Interrelation of Natural Polyphenol and Fibrosis in Diabetic Nephropathy by Ye Ma, Jiakun Wang, Juyue Fan, Huiyang Jia, Jinyao Li

“…In addition, potential targets and their inhibitors can be identified through these pathways, offering potential avenues of research for natural polyphenols in the pharmacological treatment of multisite fibrosis.…”
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3-Epi-betulinic acid 3-O-β-D-glucopyranoside (eBAG) induces autophagy by activation of AMP-activated protein kinase in hepatocellular carcinoma by Mengjie Liu, Xuqiang Liu, Kaiyue He, Yongping Jian, Yujia Li, Jinrong Guo, Jingyu Yang, Zhixiang Xu, Wenyi Kang

“…3-Epi-betulinic acid 3-O-β-D-glucopyranoside (eBAG) is a pentacyclic triterpene mainly distributed in food and medicinal plants, which exhibits various pharmacological properties. However, whether these functions are attributed to eBAG or additional components in these plants remain unknown. …”
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Advanced Copper Oxide Chemical and Green Synthesis: Characterization and Antibacterial Evaluation by Ecaterina Magdalena Modan, Adriana-Gabriela Schiopu, Sorin Georgian Moga, Denis Aurelian Negrea, Daniela Istrate, Ion Ciuca, Mihai Oproescu

“…Recent advancements in nanotechnology have improved the application of copper oxide (CuO) nanostructures, known for their diverse antibacterial, electrical, catalytic, optical, and pharmacological properties, which depend on nanoparticle morphology. …”
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Evaluating the in vitro activity of cefoperazone-sulbactam against Gram negative pathogens in blood stream infections using automated systems by Uksim Qadri, Sofiya Zaffar, Saleem Javaid Wani, Shugufta Roohi, Munazah Aman, Sabah Bhat, Umaya Majid

“…Nonetheless, regional data on the susceptibility patterns for this pharmacological combination remains scarce. The primary objective of this investigation was to assess the efficacy of the cefoperazone-sulbactam combination against prevalent Gram-negative bacteria isolated from blood cultures. …”
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Exploring Phytochemical Profile, Pharmaceutical Activities, and Medicinal and Nutritional Value of Wild Edible Plants in Ethiopia by Woinshet Kassie Alemu, Limenew Abate Worku, Rakesh Kumar Bachheti, Archana Bachheti, Adam Mekonnen Engida

“…This review focuses on using edible wild plants for pharmacological purposes, dietary supplements, and alternative medicine. …”
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PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis by Min Zhou, Yi Huang, Ping Xu, Shuyi Li, Chen Duan, Xiaoying Lin, Shilai Bao, Waiyi Zou, Jingxuan Pan, Chang Liu, Yanli Jin

“…PRMT1 regulates LSCs and leukemia development depending on its methyltransferase activity. Pharmacological inhibition of PRMT1 activity by MS023 remarkably eliminates LSCs and prolongs the survival of CML mice. …”
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Current evidence on the use of sugammadex for neuromuscular blockade antagonism during electroconvulsive therapy: a narrative review by Vivek Arora, Laurence Henson, Sandeep Kataria

“…In situations where Sch is contraindicated or otherwise problematic, rocuronium, followed by pharmacological antagonism with sugammadex, can provide a safe and effective muscle relaxation approach comparable to that of Sch in terms of duration of action. …”
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Genome-wide identification and expression analysis of bHLH gene family revealed their potential roles in abiotic stress response, anthocyanin biosynthesis and trichome formation in... by Guohua Ding, Yanping Shi, Kerui Xie, Hongbin Li, Guanghui Xiao

“…IntroductionLicorice stands out as an exceptional medicinal resource with a long history of application, attributed to its substantial pharmacological potential. The basic helix-loop-helix (bHLH) transcription factors (TFs) gene family, being the second-largest in plants, is vital for plant development and adapting to environmental shifts. …”
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Integrated bioinformatic approach of Balur therapy for breast cancer subtypes by Aristyani Sherry, Subagjo Saraswati, Rahayu Tintrim, Sumitro Sutiman B.

“…In conclusion, this study explained the pharmacological mechanisms of Balur therapy, which has great potential as a complementary therapy for breast cancer subtypes.…”
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Acupuncture as prophylaxis for chronic migraine: a protocol for a single-blinded, double-dummy randomised controlled trial by Claire Shuiqing Zhang, Bin Li, Lin Zeng, Lu Liu, Luo-peng Zhao, Kelun Wang, Jingxia Zhao, Linpeng Wang, Xianghong Jing

“…Acupuncture may serve as an alternative management for chronic migraine, where pharmacological prophylaxis is not suitable. However, the effects of acupuncture as migraine prophylaxis have not been confirmed. …”
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Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial by Mir Sadat-Ali, Abdallah S. AlOmran, Sulaiman A. AlMousa, Hasan N. AlSayed, Khalid W. AlTabash, Mohammed Q. Azam, Tarek M. Hegazi, Sadananda Acharya

“…The aim of this study was to compare the effect of autologous bone marrow-derived chondrocytes (ABMDCs) with pharmacological management of osteoarthritis of knee (OAK) and assess the benefit of the two in the improvement of pain relief, functional betterment, and quality of life (QOL). …”
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NURSING CARE FOR ACUTE PAIN IN POST-OPERATION FRACTURES by Ilkafah Ilkafah, Indah Dwi Lestari

“…Conclusion: The conclusion from the research conducted found that deep breathing relaxation technique is one of the effective non-pharmacological  pain management methods to reduce pain. …”
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Effect of Allium cepa L. on Lipopolysaccharide-Stimulated Osteoclast Precursor Cell Viability, Count, and Morphology Using 4′,6-Diamidino-2-phenylindole-Staining by Tatiane Oliveira, Camila A. Figueiredo, Carlos Brito, Alexander Stavroullakis, Anuradha Prakki, Eudes Da Silva Velozo, Getulio Nogueira-Filho

“…Allium cepa L. is known to possess numerous pharmacological properties. Our aim was to examine the in vitro effects of Allium cepa L. extract (AcE) on Porphyromonas gingivalis LPS and Escherichia coli LPS-stimulated osteoclast precursor cells to determine cell viability to other future cell-based assays. …”
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Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review by Roberto Gazzeri, Jacopo Mosca, Felice Occhigrossi, Marco Mercieri, Marcelo Galarza, Matteo Luigi Giuseppe Leoni

“…Refractory angina pectoris (RAP) is a clinical syndrome characterized by persistent chest pain caused by myocardial ischemia that is unresponsive to optimal pharmacological therapy and revascularization procedures. …”
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Amentoflavone from Selaginella bryopteris leaf extracts modulate MAPK signaling - Molecular modeling study for therapeutic target analysis by Praveen Mallari, Mashooq Ahmad Bhat

“…Subsequent research aims to characterize individual bioactive phytochemicals and their mode of action for possible pharmacological application.…”
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Comprehensive GC-MS Characterization and Histochemical Assessment of Various Parts of Three <i>Colchicum</i> Species from Bulgarian Flora by Ivayla Dincheva, Ilian Badjakov, Vasil Georgiev, Ivanka Semerdjieva, Radka Vrancheva, Ivan Ivanov, Atanas Pavlov

“…They underscore the ecological and pharmacological importance of endemic taxa and provide a framework for future research into their sustainable utilization and potential bioactivities.…”
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Single Standard Substance for the Simultaneous Determination of Eleven Components in the Extract of Paeoniae Radix Alba (Root of Paeonia lactiflora Pall.) by Menglan Shen, Qiaoyan Zhang, Luping Qin, Binjun Yan

“…., is widely used in many herbal medicine prescriptions/preparations. Since the pharmacological effects of PRA come from multiple chemical components, it is important to establish a method for the determination of those components in PRA extracts with simple operation and low cost, which is more suitable to evaluate the quality of PRA extracts and optimize the extraction process. …”
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The effect of self-compassion versus mindfulness interventions on autonomic responses to stress in generalized anxiety disorders by Xuejun Qi, Yonghui Shen, Xianwei Che, Ying Wang, Xi Luo, Lijun Sun

“…This study aimed to investigate the effects of a self-compassion intervention versus a mindfulness intervention on physiological arousal in response to induced stress.MethodsForty-seven patients with GAD had heart rate data collected during a stress task before and after a 2-week pharmacological treatment (known as treatment as usual, TAU), a self-compassion intervention + TAU or a mindfulness intervention + TAU. …”
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The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview by Ahmed Hussain, Hamid Tebyaniyan, Danial Khayatan

“…It is increasingly recognized that nuclear enzyme activities, such as histone deacetylases, can be used pharmacologically to induce stem cell differentiation and dedifferentiation. …”
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Brivaracetam to Treat Partial Onset Seizures in Adults by Dustin Latimer, David Le, Evan Falgoust, Patrick Ingraffia, Alaa Abd-Elsayed, Elyse M. Cornett, Rupin Singh, JooHee Choi, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“… # Conclusion The treatment of epilepsy with pharmacologic agents is a difficult task due to balancing the efficacy of the drug with the side effect profile that will allow for the best quality of life for the patient. …”
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