From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

“…By integrating traditional medicinal knowledge with modern scientific insights, this review underscores L. barbarum’s potential as a functional food and therapeutic agent. Its unique pharmacological properties and broad applicability position it as a valuable tool for health promotion and disease prevention, while highlighting areas requiring further research to optimise its safe and effective use.…”
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Upper Extremity Superficial Vein Thromboses Presenting as Acute Neck Pain in a Young and Healthy Male: A Case Report by Kristen L Zosel, Max K Dummar, Benjamin G Adams, Nancy C Henderson, Richard B Westrick

“… # Outcomes The subject underwent a D-dimer, Doppler ultrasound, pharmacological treatment of Rivaroxaban, and was referred to hematology/oncology to rule out systemic causes of SVTs. …”
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General views on treatment technologies for patients with incisional ventral hernia by E. E. Lukoyanychev, S. G. Izmajlov, V. A. Emelyanov, O. S. Kolchina, A. I. Rotkov, M. N. Kiselyov

“…The introduction of new methods of hernia repair based on the uncontrolled separation of the anatomical structures of the abdominal wall imposes special requirements on surgical technology: plastic material, instrumental and technical support, wound closure and pharmacological support, especially in conditions of increased intra-abdominal pressure and tissue tension. …”
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Glypican-3 is a key tuner of the Hedgehog pathway in COPD by Laure M.G. Petit, Lynda Saber Cherif, Maëva A. Devilliers, Sarah Hatoum, Julien Ancel, Gonzague Delepine, Anne Durlach, Xavier Dubernard, Jean-Claude Mérol, Christophe Ruaux, Myriam Polette, Gaëtan Deslée, Jeanne-Marie Perotin, Valérian Dormoy

“…The localisation of GPC3 was evaluated through immunofluorescent stainings on isolated bronchial AEC and tissues from non-COPD and COPD patients. GPC3 pharmacological modulation was achieved with Codrituzumab during AEC differentiation. …”
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BLOOD PRESSURE CONTROL WITH BENSON RELAXATION TECHNIQUE IN HYPERTENSIVE PATIENTS by Dwi Yuniar Ramadhani, Dinda Rahma Annisa, Putri Nabila Savira Suwandi, Ulan Apriani, Diah Qurrotul Aini, Anggi Zubatian Artha Dinata

“…Efforts that may be made to control blood pressure and avoid depression can be done by using non-pharmacological techniques, one of which is by using relaxation techniques. …”
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Effect of Matrine on growth performance, gut health, and gut microbiota in chickens infected with avian pathogenic Escherichia coli by Ningning Mao, Yaming Yu, Jiqin Cui, Jin He, Yang Yang, Deyun Wang

“…Matrine, a natural component derived from Sophora flavescens, exhibits various pharmacological effects, including anti-inflammatory and antioxidant activities. …”
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Management of a Female Patient with Irritable Bowel Syndrome and Somatoform Disorder by E. A. Trush, E. A. Poluektova, A. G. Beniashvili, O. S. Shifrin

“…Kolofort can be the drug of choice both in patients with IBS and the pharmacological part of therapy in patients with somatization disorder.…”
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Antimicrobial resistance of <I>Salmonella</I> isolates recovered from animal products by N. B. Shadrova, O. V. Pruntova, E. A. Korchagina

“…Different Salmonella serovars demonstrated different proportions of susceptible and resistant isolates, in terms of antibiotics from ten pharmacological groups. The largest number of polyresistant isolates was noted in Salmonella serovars S. virchow, S. nigeria, S. infantis, S. colindale. …”
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Nanonization of ethanolic tulsi leaf extract and its major compound eugenol and evaluation of their inhibitory potential against calcium oxalate crystal (a kidney stone component) by Sourav Ghosh, Tarakdas Basu

“…., bare TLE and eugenol; ENP was more potent than TLE-NP with respect to crystallization inhibitory activity, whereas they were comparable in crystal disintegration potency. Future in vivo pharmacological and toxicological studies will surely lead to the development of the TLE-NPs and ENPs as potential therapeutic agents against calcium oxalate pathogenesis.…”
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High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein by Xin Zhang, Hui Chen, Hui Lin, Ronglan Wen, Fan Yang

“…As a consequence of using specific pharmacological, physiological, and ADMET criteria, four new prevailing compounds, NPA000018, NPA000111, NPA00305, and NPA014826, were successfully selected. …”
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Calculation of the molecular properties of five cephalosporins: cephradine, cephalexin, cefadroxil, cefprozil and ceftobiprole by Elso Manuel Cruz Cruz, Eslhey María Sánchez Domínguez

“…<strong>Background:</strong> The side chains attached to the 7-amino cephalosporanic acid, the structural basis of cephalosporin, condition its molecular properties and cause differences in its pharmacological action. Molecular modeling contributes to further knowledge about this relationship. …”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Methods Here, we investigated the potential of Dioscin, a natural compound known for its diverse pharmacological properties, in mitigating ferroptosis in cardiomyocytes following MI by targeting ER stress. …”
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RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection by Ignacio Silva-Llanes, Ignacio Silva-Llanes, Ignacio Silva-Llanes, Enrique Madruga, Enrique Madruga, Ana Martínez, Ana Martínez, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker

“…One of the main challenges of these diseases is that they have neither biomarkers nor pharmacological targets to stop the neurodegenerative process. …”
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Rheumatoid-like hand deformities and aortic valve disease in a 13-year-old girl with homozygous familial hypercholesterolemia: a case report by Anjuman Ara Rahman, Abhijit Datta, Kamal Uddin Ahmed, Anindita Das Barshan, Mohammad Jahid Hasan

“…Early detection allows timely intervention, such as lifestyle modifications and pharmacological treatments, which can significantly reduce these risks. …”
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Comparative Analysis of the Content of Sum of Hydroxycinnamic Acids from Leaves of Actinidia arguta Lindl. Collected in Ukraine and China by Nadiia Kovalska, Uliana Karpiuk, Valentyna Minarchenko, Iryna Cholak, Natalia Zaimenko, Nadiia Skrypchenko, Dejiang Liu

“…Hydroxycinnamic acids (HCAs) are one of the important biologically active substances of A. arguta leaves, which provide the pharmacological action of this raw material. The aim of the study was to identify and compare the quantitative content of HCAs in the leaves of A. arguta harvested in Ukraine and China in different phases of the growing season. …”
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Genome-wide identification of the bHLH gene family in Scutellaria baicalensis and their relationship with baicalin biosynthesis under drought stress by Yingxin Sun, Beier Wang, Lichao Zhang, Xiaohan Zheng, Peng Xu, Meng Zhang, Meiguang Han, Peng Di, Mei Han, Lin Cheng, Limin Yang

“…The bHLH gene family plays a critical role in regulating internal responses in plants. Although the pharmacological properties of Scutellaria baicalensis have been extensively studied, its bHLH gene family remains poorly investigated. …”
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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

“…This review elucidates the pharmacological mechanisms underlying the protective effects of wogonin in CNS diseases, including ischemic stroke, hemorrhagic stroke, traumatic brain injury, epilepsy, anxiety, neurodegenerative diseases, and CNS infections. …”
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Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity by Krishma Tailor, Krishma Tailor, Janine van Ree, Timothy Stowe, Brit Ventura, Connor Sisk, Joanna Courtis, Anna Camp, Fatima Elzamzami, Jan van Deursen, Robert O’Brien, Jeffrey Baron, Julian C. Lui

“…Taken together, our findings provide further evidence that cartilage-targeted therapy could provide new pharmacological approaches for the treatment of childhood growth disorders, such as GH-insensitivity syndrome.…”
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Diagnosis and Treatment of Golfer's Elbow: A Review of Therapeutic Approaches by Karol Dzwonnik, Urszula Zelik, Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Wiktoria Domino, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“…Conservative treatment, including rest, physical therapy, and pharmacological support, is the first-line approach. In refractory cases, surgical options like open repair and arthroscopy, along with innovative techniques such as collagen-augmented sutures and stem cell applications, show promising results. …”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2007 Update by Denis E O’Donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy D Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Alan Kaplan, Sean Keenan, Yves Lacasse, Francois Maltais, Jeremy Road, Graeme Rocker, Don Sin, Tasmin Sinuff, Nha Voduc

“…Highlights of this update include new epidemiological information on mortality and prevalence of COPD, which charts its emergence as a major health problem for women; a new section on common comorbidities in COPD; an increased emphasis on the meaningful benefits of combined pharmacological and nonpharmacological therapies; and a new discussion on the prevention of acute exacerbations. …”
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