited treatment options still available, highlighting the urgent need for the development of new therapeutic strategies. Recent pharmacological research has shown that traditional Chinese medicine saussurea costus (SC) possesses beneficial antibacterial and anti-inflammatory properties. …”
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Eating "rubbish"? Exploring the herbal secrets of "Laji-He," a traditional herbal rice snack from southern China by Renchuan Hu, Qianyun Wang, Zhongxin Duan, Yunan Hu, Kedao Lai, Xiaohui Cai, Ya Peng, Binsheng Luo

“…Additionally, the medicinal properties of these plants were categorized based on traditional Chinese medicinal theory and modern pharmacological literature. A detailed review of historical texts and local chronicles was also performed to trace the historical development and cultural changes of Laji-He. …”
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Impact of Treatment on Rate of Biphasic Reaction in Children with Anaphylaxis by William Bonadio, Connor Welsh, Brad Pradarelli, Yunfai Ng

“…Objective: Our goal was to characterize a large group of children presenting to the emergency department (ED) with acute anaphylaxis, treated with intramuscular epinephrine (IM EPI) and a corticosteroid (CS), and to determine the impact of pharmacologic intervention on the rate and timing of biphasic reactions (BPR). …”
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Green treasures: phytochemical screening and antioxidant potential of freshwater species of Oedogonium, Ulothrix and Mougeotia (Chlorophyceae) by Elsa Shibu Sruthy, Edathiruthi Kottukkal Chandran Baiju

“…Natural antioxidant compounds from plants can contribute to pharmacological activities by neutralizing free radicals. …”
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House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model by Patricia Ramos-Ramírez, Jielu Liu, Sofia Mogren, Joshua Gregory, Malin Noreby, Anne Petrén, Ying Lei, Henric Olsson, Marianne van Hage, Jukka Kervinen, Lars Hellman, Cecilia Andersson, Gunnar Nilsson, Mikael Adner

“…As guinea pigs exhibit anatomical, physiological, and pharmacological features resembling human airways, including mast cell distribution and mediator release, we evaluated the effect of extracts from two common allergens, house dust mite (HDM) and cat dander (CDE), on histopathological changes and the composition of tryptase- and chymase-positive mast cells in the guinea pig lungs. …”
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CCN3: lactational bone booster by Nathan Xu, Kyle Yang, Mengjie Wang

“…Using a comprehensive set of parabiosis coupled with in vivo µCT, bone transplant studies, cell culturing and differentiation assays, mouse genetic models, pharmacologic interventions, hepatic viral transduction, and sequencing analysis, a recent study discovered that cellular communication network factor 3 (CCN3), derived from ARHERα/Kiss1 neurons, functions as an osteogenic hormone to sustain bone formation and progeny survival during lactation. …”
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