Quinazoline scaffold as a target for combating microbial resistance: Synthesis and antimicrobial profiling of quinazoline derivatives by Vishwanath Halappanavar, Sangappa Teli, Hanamant B. Sannakki, Dharyappa Teli

“…Quinazoline derivatives exhibit promising pharmacological effects and diverse chemical structures. …”
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Repetitive Transcranial Magnetic Stimulation, Cognition, and Multiple Sclerosis: An Overview by Grigorios Nasios, Lambros Messinis, Efthimios Dardiotis, Panagiotis Papathanasopoulos

“…Due to the lack of effective pharmacological treatments for cognition, cognitive rehabilitation and other nonpharmacological interventions such as repetitive transcranial magnetic stimulation (rTMS) have recently emerged and their potential role in functional connectivity is studied. …”
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Comparison between the chemical composition of essential oils isolated from biocultivated Salvia rosmarinus Spenn. (Rosmarinus officinalis L.) and some commercial products by Stanislava Ivanova, Vanya Nalbantova, Niko Benbassat, Velina Dzhoglova, Zoya Dzhakova, Nina Koleva, Veselin Vasilev, Daniela Grekova-Kafalova, Kalin Ivanov

“…(Rosmarinus officinalis L.) is an aromatic medicinal plant associated with rich phytochemical composition and significant pharmacological potential. The aim of the current study was to evaluate the chemical profile of eight samples containing essential oil (EO) from biocultivated Rosmarinus officinalis L. from different locations and various harvesting periods. …”
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Gene Array Studies in Renal Neoplasia by John P.T. Higgins

“…Yet renal cell carcinoma is often discovered at an advanced clinical stage and effective pharmacologic therapies for this disease remain to be discovered. …”
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Design, Synthesis, and Biological Evaluation of Novel Pyrrolo [2,3-b] Pyridine Derivatives for Nonalcoholic Fatty Liver Disease by Jialin Ma, Jing Li, Dongping Yao, Qi Wang, Xinzhou Chen, Feiyan Tao, Bin Chen, Yongmei Xie, Lang Bai, Yiwen Zhang

“…In this study, we successfully synthesized 18 novel SIS3 derivatives and evaluated them for pharmacological activity. F-9 and F-15 had potent weight-losing effects. …”
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Low-Dose Fluoxetine in Four Children with Autistic Spectrum Disorder Improves Self-Injurious Behavior, ADHD-Like Symptoms, and Irritability by Juan Pablo Lucchelli, Gilles Bertschy

“…In these situations, pharmacological treatments are sometimes used. Selective Serotonin Reuptake Inhibitors- (SSRI-) based treatments have been the subject of several publications: case reports and controlled studies, both of which demonstrate efficacy on the symptoms mentioned above, even if no consensus has been reached concerning their usage. …”
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Antioxidant Effects of E. alba: A Narrative Review by Keyur Dudhat, Anita Wanjari, Yogi Tajane, Shubham Khanke

“…Overall, E. alba antioxidant potential makes it a promising candidate for further exploration in the development of pharmacologically active natural products with antioxidant properties.…”
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Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis by David Qixiang Chen, José Adalberto Inzunza Domínguez, Juan Manuel Valle Uzeta, Abhiram P. Pushparaj, Abhiram P. Pushparaj, Jonathan E. Dickinson

“…Ibogaine, a psychoactive alkaloid, has been proposed as a potential neuroregenerative agent due to its multifaceted pharmacological profile. We present two case studies of MS patients who underwent a novel ibogaine treatment, highlighting significant neuroimaging changes and clinical improvements. …”
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Bilateral Facial Palsy in Rapidly Progressive Course of Wegener’s Granulomatosis: A Case Report by Anna Roszkowska, Monika Morawska-Kochman, Hanna Temporale, Małgorzata Sikorska-Żuk, Tomasz Kręcicki

“…In the presented case, considering the clinical course, it was necessary to apply both pharmacological and surgical treatments.…”
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Reimagining Venom Harvesting: Practical Electrostimulation on <i>Vespa velutina</i> Nest in Nature by Xesús Feás, Daniel J. Cabadas, Carmen Vidal

“…The growing interest in <i>Vespa velutina</i> venom stems primarily from its impact on human health due to stings and its potential pharmacological applications. Traditionally, venom extraction methods have relied on capturing individual hornets or removing and euthanizing entire nests, followed by dissection of venom sacs—a labor-intensive and disruptive process. …”
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IDH Mutant Cholangiocarcinoma: Pathogenesis, Management, and Future Therapies by Alexander Bray, Vaibhav Sahai

“…These neomorphic point mutations endow mutant IDH (mIDH) with the ability to generate an R-enantiomer of 2-hydroxyglutarate (R2HG), a metabolite that drives malignant transformation through aberrant epigenetic signaling. As a result, pharmacologic inhibition of mIDH has become an attractive therapeutic strategy in CCAs harboring this mutation. …”
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Neuroprotective strategies in acute ischemic stroke: A narrative review of recent advances and clinical outcomes by Min Zhao, Yue Qiao, Alexander Weiss, Wenbo Zhao

“…Recent advancements in neuroprotective approaches, including pharmacologic agents such as nerinetide edaravone, and uric acid, as well as nonpharmacological interventions, such as remote ischemic conditioning and normobaric hyperoxia, offer promising potentials in stroke care. …”
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Nursing of a patient with acne treated by Chinese herbal medicine mask (中药面膜治疗痤疮1例的护理体会) by GENG Miaomiao (耿苗苗), SUN Mingli (孙明丽), TANG Ling (唐玲), XU Jingjin (徐京巾), GUO Xinyi (郭新一)

“…Under the guidance of Traditional Chinese Medicine syndrome differentiation and pharmacological characteristics of the Chinese herbal mask, targeted nursing interventions were carried out to relieve the facial acne and negative emotion of the patient. …”
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Novel Interventional Approaches for ALI/ARDS: Cell-Based Gene Therapy by Ying-Gang Zhu, Jie-Ming Qu, Jing Zhang, Hong-Ni Jiang, Jin-Fu Xu

“…The present therapeutic strategies for ALI/ARDS including supportive care, pharmacological treatments, and ventilator support are still controversial. …”
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ER Dysfunction and Protein Folding Stress in ALS by Soledad Matus, Vicente Valenzuela, Danilo B. Medinas, Claudio Hetz

“…Recent studies using pharmacological and genetic manipulation of the unfolded protein response (UPR), an adaptive reaction against ER stress, have demonstrated a complex involvement of the pathway in experimental models of ALS. …”
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Prevention and Management of Gastroesophageal Varices in Cirrhosis by Yen-I Chen, Peter Ghali

“…We will discuss indications for primary prophylaxis and the different modes of therapy, pharmacological and interventional treatment in acute bleeding, and therapeutic options in preventing recurrent bleeding. …”
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Recent Advances in Natural Products Derived from Marine Echinoderms and Endophytic Microbes: Chemical Insights and Therapeutic Potential by Shuangyu Li, Yan Xiao, Qiang Li, Mingzhi Su, Yuewei Guo, Xin Jin

“…In the past five years, remarkable progress has been made in the isolation, structural elucidation, and pharmacological assessment of these bioactive compounds. …”
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Nonalcoholic Fatty Liver Disease: A Clinical Approach and Review by Maitreyi Raman, Johane Allard

“…Currently, there are no pharmacological agents recommended in the treatment of NAFLD, although preliminary studies suggest promising agents in the future.…”
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Chronic Disease Management in Patients with Non-infectious Arthritis: Challenges and Solutions by WENG Xisheng, ZHANG Fengchun

“…To address these challenges, a systematic strategy for chronic disease management of NIS needs to be developed at the national level, which encompasses increasing popularization of science, improving the referral system, using artificial intelligence (AI) technology to assist in early diagnosis, and implementing interventions including optimized pharmacological/surgical treatments and multidisciplinary collaboration. …”
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DRUG-INDUCED GINGIVAL OVERGROWTHS: AN INSIGHT INTO MOLECULAR MECHANISMS by Gabriel Rotundu, Diana Tatarciuc, Bogdan Amărioarei, Dana Budală, Ruxandra Stan, Oana Butnaru, Alexandra Mârțu, Liliana Păsărin, Ionut Luchian

“…Drug-induced gingival overgrowths (DIGO) represent a significant side effect of various pharmacological treatments, particularly anticonvulsants, immunosuppressants, and calcium channel blockers. …”
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