Research progress of acupoint application therapy based on midnight-noon ebb-flow in the treatment of constipation after lumbar surgery (子午流注择时穴位贴敷改善腰椎术后便秘的研究进展)... by WANG Qiujie (王秋洁), WANG Yuanyuan (王媛媛), QING Jingwen (秦婧文), ZHANG Jianmeng (张建萌), GENG Qingwen (耿庆文)

“…Constipation can be effectively relieved by pharmacologic interventions. However, there are limitations such as drug dependence and adverse effects. …”
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The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Releva... by Kvido Smitka, Hana Papezova, Karel Vondra, Martin Hill, Vojtech Hainer, Jara Nedvidkova

“…The circulating autoantibodies can be purified and used as pharmacological tools in AN and BN. Further research is required to investigate the orexigenic/anorexigenic synthetic analogs and monoclonal antibodies for potential treatment of eating disorders in clinical practice.…”
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Type B non-Hodgkin lymphoma in a patient with acquired immunodeficiency virus with no detected viral load. Case report by Edwin Marcelo Miranda Solìs, Juan Fernando Orozco Herrera

“…For these reasons, we present the case of a 58-year-old patient, diagnosed with acquired immunodeficiency virus in the year 2000, who in the last ten years presented adequate clinical, virological, and pharmacological control. Suddenly and a few months ago, he began with symptoms related to a spinal cord compression syndrome at the lumbar level characterized by pain, functional impotence of the extremities and paresthesias. …”
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Effect of UV Irradiation on Interactions of α-Lipoic Acid with Free Radicals by Paweł Ramos, Piotr Pepliński, Barbara Pilawa

“…Application of electron paramagnetic resonance spectroscopy to characterize interactions of pharmacological substance with free radicals was confirmed.…”
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Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors by Gianluigi Zaza, Paola Tomei, Paolo Ria, Simona Granata, Luigino Boschiero, Antonio Lupo

“…Because of their specific pharmacological characteristics and their relative lack of nephrotoxicity, these inhibitors are valid option to calcineurine inhibitors (CNIs) for maintenance immunosuppression in renal transplant recipients with chronic allograft nephropathy. …”
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Effect of the Entorhinal Cortex on Ictal Discharges in Low-Mg2+-Induced Epileptic Hippocampal Slice Models by Ye-Jun Shi, Xin-Wei Gong, Hai-Qing Gong, Pei-Ji Liang, Pu-Ming Zhang, Qin-Chi Lu

“…The results showed that low-Mg2+ artificial cerebrospinal fluid induced interictal discharges in hippocampal slices, whereas, in combined EC-hippocampal slices the discharge pattern was alternated between interictal and ictal discharges, and ictal discharges initiated in the EC and propagated to the hippocampus. The pharmacological effect of the antiepileptic drug valproate (VPA) was tested. …”
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A Case Report of Mania and Psychosis Five Months after Traumatic Brain Injury Successfully Treated Using Olanzapine by Giordano F. Cittolin-Santos, Jesse C. Fredeen, Robert O. Cotes

“…There are few published pharmacologic trials for the treatment of acute mania following traumatic brain injury (TBI). …”
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Trauma-Induced Double-Seronegative Ocular Myasthenia Gravis: A Case Report by Mohammad Ali Khalid, Muhammad Jawad Awan, Ambreen Gull, Nida Hafeez, Bushra Ali, Fuad Ahmad Khan Niazi

“…History, examination and pharmacological (neostigmine test) tests were suggestive of ocular myasthenia gravis, however anti-acetylcholine receptor antibodies and anti-musk antibodies were negative. …”
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Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis by Michael P. Salna, Hannah M. Singer, Ali N. Dana

“…Moreover, elderly patients are prone to pharmacologic interactions due to multiple medications. …”
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GABAergic Neuronal Precursor Grafting: Implications in Brain Regeneration and Plasticity by Manuel Alvarez Dolado, Vania Broccoli

“…Numerous neurological disorders are caused by a dysfunction of the GABAergic system that impairs or either stimulates its inhibitory action over its neuronal targets. Pharmacological drugs have generally been proved very effective in restoring its normal function, but their lack of any sort of spatial or cell type specificity has created some limitations in their use. …”
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Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives by Bhagya Lakhmi Rajbongshi, Ashis K. Mukherjee

“…This review accentuates the need for rigorous scientific investigations, prior to clinical trials to validate their traditional uses, which would reveal the pharmacological interventions that will eventually advance human health and well-being.…”
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An AMBRA1, ULK1 and PP2A regulatory network regulates cytotoxic T cell differentiation via TFEB activation by Loredana Migliore, Valentina Cianfanelli, Fabrizia Zevolini, Monica Gesualdo, Leandro Marzuoli, Laura Patrussi, Cristina Ulivieri, Giuseppe Marotta, Francesco Cecconi, Francesca Finetti, Cosima T. Baldari

“…These effects were recapitulated by pharmacological inhibition of the AMBRA1 activator ULK1 or its interactor PP2A. …”
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Motor-Skill Learning Is Dependent on Astrocytic Activity by Ragunathan Padmashri, Anand Suresh, Michael D. Boska, Anna Dunaevsky

“…To test the hypothesis that astrocytic activity is necessary for motor-skill learning, we perturbed astrocytic function using pharmacological and genetic approaches. We find that perturbation of astrocytes either by selectively attenuating IP3R2 mediated astrocyte Ca2+ signaling or using an astrocyte specific metabolic inhibitor fluorocitrate (FC) results in impaired motor-skill learning of a forelimb reaching-task in mice. …”
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Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside by Sidra Tabassum, Silin Wu, Chang-Hun Lee, Bosco Seong Kyu Yang, Aaron M. Gusdon, Huimahn A. Choi, Xuefang S. Ren

“…We also evaluate various preclinical studies exploring pharmacological agents, gene therapy, and novel drug delivery systems designed to protect and restore mitochondrial function. …”
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THE EFFECT OF NONI (MORINDA CITRIFOLIA L.) LEAVES EXTRACT ON BRUISES HEALING AMONG PERSAUDARAAN SETIA HATI TERATE MARTIAL ARTS ATHLETES by Nur Hidayati, Muhammad Prasetiyo, Abdul Rokhman

“…Conclusions: Noni leaf ointment can significantly accelerate bruise healing without pharmacological therapy.…”
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Plant Sources, Extraction Methods, and Uses of Squalene by M. Azalia Lozano-Grande, Shela Gorinstein, Eduardo Espitia-Rangel, Gloria Dávila-Ortiz, Alma Leticia Martínez-Ayala

“…It is considered a molecule with pharmacological, cosmetic, and nutritional potential. …”
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Phoenix dactylifera L. (date palm) fruit extracts and fractions exhibit anti-proliferative activity against human pancreatic cancer cell lines by Reem A. Al Alawi, Jörg D. Hoheisel, Mohamed Saiel Saeed Alhamdani, Younis Baqi

“…The prepared date fruit extracts and fractions were pharmacologically evaluated on three pancreatic cancer cell lines: PT45P1, PANC-1, and SUIT-2. …”
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DENTAL ANXIETY – A PSYCHOSOCIAL CAUSE AFFECTING THE QUALITY OF LIFE – A SYSTEMATIC REVIEW by Andreea Sălcudean, Laria-Maria Trușculescu, Ramona Amina Popovici, Nicoleta Șerb, Ciprian Pașca, Cristina Raluca Bodo, Ramona Elena Crăciun, Iustin Olariu

“…Effective management strategies, including non-pharmacological approaches such as cognitive-behavioral therapy and relaxation techniques, have been shown to alleviate anxiety and improve patient outcomes. …”
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Standardized Application of Laxatives and Physical Measures in Neurosurgical Intensive Care Patients Improves Defecation Pattern but Is Not Associated with Lower Intracranial Press... by Martin Kieninger, Barbara Sinner, Bernhard Graf, Astrid Grassold, Sylvia Bele, Milena Seemann, Holger Künzig, Nina Zech

“…After the implementation of the SOP patients suffering from a neurosurgical disorder received pharmacological and nonpharmacological measures to improve bowel movements in a standardized manner within the first 5 days after admission to the intensive care unit (ICU) starting on day of admission. …”
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The Development and Application of Novel IR and NMR-Based Model for the Evaluation of Carminative Effect of Artemisia judaica L. Essential Oil by Muhammed Alzweiri, Ibrahim M. Alrawashdeh, Sanaa K. Bardaweel

“…Furthermore, owing to its sensitivity, our model provides a fundamental basis for the pharmacological assessment of trace amounts of oils with high precision and accuracy.…”
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