Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial by André Luiz Schuh Teixeira da Rosa, Marina Ribeiro Barreto da Costa, Gabriela Bezerra Sorato, Felipe de Moura Manjabosco, Érica Bonganhi de Bem, Lucas Dellazari, Arthur Bezerra Falcão, Lucas de Oliveira Cia, Olivia Sorato Bezerra, Rogério Boff Borges, Luis Augusto Rohde, Ana Soledade Graeff-Martins

“…Given this, exploring pharmacological alternatives for more effective management of DB associated with ASD is essential. …”
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Classifications for Proliferative Vitreoretinopathy (PVR): An Analysis of Their Use in Publications over the Last 15 Years by Salvatore Di Lauro, Mustafa R. Kadhim, David G. Charteris, J. Carlos Pastor

“…It was also noted whether classifications were used for comparison before and after pharmacological or surgical treatment. Results. 138 papers were included. 35 of them (25.4%) presented no classification reference or did not use any one. 103 publications (74.6%) used a standardized classification. …”
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NFAT5 Contributes to Osmolality-Induced MCP-1 Expression in Mesothelial Cells by Christoph Küper, Franz-X. Beck, Wolfgang Neuhofer

“…Hyperosmolality also induced activation of nuclear factor-κB (NF-κB). Accordingly, pharmacological inhibition of NF-κB significantly decreased osmolality-induced MCP-1 expression. …”
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Effect of turbinate reduction surgery on allergic rhinitis symptoms in hospitalized patients by Yusuf Kusuma Dewa, Andriana Tjitria Widi Wardani Sardjana, Moch. Agus Suprijono

“…Turbinate reduction surgery is a therapeutic option for allergic rhinitis refractory to pharmacological treatments. This study aimed to evaluate the effectiveness of turbinate reduction surgery in alleviating allergic rhinitis symptoms. …”
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Transcriptional role of androgen receptor in the expression of long non-coding RNA Sox2OT in neurogenesis. by Valentina Tosetti, Jenny Sassone, Anna L M Ferri, Michela Taiana, Gloria Bedini, Sara Nava, Greta Brenna, Chiara Di Resta, Davide Pareyson, Anna Maria Di Giulio, Stephana Carelli, Eugenio A Parati, Alfredo Gorio

“…Here, using Bicalutamide in order to pharmacologically inactivated AR, we investigated whether AR participates in the regulation of the transcription of the lncRNASox2OTat early embryonic stage. …”
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Hypothermia with Extreme Bradycardia following Spinal Cord Infarction of Septic Origin by Philippe Hantson, Thierry Duprez

“…Among other autonomic dysfunctions complicating acute spinal cord injury, deep hypothermia is rare but may induce serious cardiovascular complications. There are few pharmacological options to influence hypothermia. A 66-year-old woman was transferred to the intensive care unit (ICU) for serious cardiac arrhythmias (atrial fibrillation and asystole) in the context of a deep hypothermia (axillary temperature below 32°C). …”
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Comparative role of affective–Cognitive behavior therapy and jacobson's progressive muscular relaxation in managing pain among patients with fibromyalgia by M T Lakshmi Saranya, R Sreehari, C B Mithun, P I Sangeetha

“…Conclusion: Considering the effect of ACBT in reducing the Pain and FM Impact scores, ACBT shall be considered as an add-on psychological intervention along with the pharmacological management to yield better outcomes in FM patients. …”
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Uveitis associated with elevation of intraocular pressure – what is the optimal therapy? by Agnieszka Kubicka-Trząska

“…The aim of the article is to present the classification and contemporary knowledge about the pathophysiology and pharmacological management of uveitis associated with increased IOP.…”
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Mechanisms of Action of Mesenchymal Stem Cells in Metabolic-Associated Fatty Liver Disease by Sitong Yi, Qingwei Cong, Ying Zhu, Qiumin Xu

“…However, its pathophysiological mechanism is complicated, and currently, it has no FDA-approved pharmacological therapies. In recent years, mesenchymal stem cell (MSC) therapy has attracted increasing attention in the treatment of hepatic diseases. …”
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COMBINATION OF ADMINISTRATION OF PIPPER BETLE AND CURCUMA LONGA AGAINST ALBUS FLUOR IN ADOLESCENT GIRLS IN TAMBAK MAYOR NORTH SURABAYA CITY by Dewi Andriani, Rosari Oktaviana Mahundingan

“…Giving a decoction of Pipper Betle and Curcuma Longa is a non-pharmacological measure to treat Fluor Albus. This study aims to determine the effectiveness of giving a decoction of Pipper Betle and Curcuma Longa on the occurrence of vaginal discharge. …”
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Accessory Renal Artery Stenosis and Secondary Hypertension by Ariel A. Chung, Patricia R. Millner

“…Upon consultation with interventional radiology, pharmacologic treatment was recommended, and blood pressure control was ultimately achieved with a single agent. …”
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Simvastatin Does Not Affect Vitamin D Status, but Low Vitamin D Levels Are Associated with Dyslipidemia: Results from a Randomised, Controlled Trial by Lars Rejnmark, Peter Vestergaard, Lene Heickendorff, Leif Mosekilde

“…Our data do not support a pharmacological effect of statins on vitamin D status, but do suggest that vitamin D may influence plasma lipid profile and thus be of importance to cardiovascular health.…”
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Sustained Release of Prostaglandin E2 in Fibroblasts Expressing Ectopically Cyclooxygenase 2 Impairs P2Y-Dependent Ca2+-Mobilization by María Pimentel-Santillana, Paqui G. Través, Raquel Pérez-Sen, Esmerilda G. Delicado, Paloma Martín-Sanz, María Teresa Miras-Portugal, Lisardo Boscá

“…The inhibition of P2Y responses by PGE2 involves the activation of PKCs and PKD, a response that can be suppressed after pharmacological inhibition of these protein kinases. In addition to this, PGE2 reduces the fibroblast migration induced by P2Y-agonists such as UTP. …”
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IMPLEMENTATION OF BRAIN GYM THERAPY IN ELDERLY WITH DEMENTIA EXPERIENCING MEMORY IMPAIRMENT AT UPTD GRIYA WREDA JAMBANGAN SURABAYA: CASE STUDY by Rusdi Effendi

“…Conclusions: Brain gym therapy can be used as a non-pharmacological therapy to treat memory disorders in elderly people with dementia. …”
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Prolonged Helium Postconditioning Protocols during Early Reperfusion Do Not Induce Cardioprotection in the Rat Heart In Vivo: Role of Inflammatory Cytokines by Gezina Tanya Mei Ling Oei, Hamid Aslami, Raphaela Priscilla Kerindongo, Renske Johanna Steenstra, Charlotte Jacqueline Peter Beurskens, Anita Maria Tuip-de Boer, Nicole Petra Juffermans, Markus Werner Hollmann, Benedikt Preckel, Nina Claudia Weber

“…Postconditioning of myocardial tissue employs short cycles of ischemia or pharmacologic agents during early reperfusion. Effects of helium postconditioning protocols on infarct size and the ischemia/reperfusion-induced immune response were investigated by measurement of protein and mRNA levels of proinflammatory cytokines. …”
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The Pull-Through Technique for Recanalization of Transjugular Intrahepatic Portosystemic Shunt Dysfunction by Si-liang Chen, Cheng-jiang Xiao, Shuai Wang, Si-yi Jin, Jian-bo Zhao

“…Clinical success was defined as bleeding interruption and ascites regression without pharmacological support. All patients were followed up by clinical evaluation and Doppler ultrasound. …”
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Mydriasis Stability During Cataract Surgery in Patients with Systemic Comorbidities Using a Standardised Combination of Intracameral Mydriatics and Anaesthetic by Joanna Dereń-Szumełda, Mariola Dorecka, Mirosław Dereń, Ewa Mrukwa-Kominek

“…Stability was defined as a pupil diameter of ≥6.0 mm without additional pharmacological intervention and no significant change in its diameter (≥3.0 mm). …”
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Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence by Sashini D. Perera, Uthpala A. Jayawardena, Chanika D. Jayasinghe

“…Hence, well-controlled clinical trials and contemporary pharmacological approaches including activity guided fractionation and elucidation of the mode of action are encouraged to establish the use of E. hirta for dengue.…”
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Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization by Hui Zhang, Min Gao, Haiyan Wang, Junfeng Zhang, Lin Wang, Guanjun Dong, Qun Ma, Chunxia Li, Jun Dai, Zhihua Li, Fenglian Yan, Huabao Xiong

“…Atractylenolide I (ATR-I) is an active component of the Atractylodes macrocephala rhizome and possesses various pharmacological activities, including anti-tumor, anti-inflammatory, and anti-oxidant properties. …”
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Lack of Noradrenergic Modulation of Indirect Semantic Priming by Jacquelyne S. Cios, Regan F. Miller, Ashleigh Hillier, Madalina E. Tivarus, David Q. Beversdorf

“…In the context of this previous work, this suggests that more automatic processes such as priming and more controlled searches of the lexical and semantic networks such as problem solving may be mediated, at least in part, by distinct mechanisms with differing effects of pharmacological modulation.…”
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