Cytokine-Leukotriene Receptor Interactions by Marek Rola-Pleszczynski, Jana Stankova

“…Biochemical and pharmacological studies have identified the structure of leukotrienes, the pathways that lead to their synthesis, and the signaling events they trigger when they interact with their cognate receptors. …”
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Progress on neuromodulation for treatment of central pain by GAN Yu, WAN Jun⁃ge, LI Zhong⁃hua, LI Shuai, HAN Shuai

“…Central pain often arises as a sequela of lesions in the central somatosensory nervous system, and the intensity of pain is generally severe, significantly impacting patients' quality of life. Conventional pharmacological therapies usually have limited efficacy. …”
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Resveratrol as a potential broad-spectrum compound for cancer treatment by Li Kar Stella Tan, Chee Wun How, Jhi Biau Foo, Kooi Yeong Khaw, Bey Hing Goh, Yong Sze Ong

“…Resveratrol (RSV), the stilbenes found in red wine, is one of the phytochemicals that exhibits various pharmacological therapeutic effects including cancer. …”
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Anesthetic Related Advances with Cyclodextrins by Mark Welliver, John P. McDonough

“…This unique ability to encapsulate lipophilic molecules and maintain water solubility confers numerous pharmacologic advantages for both drug delivery and removal. …”
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Buprenorphine for Chronic Pain: A Safer Alternative to Traditional Opioids by Suhani Dalal, Ahish Chitneni, Amnon A. Berger, Vwaire Orhurhu, Bilal Dar, Bennett Kramer, Anvinh Nguyen, John Pruit, Charles Halsted, Alan D. Kaye, Jamal Hasoon

“…Buprenorphine offers a safer alternative for patients who require opioids to manage chronic pain, given the unique pharmacological properties that allow it to provide adequate analgesia with less abuse potential.…”
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Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review by Ayodele Atolagbe, Stanley Nkemjika, Olusegun Popoola, Oluwatoyin Oladeji, Irina Kogan, Haroon Saeed, Tolulope Olupona

“…Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. …”
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Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications by Marta Szekalska, Agata Puciłowska, Emilia Szymańska, Patrycja Ciosek, Katarzyna Winnicka

“…The focus of the paper is to describe biological and pharmacological activity of alginates and to discuss the present use and future possibilities of alginates as a tool in drug formulation. …”
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Guidelines for the management of patients with Crohn’s disease. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology by Michał Łodyga, Piotr Eder, Magdalena Gawron-Kiszka, Agnieszka Dobrowolska, Maciej Gonciarz, Marek Hartleb, Maria Kłopocka, Ewa Małecka-Wojciesko, Piotr Radwan, Jarosław Reguła, Edyta Zagórowicz, Grażyna Rydzewska

“…It contains 46 recommendations for the diagnosis and treatment, both pharmacological and surgical, of Crohn's disease in adults. …”
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PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW by Rabia Noor

“…Majority of the drugs possesses low solubility leading to poor absorption and erratic bioavailability and thus failed to achieve a desired pharmacological response. Therefore formulation scientists have adopted various techniques to overcome solubility and bioavailability issues following oral administration. …”
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Synthesis of 1H-pyrazolo[3,4-b]pyridine analogues by Yen Nguyen, Greg Petruncio, Schroeder M. Noble, Mikell Paige

“…Many compounds containing the pyrazolo[3,4-b]pyridine scaffold have been found to have various pharmacological activities such as anticancer, anti-inflammatory, anti-bacterial, antihyperglycemic, and anxiolytic properties. …”
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LITERATURE REVIEW ON GLUCOSAMINE AND CHONDROITIN IN OSTEOARTHRITIS TREATMENT by Dang Thi Soa*, Vu Thi Thuy, Nguyen Duc Trung, Bien Thi Thuc Uyen, Le Thi Hai Yen, Tran Trung Hieu, Tran Thao Linh

“…Recently, slow-acting anti- osteoarthritis drugs, including glucosamine, chondroitin sulfate, and diacerein, have been suggested as key pharmacological options for treating this condition. However, Vietnamese-language resources on these active ingredients remain limited. …”
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Resistant Hypertension and Obstructive Sleep Apnea: The Sparring Partners by Costas Thomopoulos, Helena Michalopoulou, Alexandros Kasiakogias, Anna Kefala, Thomas Makris

“…Effective CPAP therapy qualifies as an effective “add-on” to the underlying antihypertensive pharmacological therapy, and emerging evidence underlines the favorable effect of mineralocorticoid antagonists on both resistant hypertension and obstructive sleep apnea treatment.…”
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Resolution of Osseous Sarcoidosis with Methotrexate by Christopher Kanner, Bonita Libman, Morgan Merchand, Diego Lemos

“…We present a case of widespread skeletal involvement of sarcoidosis without evidence of concurrent pulmonary disease demonstrating marked clinical improvement and near-complete resolution of imaging abnormalities on magnetic resonance imaging (MRI) following the use of methotrexate as the primary pharmacologic agent.…”
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Dynamic renoscintigraphy in cardiology and cardiac surgery by V.Yu. Kundin, I.V. Noverko, A.G. Mazur

“…The article presents the pharmacological test with captopril used for evaluation of renal function in hypertension, features of such test in cardiology practice and its evaluation in different clinical situations. …”
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Traditional Uses, Chemical Constituents, and Biological Activities of Bixa orellana L.: A Review by Daniela de Araújo Vilar, Marina Suênia de Araujo Vilar, Túlio Flávio Accioly de Lima e Moura, Fernanda Nervo Raffin, Márcia Rosa de Oliveira, Camilo Flamarion de Oliveira Franco, Petrônio Filgueiras de Athayde-Filho, Margareth de Fátima Formiga Melo Diniz, José Maria Barbosa-Filho

“…This study shows the well-characterized pharmacological actions that may be considered relevant for the future development of an innovative therapeutic agent.…”
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A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology by Ge Wang, Xiaoyan Peng

“…On the other hand, although MTX has an excellent pharmacological efficacy, MTX associated side effects in clinical use, which vary from patient to patient, are nonnegligible. …”
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Spinal Cord Injury Research in Mice: 2008 Review by Inge Steuer, Pierre A. Guertin

“…A variety of approaches, including advanced genetics and molecular techniques, have allowed a number of key findings in the field of secondary degeneration, repair, regeneration (including insights from peripheral nerve lesion models), metabolic dysfunctions, and pharmacological neuromodulation.…”
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A Review of Current Management of Vitreomacular Traction and Macular Hole by Alfredo García-Layana, José García-Arumí, José M. Ruiz-Moreno, Lluís Arias-Barquet, Francisco Cabrera-López, Marta S. Figueroa

“…A treatment algorithm to be used in clinical practice in patients with VMA, VMT, and MH based on the presence of symptoms, visual acuity, associated epiretinal membrane, and width of the vitreous attachment is presented. Observation, pharmacologic vitreolysis with ocriplasmin, and surgical treatment are positioned as treatment options in the different steps of the therapeutic algorithm, with clear indications of the paths to be followed according to the initial presenting manifestations and the patient’s clinical course.…”
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Benefits that Asthmatic Patients Receive after the Application of a Physiotherapeutic and Rehabilitative Treatment by Ismaray Sacerio González, Vivian Isabel Chávez Pérez, Belkis González Aguiar

“…Its prevalence continues to increase despite the fact that effective therapeutic manuals are currently available for the correct management of the main symptoms of the disease. The non-pharmacological treatment of this condition is based on three pillars: education about the disease, guides for professionals and patients, and respiratory physiotherapy. …”
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Role of Neutrophil Apoptosis in the Resolution of Inflammation by Driss El Kebir, János G. Filep

“…This review will focus on outside-in signals that provide survival cues for neutrophils, the hierarchy of pro- and antiapoptotic signals, and molecular targets in the antiapoptotic signaling network that can be exploited by endogenously produced bioactive lipids, such as lipoxins or pharmacological inhibitors, including cyclin-dependent kinase inhibitors, to redirect neutrophils to apoptosis in vivo, thus promoting resolution of inflammation.…”
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