Management of a Female Patient with Irritable Bowel Syndrome and Somatoform Disorder by E. A. Trush, E. A. Poluektova, A. G. Beniashvili, O. S. Shifrin

“…Kolofort can be the drug of choice both in patients with IBS and the pharmacological part of therapy in patients with somatization disorder.…”
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Antimicrobial resistance of <I>Salmonella</I> isolates recovered from animal products by N. B. Shadrova, O. V. Pruntova, E. A. Korchagina

“…Different Salmonella serovars demonstrated different proportions of susceptible and resistant isolates, in terms of antibiotics from ten pharmacological groups. The largest number of polyresistant isolates was noted in Salmonella serovars S. virchow, S. nigeria, S. infantis, S. colindale. …”
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Nanonization of ethanolic tulsi leaf extract and its major compound eugenol and evaluation of their inhibitory potential against calcium oxalate crystal (a kidney stone component) by Sourav Ghosh, Tarakdas Basu

“…., bare TLE and eugenol; ENP was more potent than TLE-NP with respect to crystallization inhibitory activity, whereas they were comparable in crystal disintegration potency. Future in vivo pharmacological and toxicological studies will surely lead to the development of the TLE-NPs and ENPs as potential therapeutic agents against calcium oxalate pathogenesis.…”
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High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein by Xin Zhang, Hui Chen, Hui Lin, Ronglan Wen, Fan Yang

“…As a consequence of using specific pharmacological, physiological, and ADMET criteria, four new prevailing compounds, NPA000018, NPA000111, NPA00305, and NPA014826, were successfully selected. …”
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Calculation of the molecular properties of five cephalosporins: cephradine, cephalexin, cefadroxil, cefprozil and ceftobiprole by Elso Manuel Cruz Cruz, Eslhey María Sánchez Domínguez

“…<strong>Background:</strong> The side chains attached to the 7-amino cephalosporanic acid, the structural basis of cephalosporin, condition its molecular properties and cause differences in its pharmacological action. Molecular modeling contributes to further knowledge about this relationship. …”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Methods Here, we investigated the potential of Dioscin, a natural compound known for its diverse pharmacological properties, in mitigating ferroptosis in cardiomyocytes following MI by targeting ER stress. …”
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RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection by Ignacio Silva-Llanes, Ignacio Silva-Llanes, Ignacio Silva-Llanes, Enrique Madruga, Enrique Madruga, Ana Martínez, Ana Martínez, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker

“…One of the main challenges of these diseases is that they have neither biomarkers nor pharmacological targets to stop the neurodegenerative process. …”
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Rheumatoid-like hand deformities and aortic valve disease in a 13-year-old girl with homozygous familial hypercholesterolemia: a case report by Anjuman Ara Rahman, Abhijit Datta, Kamal Uddin Ahmed, Anindita Das Barshan, Mohammad Jahid Hasan

“…Early detection allows timely intervention, such as lifestyle modifications and pharmacological treatments, which can significantly reduce these risks. …”
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Comparative Analysis of the Content of Sum of Hydroxycinnamic Acids from Leaves of Actinidia arguta Lindl. Collected in Ukraine and China by Nadiia Kovalska, Uliana Karpiuk, Valentyna Minarchenko, Iryna Cholak, Natalia Zaimenko, Nadiia Skrypchenko, Dejiang Liu

“…Hydroxycinnamic acids (HCAs) are one of the important biologically active substances of A. arguta leaves, which provide the pharmacological action of this raw material. The aim of the study was to identify and compare the quantitative content of HCAs in the leaves of A. arguta harvested in Ukraine and China in different phases of the growing season. …”
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Genome-wide identification of the bHLH gene family in Scutellaria baicalensis and their relationship with baicalin biosynthesis under drought stress by Yingxin Sun, Beier Wang, Lichao Zhang, Xiaohan Zheng, Peng Xu, Meng Zhang, Meiguang Han, Peng Di, Mei Han, Lin Cheng, Limin Yang

“…The bHLH gene family plays a critical role in regulating internal responses in plants. Although the pharmacological properties of Scutellaria baicalensis have been extensively studied, its bHLH gene family remains poorly investigated. …”
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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

“…This review elucidates the pharmacological mechanisms underlying the protective effects of wogonin in CNS diseases, including ischemic stroke, hemorrhagic stroke, traumatic brain injury, epilepsy, anxiety, neurodegenerative diseases, and CNS infections. …”
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Diagnosis and Treatment of Golfer's Elbow: A Review of Therapeutic Approaches by Karol Dzwonnik, Urszula Zelik, Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Wiktoria Domino, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“…Conservative treatment, including rest, physical therapy, and pharmacological support, is the first-line approach. In refractory cases, surgical options like open repair and arthroscopy, along with innovative techniques such as collagen-augmented sutures and stem cell applications, show promising results. …”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2007 Update by Denis E O’Donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy D Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Alan Kaplan, Sean Keenan, Yves Lacasse, Francois Maltais, Jeremy Road, Graeme Rocker, Don Sin, Tasmin Sinuff, Nha Voduc

“…Highlights of this update include new epidemiological information on mortality and prevalence of COPD, which charts its emergence as a major health problem for women; a new section on common comorbidities in COPD; an increased emphasis on the meaningful benefits of combined pharmacological and nonpharmacological therapies; and a new discussion on the prevention of acute exacerbations. …”
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Selective mPGES-1 Inhibitor Ameliorated Adjuvant-Induced Arthritis in the Rat Model by Min Ji Kim, Hwi-Ho Lee, Choi Kim, Ja Yeon Lee, Kyung-Sook Chung, Kyung-Tae Lee, Jae Yeol Lee

“…Therefore, MPO-0144 represents a valuable pharmacological tool for the study of regulation of inducible mPGES-1 in an inflammatory arthritis rat model.…”
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Effects of Anti-Obesity Strategies on Bone Mineral Density: A Comprehensive Meta-Analysis of Randomized Controlled Trials by Myung Jin Kim, Seonok Kim, Han Na Jung, Chang Hee Jung, Woo Je Lee, Yun Kyung Cho

“…At follow-up examination, the BMD of the lumbar spine decreased significantly after metabolic surgery (mean difference [MD]=-0.40 g/cm2; 95% confidence interval [CI], -0.73 to -0.07; I2=0%); lifestyle and pharmacological interventions did not result in a significant decrease in BMD at any location. …”
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Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells by Hyun-Jae Jang, Kang-Hoon Kim, Eun-Jae Park, Jeong A. Kang, Bong-Sik Yun, Seung-Jae Lee, Chan Sun Park, Soyoung Lee, Seung Woong Lee, Mun-Chual Rho

“…Although various pharmacological studies of C. orbiculatus extract has been reported, an anti-inflammatory mechanism study of their phytochemical constituents has not been fully elucidated. …”
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Relationship between secondary metabolites and ecological suitability zones for Eucommia ulmoides. by Ting Yao, Ya Wang, Na Zhang, Beichao Wang, Zhuoting Gan

“…The contents of six pharmacologically active secondary metabolites, including chlorogenic acid, aucubin, geniposidic acid, geniposide, pinoresinol monoglucoside, and pinoresinol diglucoside were measured in the EU bark. …”
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Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist P... by Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw

“…Using a preconstricted preparation of rat tail arterial smooth muscle, a single dose of 10−6 M of the peptide effectively inhibited the dose-dependent relaxation effect of bradykinin between 10−11 M and 10−5 M and subsequently, this effect was pharmacologically-characterized using specific bradykinin B1- (desArg-HOE140) and B2-receptor (HOE140) antagonists; the data from which demonstrated that the antagonism of the novel peptide was mediated through B2-receptors. …”
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Phylogenetic Analysis and Extracellular Enzyme Profiles of Yeast Strains Isolated from Raspberry Fruits by Melih Günay, Tulay Turgut Genc

“…Raspberry fruit contains phenolic compounds, flavones, flavonoids, vitamins, and antioxidant substances that are important properties for health and pharmacological sciences. Edible berries provide also a suitable habitat for the growth of various microorganisms. …”
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The Effects of Six Weeks of Patella Taping on Function, Proprioception, and Balance in Women with Knee Osteoarthritis by Maryam Alikhani, Hamid Tabatabai

“…Patella taping may be an effective non-pharmacological tool for enhancing these outcomes and is recommended for use by sports trainers and physiotherapists.…”
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