Showing 5,021 - 5,040 results of 5,497 for search '"Pharmacology"', query time: 0.09s Refine Results
  1. 5021

    Selective mPGES-1 Inhibitor Ameliorated Adjuvant-Induced Arthritis in the Rat Model by Min Ji Kim, Hwi-Ho Lee, Choi Kim, Ja Yeon Lee, Kyung-Sook Chung, Kyung-Tae Lee, Jae Yeol Lee

    Published 2024-01-01
    “…Therefore, MPO-0144 represents a valuable pharmacological tool for the study of regulation of inducible mPGES-1 in an inflammatory arthritis rat model.…”
    Get full text
    Article
  2. 5022

    Research protocol for a systematic review and meta-analysis of the effects of music on anxiety and physiological outcomes in patients undergoing bronchoscopy. by Amani Kacem, Dhekra Chebil, Sana Aissa, Anis Maatallah, Ahmed Abdelghani

    Published 2025-01-01
    “…<h4>Conclusion</h4>The systematic review produced from this protocol will provide evidence on the effectiveness of music for patients undergoing bronchoscopy and will contribute to strengthening the existing body of knowledge on non-pharmacological interventions for anxiety management during medical procedures.…”
    Get full text
    Article
  3. 5023

    Effects of Anti-Obesity Strategies on Bone Mineral Density: A Comprehensive Meta-Analysis of Randomized Controlled Trials by Myung Jin Kim, Seonok Kim, Han Na Jung, Chang Hee Jung, Woo Je Lee, Yun Kyung Cho

    Published 2025-01-01
    “…At follow-up examination, the BMD of the lumbar spine decreased significantly after metabolic surgery (mean difference [MD]=-0.40 g/cm2; 95% confidence interval [CI], -0.73 to -0.07; I2=0%); lifestyle and pharmacological interventions did not result in a significant decrease in BMD at any location. …”
    Get full text
    Article
  4. 5024

    Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells by Hyun-Jae Jang, Kang-Hoon Kim, Eun-Jae Park, Jeong A. Kang, Bong-Sik Yun, Seung-Jae Lee, Chan Sun Park, Soyoung Lee, Seung Woong Lee, Mun-Chual Rho

    Published 2020-01-01
    “…Although various pharmacological studies of C. orbiculatus extract has been reported, an anti-inflammatory mechanism study of their phytochemical constituents has not been fully elucidated. …”
    Get full text
    Article
  5. 5025

    Protective Effect of Shenfu Injection against Sepsis-induced Acute Lung Injury by Suppressing Inflammation and Apoptosis Through the Regulation of the Janus Kinase 2/Signal Transdu... by Li-Juan Cao, Hai-Tang Xie, Zhong-Xia Chu, Yue Ma, Ming-Ming Wang, Shi Zhuang

    Published 2024-12-01
    “…Shenfu injection (SFI) is a Chinese herbal medicine extracted from red ginseng and Aconite, Radix Aconiti, with various pharmacological activities. This study aimed to investigate the potential mechanism of action of SFI in preventing sepsis-induced ALI. …”
    Get full text
    Article
  6. 5026

    Relationship between secondary metabolites and ecological suitability zones for Eucommia ulmoides. by Ting Yao, Ya Wang, Na Zhang, Beichao Wang, Zhuoting Gan

    Published 2025-01-01
    “…The contents of six pharmacologically active secondary metabolites, including chlorogenic acid, aucubin, geniposidic acid, geniposide, pinoresinol monoglucoside, and pinoresinol diglucoside were measured in the EU bark. …”
    Get full text
    Article
  7. 5027

    Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist P... by Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw

    Published 2014-01-01
    “…Using a preconstricted preparation of rat tail arterial smooth muscle, a single dose of 10−6 M of the peptide effectively inhibited the dose-dependent relaxation effect of bradykinin between 10−11 M and 10−5 M and subsequently, this effect was pharmacologically-characterized using specific bradykinin B1- (desArg-HOE140) and B2-receptor (HOE140) antagonists; the data from which demonstrated that the antagonism of the novel peptide was mediated through B2-receptors. …”
    Get full text
    Article
  8. 5028

    Diabetic microangiopathies: mechanisms of development, approaches to the therapy by Birukova E.V, Shinkin M.V.

    Published 2018-07-01
    “…<br> Calcium dobesilate refers to the pharmacological group of angioprotectors and microcirculatory correctors.…”
    Get full text
    Article
  9. 5029

    Phylogenetic Analysis and Extracellular Enzyme Profiles of Yeast Strains Isolated from Raspberry Fruits by Melih Günay, Tulay Turgut Genc

    Published 2021-03-01
    “…Raspberry fruit contains phenolic compounds, flavones, flavonoids, vitamins, and antioxidant substances that are important properties for health and pharmacological sciences. Edible berries provide also a suitable habitat for the growth of various microorganisms. …”
    Get full text
    Article
  10. 5030

    The Effects of Six Weeks of Patella Taping on Function, Proprioception, and Balance in Women with Knee Osteoarthritis by Maryam Alikhani, Hamid Tabatabai

    Published 2024-11-01
    “…Patella taping may be an effective non-pharmacological tool for enhancing these outcomes and is recommended for use by sports trainers and physiotherapists.…”
    Get full text
    Article
  11. 5031

    Alcohol Misuse and Alcohol Use Disorder in Adolescents by İpek Süzer Gamlı, Mehmet Can Erata

    Published 2024-12-01
    “…Family therapy, particularly multidimensional family therapy, has proven to be highly effective. While pharmacological options exist, such as disulfiram and naltrexone, their use is limited and requires careful monitoring due to potential risks. …”
    Get full text
    Article
  12. 5032

    Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice by Dong Han, Jue Wang, Lulu Wen, Miao Sun, Hang Liu, Yan Gao

    Published 2021-01-01
    “…Our results reveal pharmacological effect of RIPC in promoting microglia/macrophage transferring from M1 to M2 phenotype after MCAO/R in mice, which provides theoretical support for the therapeutic effect of RIPC in ischemic stroke.…”
    Get full text
    Article
  13. 5033

    Antihyperglycemic Potential of Dried Powder Combination of Hygrophila auriculata and Cordia macleodii: In Vivo Study in Sprague Dawley Rats by Farooq M. Almutairi

    Published 2024-12-01
    “…A key role in modulating the pharmacological action is played by the components derived from plants, including alkaloids and flavonoids. …”
    Get full text
    Article
  14. 5034

    Enhancing immunotherapy efficacy with synergistic low-dose radiation in metastatic melanoma: current insights and prospects by Zahid Rafiq, Mingyo Kang, Hampartsoum B. Barsoumian, Gohar S. Manzar, Yun Hu, Carola Leuschner, Ailing Huang, Fatemeh Masrorpour, Weiqin Lu, Nahum Puebla-Osorio, James W. Welsh

    Published 2025-01-01
    “…Furthermore, we explore the challenges associated with LDRT’s integration into combination therapies, addressing crucial factors such as optimal dosage, fractionation, treatment frequency, and synergy with other pharmacological agents. Considering its low toxicity profile, LDRT presents a compelling case for application across multiple lesions, augmenting the antitumor immune response in poly-metastatic disease scenarios. …”
    Get full text
    Article
  15. 5035

    Exercise training and chronic kidney disease: characterization and bibliometrics of citation classics of clinical intervention trials by Fan Zhang, Shan Liu, Yan Bai, Liuyan Huang, Yifei Zhong, Yi Li

    Published 2024-12-01
    “…Reported dropout rates ranged from 0.0% to 47.4%.Conclusion A bibliometric analysis of citation classics on exercise training and CKD highlights the potential benefits of exercise as a non-pharmacological therapy for patients with CKD, as well as developments and hotspots in the field.…”
    Get full text
    Article
  16. 5036

    Post-chemoradiotherapy adjuvant chemotherapy of rectal cancer by E. V. Ledin, A. V. Kochatkov

    Published 2018-08-01
    “…To present the analysis of available data on approach to pharmacological antineoplastic therapy at rectal cancer (RC) after chemoradiotherapy followed by surgical treatment, as well as within the «watch & wait» concept. …”
    Get full text
    Article
  17. 5037

    Attenuation of Myocardial Injury by HMGB1 Blockade during Ischemia/Reperfusion Is Toll-Like Receptor 2-Dependent by Jan Mersmann, Franziska Iskandar, Kathrina Latsch, Katharina Habeck, Vera Sprunck, René Zimmermann, Ralf R. Schumann, Kai Zacharowski, Alexander Koch

    Published 2013-01-01
    “…Genetic or pharmacological ablation of toll-like receptor 2 (TLR2) protects against myocardial ischemia/reperfusion injury (MI/R). …”
    Get full text
    Article
  18. 5038

    Current treatment modalities for dry eye disease by E.B. Tatarnikova, O.I. Krivosheina

    Published 2021-03-01
    “…These data are required for the understanding of the pharmacological effects of various drug classes prescribed for DED and early treatment initiation.…”
    Get full text
    Article
  19. 5039

    Phenobarbital as an adjunctive agent for sedation in pediatric intensive care unit patients: A single-center, retrospective study from Colorado by Kelli Jo Welter, Mackenzie N. DeVine, Sharon E. Gordon, Gina Demasellis

    Published 2024-09-01
    “…Background: Pediatric patients require pharmacological management of pain and agitation associated with mechanical ventilation. …”
    Get full text
    Article
  20. 5040

    “Lung-on-a-chip” as an instrument for studying the pathophysiology of human respiration by Oksana A. Zhukova, Iuliia V. Ozerskaya, Dmitry V. Basmanov, Vsevolod Yu. Stolyarov, Vladimir G. Bogush, Vladimir V. Kolesov, Kirill A. Zykov, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev

    Published 2024-12-01
    “…“Lung-on-a-chip” (LoC) is a microfluidic device, imitating the gas-fluid interface of the pulmonary alveole in the human lung and intended for pathophysiological, pharmacological and molecular-biological studies of the air-blood barrier in vitro. …”
    Get full text
    Article