Associations between physical activities and self-harm behaviour in depression across the genotype: findings from the UK biobank by Jaegyun Jung, Sangyeon Lee, Jeong Ho Lee, Doheon Lee

“…Background Physical activities are widely implemented for non-pharmacological intervention to alleviate depressive symptoms. …”
Get full text

The effect of regular exercise and vitamin C on hs-cTnT TNF-α levels in obese boys students by Mohammadbagher Forghani Ozrudı, Javad Alızade, Aliakbar Raıespour

“…Therefore the use of non-pharmacological methods, exercise, vitamin C and combination of the above interventions may lead to a reduction of inflammation in obese boy’s students.…”
Get full text

Advancements in Nanomedicine for the Diagnosis and Treatment of Kidney Stones by Wang Y, Yang J, Amier Y, Yuan D, Xun Y, Yu X

“…In clinical diagnosis and management, traditional surgical interventions and pharmacological treatments are primarily utilized; however, these methods possess inherent limitations. …”
Get full text

KaRhab: an international online registry for cardiac rhabdomyomas by Vera-Maria Herrmann, Maria Arelin, Caroline G. Bergner, Julia Herrmann, Paula Janz, Henriette Kiep, Annika Mueller, Steffen Syrbe, Robert Wagner, Bardo Wannenmacher, Nadine Wolf, Michael Weidenbach, Vincent Strehlow

“…The registry should not just provide a comprehensive and informative overview of causes, time course, symptoms and therapeutic options of cardiac RHM but also facilitate information sharing among clinicians and researchers and serve as a basis for future clinical and pharmacological studies.…”
Get full text

Determination of (4E,6E,12E)-Tetradecatriene-8,10-diyne-1,3-diyl Diacetate in Rat Plasma and Tissues by HPLC-UV Method and Their Application to a Pharmacokinetic and Tissue Distrib... by Yan Huo, Yu-Qiang Liu, Zhong-Xu Bai, Qian Cai

“…In order to clarify the influence of processing on pharmacological properties of Atractylodis Rhizoma, an investigation was carried out to compare the pharmacokinetics and tissue distribution of typical constituent after oral administration of raw Atractylodis Rhizoma and processed ones. …”
Get full text

Cardiovascular toxicity of tisagenlecleucel in children and adolescents: analysis of spontaneous reports submitted to FAERS by Ganggang Wang, Lin Su, Yanjun Liu, Xiaohan Yang, Yi Li, Qi Mei, Qi Mei, Wen Gao

“…BackgroundThe advent of tisagenlecleucel has been a major advance in the pharmacological treatment of relapsed/refractory B-cell acute lymphoblastic leukemia in children and adolescents. …”
Get full text

Jusvinza treatment resolution in confirmed COVID-19 patients. Santiago de Cuba, 2021 by Sandra Caridad Laurencio Vallina, Martha María Arias Carbonell, Leonardo Ramos Hechavarría, Dayami Lescay Balanquet, Roger Pina Núñez

“…Some clinical variables (clinical status, associated non-communicable diseases, clinical progression), epidemiological (age, sex) and pharmacological (resolving, duration in days) were analyzed. …”
Get full text

TEAD1‐Mediated Trans‐Differentiation of Vascular Smooth Muscle Cells into Fibroblast‐Like Cells Contributes to the Stabilization and Repair of Disrupted Atherosclerotic Plaques... by Ming Zhai, Zhijun Lei, Yefei Shi, Jiayun Shi, Yanxi Zeng, Shiyu Gong, Weixia Jian, Jianhui Zhuang, Qing Yu, Mark W. Feinberg, Wenhui Peng

“…In vivo experiments using a TS model of plaque rupture demonstrated that TEAD1 played a crucial role in promoting plaque stability and healing post‐rupture through pharmacological or TEAD1‐AAV treatments. Mechanistically, it is found that TEAD1 promoted the expression of fibroblast markers through the Wnt4/β‐Catenin pathway, facilitating the trans‐differentiation. …”
Get full text

The effects of intermittent fasting on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with rheumatoid arthritis: a randomized... by Aryan Tavakoli, Camellia Akhgarjand, Hastimansooreh Ansar, Hirad Houjaghani, Amirhossein Khormani, Kurosh Djafarian, Abdolrahman Rostamian, Mahsa Ranjbar, Gholamreza Mohammadi Farsani

“…These findings suggest that IF may be an effective non-pharmacological intervention for managing RA in this population, potentially addressing both primary disease symptoms and associated metabolic complications. …”
Get full text

Mifepristone Accelerates HPA Axis Recovery in Secondary Adrenal Insufficiency by Pejman Cohan

“…Transient secondary adrenal insufficiency (SAI) is an expected complication following successful adenomectomy of ACTH-secreting pituitary adenomas or unilateral adrenalectomy for cortisol-secreting adrenal adenomas. To date, no pharmacological therapy has been shown to hasten recovery of the hypothalamic-pituitary-adrenal (HPA) axis in this clinical scenario. …”
Get full text

RETRACTED: A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice by Shireen Mohammad, Sura Al Zoubi, Sura Al Zoubi, Debora Collotta, Nadine Krieg, Nadine Krieg, Bianka Wissuwa, Bianka Wissuwa, Gustavo Ferreira Alves, Gareth S. D. Purvis, Gareth S. D. Purvis, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Andrea Baragetti, Andrea Baragetti, Alberico Luigi Catapano, Alberico Luigi Catapano, Alberico Luigi Catapano, Egle Solito, Egle Solito, Elisabeth Zechendorf, Tobias Schürholz, Wilmar Correa-Vargas, Klaus Brandenburg, Sina M. Coldewey, Sina M. Coldewey, Massimo Collino, Muhammad M. Yaqoob, Lukas Martin, Lukas Martin, Christoph Thiemermann

Get full text

Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease by Elisa Rubino, Maria Italia, Elisa Giorgio, Silvia Boschi, Paola Dimartino, Tommaso Pippucci, Fausto Roveta, Clara Maria Cambria, Gabriella Elia, Andrea Marcinnò, Salvatore Gallone, Ekaterina Rogaeva, Flavia Antonucci, Alfredo Brusco, Fabrizio Gardoni, Innocenzo Rainero

Get full text

Testosterone-Induced Effects on Lipids and Inflammation by Stella Vodo, Nicoletta Bechi, Anna Petroni, Carolina Muscoli, Anna Maria Aloisi

Get full text

Fractional amplitude of low-frequency fluctuations during music-evoked autobiographical memories in neurotypical older adults by Teresa Lesiuk, Kaitlyn Dillon, Giulia Ripani, Ioannis Iliadis, Gabriel Perez, Bonnie Levin, Xiaoyan Sun, Roger McIntosh

“…IntroductionResearchers have shown that music-evoked autobiographical memories (MEAMs) can stimulate long-term memory mechanisms while requiring little retrieval effort and may therefore be used in promising non-pharmacological interventions to mitigate memory deficits. …”
Get full text

Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI by Leonardo De Luca, Furio Colivicchi, Domenico Gabrielli, Donata Lucci, Gabriele Grippo, Francesco Piemonte, Bruno Villari, Andrea Di Lenarda, Fabrizio Oliva, Michele Massimo Gulizia

“…Our data suggest that patients with multiple MIs managed by cardiologists in routine clinical practice present an incremental clinical risk, more frequently undergo coronary angiography, and are more intensively managed with pharmacological therapies compared to patients at their first MI episode.…”
Get full text

Research on treatment-related aspects of depression from India in the preceding decade (2014–2023): An updated systematic review by Alankrit Jaiswal, S Umesh, Nishant Goyal

“…Studies on ketamine have been inconclusive, and existing research on pharmacological agents is limited. Neuro-modulation studies show promise, but larger-scale studies are needed. …”
Get full text

From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

“…By integrating traditional medicinal knowledge with modern scientific insights, this review underscores L. barbarum’s potential as a functional food and therapeutic agent. Its unique pharmacological properties and broad applicability position it as a valuable tool for health promotion and disease prevention, while highlighting areas requiring further research to optimise its safe and effective use.…”
Get full text

Upper Extremity Superficial Vein Thromboses Presenting as Acute Neck Pain in a Young and Healthy Male: A Case Report by Kristen L Zosel, Max K Dummar, Benjamin G Adams, Nancy C Henderson, Richard B Westrick

“… # Outcomes The subject underwent a D-dimer, Doppler ultrasound, pharmacological treatment of Rivaroxaban, and was referred to hematology/oncology to rule out systemic causes of SVTs. …”
Get full text

General views on treatment technologies for patients with incisional ventral hernia by E. E. Lukoyanychev, S. G. Izmajlov, V. A. Emelyanov, O. S. Kolchina, A. I. Rotkov, M. N. Kiselyov

“…The introduction of new methods of hernia repair based on the uncontrolled separation of the anatomical structures of the abdominal wall imposes special requirements on surgical technology: plastic material, instrumental and technical support, wound closure and pharmacological support, especially in conditions of increased intra-abdominal pressure and tissue tension. …”
Get full text

Effect of Matrine on growth performance, gut health, and gut microbiota in chickens infected with avian pathogenic Escherichia coli by Ningning Mao, Yaming Yu, Jiqin Cui, Jin He, Yang Yang, Deyun Wang

“…Matrine, a natural component derived from Sophora flavescens, exhibits various pharmacological effects, including anti-inflammatory and antioxidant activities. …”
Get full text