Effect of life skills training by a midwife on pregnancy anxiety: A randomized controlled trial by Fatemeh Hassanpour, Mozhgan Javadnoori, Elham Maraghi, Fariba Zargar Shirazi

“…Therefore, it can be used by midwives as an effective non-pharmacologic approach in pregnancy .…”
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Description of network meta-analysis geometry: A metrics design study. by Fernanda S Tonin, Helena H Borba, Antonio M Mendes, Astrid Wiens, Fernando Fernandez-Llimos, Roberto Pontarolo

“…<h4>Methods</h4>A previous systematic review of NMAs of pharmacological interventions was performed. Data on the graph's presentation were collected. …”
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In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial. by Baback Roshanravan, Sophia Z Liu, Amir S Ali, Eric G Shankland, Chessa Goss, John K Amory, H Thomas Robertson, David J Marcinek, Kevin E Conley

“…This response represents the first demonstration of a pharmacological intervention that can reverse mitochondrial dysfunction in vivo immediately after treatment in aging human muscle.…”
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Intervention Programmes for First-Episode Psychosis: A Scoping Review by Marta Gouveia, Tânia Morgado, Tiago Costa, Francisco Sampaio, Amorim Rosa, Carlos Sequeira

“…The results showed that there is a great deal of variety in the characteristics of the programmes, with interventions ranging from single-component strategies, such as cognitive–behavioural therapy (CBT) and cognitive remediation therapy (CRT), to multicomponent programmes that integrate a number of different approaches, including psychosocial, pharmacological, and family-focused strategies. The objectives included attempts to improve cognitive functioning; enhance coping skills; reduce caregiver burden; and address symptoms such as anxiety, depression, and hallucinations. …”
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Resource constraints, patient emotions, and therapy: experiences of healthcare providers in the screening and management of gestational diabetes mellitus in northern Ghana by Mohammed Bukari, Abdulai Abubakari, Hawa Malechi, Thomas Hinneh, Humphrey Garti, Faith Agbozo

“…The second theme was care-centred experiences, which explored patient emotions during GDM care, and the care they receive post-GDM diagnosis, with subthemes namely: raw emotions, non-pharmacological therapy, and pharmacotherapy. Conclusion Findings suggest the need for health system strengthening through the training and recruitment of dedicated skilled personnel, as well as government intervention through policy revision to cover the cost of GDM diagnostic tests. …”
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Gaps in the Management of Hypertensive Patients in a Metropolitan Area of Havana by Armando Rodríguez Salvá, Alejandra Caridad Piña Alonso, Addys Díaz Piñera, René García Roche, Susana Balcindes Acosta

“…<strong><br />Results:</strong> a 92.3 % of the interviewees said they felt the need for care in the last year, of these, 80.7 % had access to health services. 98.1 % had indicated pharmacological treatment, with diuretics being the most used with 61 %. 50.7 % have adherence to treatment according to the Morisky test. 24.2 % were not seen by their doctor in the last year, the main reason was the no programming or appointment to consultation. 56.6 % had their blood pressure figures controlled. …”
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Spectroscopic, DFT, anti-bacterial, and in-silico investigations of novel semicarbazone and thiosemicarbazone synthesised from asymmetrical chalcones by Nikita Sharma, Har Lal Singh

“…Later, computational tools were utilised for evaluating pharmacological attributes such as bioavailability score, Lipinski rule, absorption, distribution, metabolism, excretion and toxicity. …”
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A Clinically-Reasoned Approach to Manual Therapy in Sports Physical Therapy by Steven Short, Matthew Tuttle, Dillon Youngman

“…Given the risks associated with pharmacological pain management, the cost of passive modalities like biophysical agents (electrical stimulation, photobiomodulation, ultrasound, etc), and the indications from the evidence-base when combined with active therapies, manual therapy can be a safe and effective treatment strategy to keep athletes active…”
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Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…Weight reduction is recommended. In addition, pharmacological treatment must be performed. All individuals have statins implemented. …”
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Fully Automated Production of (((<i>S</i>)-1-Carboxy-5-(6-([¹⁸F]fluoro)-2-methoxynicotinamido)pentyl)carbamoyl)-<span style="font-variant: small-caps">l</span>-glutamic... by Philipp Krapf, Thomas Wicher, Boris D. Zlatopolskiy, Johannes Ermert, Bernd Neumaier

“…<b>Background:</b> The radiotracer [¹⁸F]JK-PSMA-7, a prostate cancer imaging agent for positron emission tomography (PET), was previously synthesized by indirect radiofluorination using an ¹⁸F-labeled active ester as a prosthetic group, which had to be isolated and purified before it could be linked to the pharmacologically active Lys-urea-Glu motif. Although this procedure could be automated on two-reactor modules like the GE TRACERLab FX2N (FXN) to afford the tracer in modest radiochemical yields (RCY) of 18–25%, it is unsuitable for cassette-based systems with a single reactor. …”
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The Impact of Multidisciplinary Discussion (MDD) in the Diagnosis and Management of Fibrotic Interstitial Lung Diseases by Ghofran Ageely, Carolina Souza, Kaissa De Boer, Saly Zahra, Marcio Gomes, Nha Voduc

“…Relevant change in management including initiation or change in pharmacological treatment, referral to surgical biopsy, and nonpharmacological management were recorded. …”
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Hypomania, Depression, Euthymia: New Evidence in Parkinson’s Disease by Margherita Canesi, Sara Lavolpe, Viviana Cereda, Alessandra Ranghetti, Roberto Maestri, Gianni Pezzoli, Maria Luisa Rusconi

“…Mood state was assessed through the Internal State Scale (ISS) while depressive symptoms were evaluated through the Beck Depression Inventory-II (BDI-II), nonmotor symptoms by means of the Non-Motor Symptoms Scale (NMSS), and the presence of impulse control disorders (ICDs) with the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease (QUIP). Clinical and pharmacological data have also been recorded. No significant differences in mood state distribution between groups were observed. …”
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Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material by Soeun Shin, Seunghee Kim, Jeongho Lee, Hyerim Son, Jin-Hyub Paik, Nadezhda Gennadievna Gemejiyeva, Zhanat Zhumabekovna Karzhaubekova, Taek Lee, Hah Young Yoo

“…Plants of the genus <i>Atraphaxis</i> have been widely used as traditional herbal medicines and are just beginning to be recognized for their pharmacological activities by scientific validation. In particular, <i>Atraphaxis virgata</i> (Regel) Krasn. has not reported even fundamental data, such as antioxidant activity and phytochemical properties, which requires investigation for its medical application. …”
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Screening of Anti-Inflammatory Components of Qin Jin Hua Tan Tang by a Multivariate Statistical Analysis Approach for Spectrum-Effect Relationships by Feipeng Duan, Yisheng Li, Meizhen Zhao, Tianyong Hu, Xinquan Pan, Yue Feng, Fang Ma, Shuqi Qiu, Yiqing Zheng

“…Additionally, the spectrum-effect relationship between the relative areas of the 24 peaks and pharmacological activity was investigated using multivariate statistical analysis. …”
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Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra... by Ying Guo PhD, Peng Yang MS, Zihong Wu PhD, Sanyin Zhang PhD, Fengming You PhD

“…Diels (dang gui) (ARS). Modern pharmacological studies have demonstrated that AR and ARS possess immune-enhancing, anti-tumor, anti-inflammatory, and anti-angiogenic properties. …”
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Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway by Baolong Li, Kaiming Yu, Xiongyao Zhou, Jialu Sun, Le Qi, Weiye Li, Tuo Yang, Weizhen Li, Ningning Wang, Xiaosong Gu, Shusen Cui, Rangjuan Cao

“…Our experimental findings showed that TSPO expression was upregulated during neuropathic pain, accompanied by mitochondrial dysfunction, specifically manifested as impaired mitochondrial biogenesis, disrupted mitochondrial dynamics (including insufficient expression of mitochondrial biogenesis and fusion-related proteins, as well as significantly increased expression of fission-related proteins), and activation of pyroptosis. Pharmacological upregulation of TSPO, but not its downregulation, effectively alleviated SNI-induced pain hypersensitivity, improving mitochondrial function and reducing pyroptosis. …”
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Comprehensive Assessment of Biomolecular Interactions of Morpholine-Based Mixed Ligand Cu(II) and Zn(II) Complexes of 2,2′-Bipyridine as Potential Anticancer and SARS-CoV-2 Agents:... by Karunganathan Sakthikumar, Rui Werner Maçedo Krause, Bienfait Kabuyaya Isamura

“…A new class of pharmacologically active mixed-ligand complexes (1a-2a) [MII(L)2 (bpy)], where L = 2-(4-morpholinobenzylideneamino)phenol), bpy = 2,2′-bipyridine, MII = Cu (1a), and Zn (2a), were assigned an octahedral geometry by analytical and spectral measurements. …”
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Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage by Marin Kuntić, Ivana Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Dilja Krueger-Burg, Huige Li, Sebastian Steven, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber

“…This study provides a novel perspective mitigating the adverse effects of noise pollution, especially in vulnerable groups with medication, a rationale for further pharmacological human studies.…”
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SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject by R. Wumba, M. Mandina, Y. Nlandu, J. R. Makulo, A. Tshimpi, P. Mbala, A. Mbangama, P. Kabututu, J. M. Kayembe

“…Reported data could contribute to a better understanding of molecular mechanisms of cellular infection by SARS-CoV-2 as well as to a more easy explanation of the action of pharmacological agents used for the treatment, while elucidating intimate mechanisms of the immunity of infected subject.…”
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Investigation of biometabolites and novel antimicrobial peptides derived from promising source Cordyceps militaris and effect of non-small cell lung cancer genes computationally. by Muhammad Afzal, Mai Abdel Haleem A Abusalah, Neelum Shehzadi, Muhammad Absar, Naveed Ahmed, Sarmir Khan, Yalnaz Naseem, Noshaba Mehmood, Kirnpal Kaur Banga Singh

“…An in-vitro analysis of biometabolites and antimicrobial peptides was performed to investigate their pharmacological potentials followed by quantification and characterization of extracted protein. …”
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