Longevity Recipe - Lifestyle Influences on the Quantity and Quality of Life by Katarzyna Piotrowicz, Hubert Piotrowicz, Jacek Kurzeja, Agnieszka Bajkacz, Wojciech Kraśnik, Olga Jankowska, Anna Rogala, Joanna Osmólska

“…A search is underway for anti-aging pharmacological compounds that are both efficacious and safe. …”
Get full text

Chlorhexidine cytotoxicity on oral Behaviors: Last 20 Years systematic review by Luca Fiorillo, Cesare D'Amico, Vini Mehta, Marco Cicciù, Gabriele Cervino

“…Objectives: Modern dentistry has made available a series of cariostatic pharmacological products with beneficial positive effects on oral health. …”
Get full text

Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…Moreover, there are different strategies that used by researchers and pharmacological companies to develop vaccines including attenuated or killed viruses, RNA of a spike protein, and vector expressing a particular protein of the virus. …”
Get full text

Hypertrophic cardiomyopathy: insights into pathophysiology and novel therapeutic strategies from clinical studies by Samuel Oluwadare Olalekan, Olalekan Olanrewaju Bakare, Patrick Godwin Okwute, Ifabunmi Oduyemi Osonuga, Muinat Moronke Adeyanju, Victoria Biola Edema

“…Recent advances in therapeutic strategies, including novel pharmacological agents like mavacamten and aficamten, were examined for their potential to help patients manage the disease and lead more accommodating lifestyles. …”
Get full text

Comparative Quantitative Study on Phytochemical Contents and Antioxidant Activities of Capsicum annuum L. and Capsicum frutescens L. by Tomi Lois Olatunji, Anthony Jide Afolayan

“…Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable parental genotypes in breeding for nutritional and pharmacological purposes.…”
Get full text

Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2 by Brigitta Buttari, Antonella Tramutola, Ana I. Rojo, Niki Chondrogianni, Sarmistha Saha, Alessandra Berry, Letizia Giona, Joana P. Miranda, Elisabetta Profumo, Sergio Davinelli, Andreas Daiber, Antonio Cuadrado, Fabio Di Domenico

“…Given NRF2’s role in mitigating proteotoxic stress, the pharmacological modulation of NRF2 has emerged as a promising therapeutic strategy, even in aged preclinical models. …”
Get full text

Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy by Sally L. Elshaer, Mohammed A. Abdelsaid, Ahmad Al-Azayzih, Parag Kumar, Suraporn Matragoon, Julian J. Nussbaum, Azza B. El-Remessy

“…Additional cultures were treated with mutant-proNGF in the presence of specific pharmacological inhibitors of TrkA and p75NTR receptors. …”
Get full text

Mathematical modeling and QSPR analysis of hepatitis treatment drugs through connection indices an innovative approach by Khalil Hadi Hakami, Abdul Rauf Khan, Muhammad Ali

“…This work conducts QSPR analysis to obtain the most accurate approximations for the physico-chemical attributes of pharmacological agents employed in the treatment of hepatitis.…”
Get full text

A novel glucan from Sparassis latifolia: purification, structural characterization and protective effect on gastric mucosal cells against ethanol-induced damage by Mengyu Wang, Guoying Lv, Ruimeng Zhao, Weiming Cai, Zuofa Zhang

“…Abstract Sparassis latifolia is a rare edible mushroom with many pharmacological activities. Active screening found that the crude polysaccharide from this mushroom (SLP) exhibited noticeable gastroprotective effects. …”
Get full text

Mental Disorders in Children and Adolescents in Crisis Situations: The Impact of the COVID-19 Pandemic and Armed Conflicts - Types of Disorders, Effects, and Intervention Strategie... by Katarzyna Gadżała, Sabina Przygodzka, Maciej Rutkiewicz, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…Support for young patients, psychological and pharmacological interventions and raising awareness about the importance of mental health are the basis for improving the mental health of adolescents. …”
Get full text

Vitamin D sensitizes cervical cancer to radiation-induced apoptosis by inhibiting autophagy through degradation of Ambra1 by Zhaoming zhang, Xinyue Yu, Guanghui Cheng

“…Importantly, the pharmacological inhibition of caspases or the Ambra1 overexpression could restore tumor proliferation under the vitamin D and radiation combination treatment. …”
Get full text

Optimization of betulinic and ursolic acids and phenolics extraction from endemic Rosa pisiformis using Box-Behnken design in relation to cytotoxic activities by Hatice Demiray, Mesut Emir Dibek, Onur Özel

“…Abstract Despite its important pharmacological bioactivities, betulinic acid is still primarily obtained through extraction from heartwood and bark or synthesized synthetically, with less than 3% efficiency. …”
Get full text

Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina) by Gregory Scott, Meghan M. Louis, Julie A. Balko, Claire M. Bublitz, Brigid V. Troan, Ronald E. Baynes, Dustin Smith, Larry J. Minter

“…Transdermal administration is an important method of pharmacologic drug therapy in amphibians, made possible by their unique skin physiology and permeability. …”
Get full text

Antimicrobial Potential and Free Radical Scavenging Activity of Sesbania grandiflora (Linn.) Pres. Flowers in Three Different Solvents by Surabhi Ambastha, Amit Patnaik, Vinay Oraon, Latika Sharan

“…Almost every part of this plant possesses pharmacological activities. The present investigation focused on antimicrobial potential and the antioxidant capacity of this plant flowers in three different solvent extracts such as methanol, acetone, and water.Methods:Cold excerpt method is used for the preparation of the extract. …”
Get full text

XXIX Expert Advisory Board of the Russian Glaucoma Society, the XII meeting of the International Expert Advisory Board on glaucoma issues by A.V. Seleznev

“…New approaches to the diagnosis and treatment of this disease, aimed at personalizing strategic and tactical measures, an emergence of new pharmacological preparations and innovative surgical techniques on the market were considered by the Advisory Board. …”
Get full text

Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity by Linzi Li, Xueying Lei, Lin Chen, Ya Ma, Jun Luo, Xuebo Liu, Xinglian Xu, Guanghong Zhou, Xianchao Feng

“…Quercetin compounds have antioxidant, anti-inflammatory and anticancer pharmacological functions. Long-term exposure to acrylamide (AA) can cause liver injury and endanger human health. …”
Get full text

Effects of Seed Priming with Zinc Sulfate on Nutritional Enrichment and Biochemical Fingerprints of Momordica charantia by Shazia Anwer Bukhari, Nabila Farah, Saqib Mahmood, Javaria Altaf, Ghulam Mustafa

“…Momordica charantia is an economically important medicinal plant reported for a range of pharmaceutical and pharmacological properties. In this study, nutripriming with zinc sulfate (0.1%, 0.2%, and 0.3% solution) was applied to M. charantia seeds to optimize better dose. …”
Get full text

Millets as Future Grains: Need of Judicious Approach by Robin Badal, Arushi Saroch, Ankita Rai, Rohit Singh, Pramod Yadav, Shivakumar Harti, Pradeep Kumar Prajapati

“…To combat these problems, certain rules and regulations of Ayurvedic dietetics termed Ahara Vidhi Vidhan and processing methods such as germinating and dehulling should be followed.Conclusion:In a nutshell, millets have numerous nutritional and pharmacological properties but their impetuous use should be avoided. …”
Get full text

Carvacrol Essential Oil as a Neuroprotective Agent: A Review of the Study Designs and Recent Advances by Fahad Khan Tareen, Laura Catenacci, Sara Perteghella, Milena Sorrenti, Maria Cristina Bonferoni

“…This review not only focused on study designs and the pharmacological pathways taken by CV for neuroprotection but also focused on demographics, illustrating the trend of CV research studies in certain countries and the preferences for the use of in vitro or in vivo models in studies. …”
Get full text

Effect of Aquatic Exercises on Strength and Quality of Life in Sarcopenia Older Individuals by Aslı Nur Menteş, Büşra Çetin

“…Treatment options for sarcopenia include lifestyle changes, including physical activity and exercise training, medical nutrition therapy, and pharmacological therapy. Aquatic exercises are a type of exercise that involves the use of all the muscles of the body in a vertical position in the water, opposing the resistance of the water to its own body weight, while cardio and strength training are performed in parallel. …”
Get full text