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4121
Multidisciplinary, multicenter consensus for the care of patients affected with Sturge–Weber syndrome
Published 2025-01-01“…Results Through a Delphi consensus methodology, 28 recommendations have been developed concerning (i) dermatological SWS manifestations and related treatment timing and modalities, (ii) neurological referral, diagnosis, pharmacological treatment of neurological signs and symptoms, neurosurgical indications, neurocognitive evaluation and related treatment, psychosocial support and patient follow-up, (iii) diagnosis of ophthalmological manifestations, medical and surgical treatment, and follow-up, (iv) maxillofacial surgical treatment, (v) oral cavity assessment, care and follow-up, and (vi) primary care paediatrician/general practitioner involvement. …”
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4122
Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution?
Published 2023“…Limited pharmacological studies have been conducted on plant species used against poultry helminths. …”
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4123
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4124
Treatment Patterns for Patients on Overactive Bladder Therapy: A Retrospective Statistical Analysis Using Canadian Claims Data
Published 2016-10-01“…Treatment switching may be considered in order to maximise benefits from pharmacological therapy, but there are relatively few data on OAB therapy switching to second and third-lines of medication. …”
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4125
Combination of functional dyspepsia syndrome and irritable bowel syndrome
Published 2011-06-01“…However, the overall prognosis for this patient is unfavorable. Prescription of pharmacological agents can hardly result in complete cure, as presence of almost constant complaints has «secondary psychologic benefit» for this patient.Conclusion. …”
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4126
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4127
Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer
Published 2025-02-01“…Consequently, these treatments decrease PDAC cell proliferation and motility in vitro. From a pharmacological perspective, different statins produce anti-neoplastic effects in synergy with scDb-hERG1-β1. …”
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4128
Inflammatory adhesion mediates myocardial segmental necroptosis induced by mixed lineage kinase domain-like protein in acute myocardial infarction
Published 2025-01-01“…In a mouse model of AMI, we observed MSN, which was absent in immunosuppressed mice. Pharmacological depletion of macrophages or genetic knockout of macrophage-specific MLKL (MLKLM−KO) reduced the occurrence of MSN. …”
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4129
Harm reduction strategies in acute care for people who use alcohol and/or drugs: A scoping review.
Published 2023-01-01“…A variety of intervention modalities including pharmacological, decision support, safer consumption, early overdose detection and turning a blind eye were identified. …”
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4130
Complete mitogenome characteristics and phylogenetic analysis of traditional Chinese medicinal plant Tinospora sagittata (Oliv.) Gagnep. from the Menispermaceae family
Published 2025-02-01“…Its tuberous roots have been used as traditional Chinese medicine (TCM) for pharmacological properties and are commonly known name as “Jin Guo Lan”. …”
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4131
Comparative Evaluation of Cyclooxygenase Inhibition Profiles Across Various NSAID Forms and Doses: Implications for Efficacy and Adverse Effects
Published 2024-12-01“…Abstract Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain disorders and exert pharmacological effects by inhibiting cyclooxygenase (COX). …”
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4132
Ultrasound renal denervation in hypertensive patients: A systematic review and meta-analysis.
Published 2025-01-01“…Ultrasound-based renal denervation (uRDN) has emerged as a promising non-pharmacological approach. This study aims to investigate the safety and efficacy of uRDN in hypertensive patients.…”
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4133
Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i>
Published 2025-01-01“…These compounds have various pharmacological functions, including anti-tumor, antioxidant, anti-inflammatory, liver-protective, and immune-regulating effects. …”
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4134
Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve
Published 2025-01-01“…Our study supports EA could be used as a potential non-pharmacological therapy for PIPN.…”
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4135
Features of the Parameters of 24-Hours pH-Impedance and High-Resolution Esophageal Manometry in Patients with Barrett's Esophagus on Proton Pump Inhibitors
Published 2023-06-01“…Predictors of insufficiently successful treatment of patients with Barrett's esophagus may be both insufficient pharmacological effect of proton pump inhibitors themselves, and motility disorders that cause the presence of non-acid reflux, decreased esophageal clearance, which in turn may cause the patient's symptoms to persist and adversely affect the condition of the esophageal mucosa.…”
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4136
Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
Published 2022-01-01“…Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects. …”
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4137
The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases
Published 2024-01-01“…Given the increasing pace of pharmacologic innovation, timely updates of clinical practice guidelines are critical to evolving the standard of care and practicing evidence-based medicine.…”
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4138
Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal
Published 2025-02-01“…Abstract Glucose transporter type 1 deficiency syndrome (GLUT1DS) commonly presents with early‐onset epilepsy that often resists conventional pharmacological treatment. Ketogenic diet therapy (KDT) is the preferred approach to address the underlying metabolic anomaly. …”
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4139
Effects of entinostat, quisinostat, and tubastatin-A on alcohol consumption in male high ethanol consuming rats
Published 2025-02-01“…BackgroundThe interaction between genetics, epigenetics, and the environment plays a key role in the development of alcohol use disorder (AUD). Pharmacological treatments targeting histone deacetylases (HDACs) suggest that HDAC inhibitors (HDACi) may be potential pharmacotherapeutic treatments for AUD. …”
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4140
Mechanistic study on the mitigation of cadmium accumulation in Ligusticum sinense cv. Chuanxiong through plant growth-promoting rhizobacteria Arthrobacter sp. CX-2
Published 2025-03-01“…Above all, as a TCM, the pharmacological effects of L. Chuanxiong were not affected by the addition of CX-2, which was confirmed through cell experiments. …”
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