Pathophysiology of Portal Hypertension and Esophageal Varices by Hitoshi Maruyama, Osamu Yokosuka

“…The major therapeutic strategy of esophageal varices consists of primary prevention, treatment for bleeding varices, and secondary prevention, which are provided by pharmacological, endoscopic, interventional and surgical treatments. …”
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Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response by Lila Aboueid, Richard H. McCarthy

“…The combination is thought to mimic the pharmacological profile of clozapine, rendering it as a possible alternative to traditional clozapine treatment.…”
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Current and Novel Therapies for Cluster Headache: A Narrative Review by Bruna de Freitas Dias, Christopher L. Robinson, Maria Dolores Villar-Martinez, Sait Ashina, Peter J. Goadsby

“…Future research continues to explore novel pharmacological targets, interventional procedures, and the potential role of psychedelics in CH management. …”
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The antioxidant potential of bacoside and its derivatives in Alzheimer's disease: The molecular mechanistic paths and therapeutic prospects by Dipanjan Karati, Swarupananda Mukherjee, Souvik Roy

“…Bacoside A, Baccoside B, Apigenin, Betullinic acid, etc. are the pharmacologically active congeners of Brahmi belonging to several chemical families. …”
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Probiotics in irritable bowel syndrome – is the quest for the right strain over? Rapid review of existing guidelines and recommendations by Wojciech Marlicz, Karolina Skonieczna-Żydecka, Patrycja Krynicka, Igor Łoniewski, Grażyna Rydzewska

“…The management of IBS consists of pharmacological and non-pharmacological treatments; however, the data of their long-term efficacy are scarce. …”
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NMDA Reduces Tau Phosphorylation in Rat Hippocampal Slices by Targeting NR2A Receptors, GSK3β, and PKC Activities by Audrée De Montigny, Ismaël Elhiri, Julie Allyson, Michel Cyr, Guy Massicotte

“…In the present study, pharmacological inhibitors were deployed to investigate potential processes by which the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors modulates Tau phosphorylation in rat hippocampal slices. …”
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The effectiveness of dance interventions on the cognitive functioning of people with dementia or cognitive impairment: A systematic review by Dauda Salihu, Surajo Kamilu Sulaiman, Umar Muhammad Bello, Osama Mohamed Elsayed Ramadan, Hadiza Yahaya, Muhammad Chutiyami

“…In the search for non-pharmacological interventions, dance has emerged as a potential complementary therapy to support people with dementia or cognitive impairment. …”
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Psychological interventions for patients with delirium in intensive care: A scoping review protocol. by Madiha Shaikh, Dorothy M Wade, Lara King, Liam Mackay, Isabelle Symes, Anam Syeda, Anna Greenburgh

“…However, current non-pharmacological interventions often fail to consider this issue. …”
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THE EFFECTIVENESS OF THE DECOCTION OF RED BETEL LEAVES (PIPER CROCANTUM) AGAINST THE REDUCED SYMPTOMS OF FLUOR ALBUS IN ADOLESCENT GIRLS by Rosa Purwanti, Rini Hayu Lestari, Niken Grah Prihartanti

“…To reduce the symptoms of fluor albus, non-pharmacological treatment from the decoction water of red betel leaves (Piper crocantum) was used in the present study. …”
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Evaluating comparative effectiveness of psychosocial interventions for persons receiving opioid agonist therapy for opioid use disorder: protocol for a systematic review by Brian Hutton, Beverley Shea, Kimberly Corace, David Moher, Danielle B Rice, Becky Skidmore, Kednapa Thavorn, Sheena Taha, Dianna Wolfe, Fatemeh Yazdi, Beth A Sproule, Melanie Willows, Patricia Poulin, Gary Garber, Amy Porath, Leila Esmaeilisaraji

“…Current clinical guidelines recommend that individuals with persons with opioid use disorder (OUD) receive pharmacological (eg, opioid agonist therapy) and psychosocial (eg, cognitive behavioural therapy) therapy; however, the best combination of pharmacologic and psychosocial components is not known. …”
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Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy by Axel H. Schönthal

“…Other studies seek to pharmacologically aggravate chronic ER stress in cancer cells in order to enhance apoptosis and achieve tumor cell death. …”
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Shadow puppetry therapy enhances dementia-related cognitive function and interpersonal relationship by Shu-Yuan Chao, Hsiao-Mei Chen, Bei-Yi Su

“…Background: With the growing demand for dementia care, non-pharmacological interventions, such as creative arts therapies, have been proven effective in stabilizing cognitive function. …”
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Evaluating a multicomponent intervention for managing kidney outcomes among patients with moderate or advanced chronic kidney disease (CKD): protocol for the Strategies for Kidney... by Tazeen Hasan Jafar, Ngiap Chuan Tan, Mihir Gandhi, Sungwon Yoon, Eric Finkelstein, Peter Moey Kirm Seng, Ruiheng Ong, Anandan Gerard Thiagarajah, Bing Long Lee, Ka Chi To, Aminath Shiwaza Moosa

“…Effective CKD management requires comprehensive care packages that integrate both pharmacological and non-pharmacological interventions within collaborative, team-based models, aiming to enhance patient outcomes and overall quality of life. …”
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Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: a systematic guideline review by Maren Bredehorst, Ana I. González-González, Lara Schürmann, Dennis Firmansyah, Christiane Muth, Jörg Haasenritter, Veronika van der Wardt, Svetlana Puzhko

“…Recommendations, with their strength and evidence level, were thematically coded and clustered around clinical questions using ATLAS.ti.ResultsWe included 26 CPGs from which we extracted 581 recommendations on risk assessment, non-pharmacological, and pharmacological interventions. Twenty-one guidelines (81%) were rated as having “very good” methodological quality. …”
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Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial by Yaadwinder Shergill, Danielle B. Rice, Eve-Ling Khoo, Virginia Jarvis, Tinghua Zhang, Monica Taljaard, Keith G. Wilson, Heather Romanow, Brittany Glynn, Rebecca Small, Joshua A. Rash, Andra Smith, Lynette Monteiro, Catherine Smyth, Patricia A. Poulin

“…Addressing pain with psychosocial interventions as an adjunct to pharmacological treatment is often recommended for CNP. …”
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Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion by Katsuya Sakimura, Tatsuya Maekawa, Shin-ichi Kume, Takeshi Ohta

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The Dissemination of Rift Valley Fever Virus to the Eye and Sensory Neurons of Zebrafish Larvae Is Stat1-Dependent by Sebastiaan ter Horst, Aleksandra Siekierska, Ann-Sofie De Meulemeester, Arno Cuvry, Laura Cools, Johan Neyts, Peter de Witte, Joana Rocha-Pereira

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Guidelines for the management of ulcerative colitis. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology by Piotr Eder, Michał Łodyga, Magdalena Gawron-Kiszka, Agnieszka Dobrowolska, Maciej Gonciarz, Marek Hartleb, Maria Kłopocka, Ewa Małecka-Wojciesko, Piotr Radwan, Jarosław Reguła, Edyta Zagórowicz, Tomasz Banasiewicz, Marek Durlik, Grażyna Rydzewska

“…It contains 49 recommendations for the diagnosis and treatment, both pharmacological and surgical, of ulcerative colitis in adults. …”
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Pharmacokinetic Interactions between Cardiovascular Medicines and Plant Products by Irina-Iuliana Costache, Anca Miron, Monica Hăncianu, Viviana Aursulesei, Alexandru Dan Costache, Ana Clara Aprotosoaie

“…Plant products can influence pharmacokinetics or/and pharmacological activity of coadministered drugs and some of these interactions may lead to unexpected clinical outcomes. …”
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INTEGRATING HYPERTONIA REHABILITATION, INTRAORAL REHABILITATION, AND ANXIETY MANAGEMENT FOR COMPREHENSIVE PATIENT CARE- PART1 by Lucian Stefan Burlea, Doriana Agop Forna, Mihaela Salceanu, Violina Budu, Vlad Proca, Bogdan Petru Bulancea, Tudor Hamburda, Maria Antonela Beldiman

“…As premedication, miorelaxants, adjuvants for inflammatory processes (which result in antalgic hypertonic phenomena), and during local anesthesia through neuromuscular transmission blockage, miorelaxants are a class of pharmacological agents with various structures and mechanisms of action that are highly helpful in treating stomatognatic dysfunctions. …”
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