Sex differences in the peripheral levels of cytokines during 12-month antipsychotic treatment in a drug-naïve schizophrenia spectrum cohort by I. Ratke, A. Torsvik, C.A. Bartz-Johannessen, F. Fathian, I. Joa, S.M. Klæbo Reitan, E.M. Løberg, M. Rettenbacher, S. Skrede, V.M. Steen, E. Johnsen, R.A. Kroken

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Integrating network analysis and experimental validation to reveal the mechanism of Cuscuta chinensis lam. Extract in the treatment of IgA nephropathy by Xianlong Zhang, Mingjie Liang, Ziyang Lin, Minyi Li, Tingting Duan, Yun Han, Lanqing Meng, Mengqiu Li, Guixuan Lin, Tao Xia, Ying Lai, Boen Liang, Bingqiong Li, Minhua Li, Fengxin Kang, Quan Zhu, Zhenghai Li, Junzheng Yang

“…Methods: A network pharmacology analysis was employed to examine the interactions between the active ingredients and core targets, with a view to elucidating the possible potential mechanisms in Cuscuta chinensis Lam. extract (CCLE) in the treatment of IgA nephropathy. …”
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases by Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Villegas, Jarosław Olav Horbanczuk, Ozlen Konu, Isabel Lastres-Becker, Anna-Liisa Levonen, Viktorija Maksimova, Charalambos Michaeloudes, Liliya V. Mihaylova, Michel Edwar Mickael, Irina Milisav, Biljana Miova, Patricia Rada, Marlene Santos, Miguel C. Seabra, Dubravka Svob Strac, Sandra Tenreiro, Ioannis P. Trougakos, Albena T. Dinkova-Kostova

“…Thus, it is possible that a single pharmacological NRF2 modulator might mitigate the effect of the main hallmarks of NCDs, including oxidative, proteostatic, inflammatory and/or metabolic stress. …”
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The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion by Maja Reimann, Korkut Avsar, Andrew DiNardo, Torsten Goldmann, Gunar Günther, Michael Hoelscher, Elmira Ibraim, Barbara Kalsdorf, Stefan Kaufmann, Niklas Köhler, Anna Mandalakas, Florian Maurer, Marius Müller, Dörte Nitschkowski, Ioana Olaru, Cristina Popa, Andrea Rachow, Thierry Rolling, Helmut Salzer, Patricia Sanchez-Carballo, Maren Schuhmann, Dagmar Schaub, Victor Spinu, Elena Terhalle, Markus Unnewehr, Nika Zielinski, Jan Heyckendorf, Christoph Lange

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Development, validation, and clinical application of a machine learning model for risk stratification and management of cervical cancer screening based on full-genotyping hrHPV tes... by Binhua Dong, Zhen Lu, Tianjie Yang, Junfeng Wang, Yan Zhang, Xunyuan Tuo, Juntao Wang, Shaomei Lin, Hongning Cai, Huan Cheng, Xiaoli Cao, Xinxin Huang, Zheng Zheng, Chong Miao, Yue Wang, Huifeng Xue, Shuxia Xu, Xianhua Liu, Huachun Zou, Pengming Sun

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Level-8 Ph.D. Programs In Medical Sciences: High Time For The Higher Education Commission (HEC) Of Pakistan To Establish A Medical Wing by Wafa Omer

“…The medical universities in Pakistan have started launching PhD programs in Basic and Diagnostic Medical Sciences and the trend towards opting for these prestigious programs is on the rise amongst the young physicians.3 The subjects being offered for pursuing PhD in the medical sciences by most of the medical universities across Pakistan are Anatomy, Physiology, Biochemistry, Pharmacology, Chemical Pathology, Haematology, Microbiology, Histopathology and Community Medicine. …”
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East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol by Michael Doherty, Roshan das Nair, Ana Valdes, Reuben Ogollah, Paul Greenhaff, Bonnie Millar, Michelle Hall, Amy Fuller, Polykarpos Angelos Nomikos, David A Walsh, A Abhishek

“…This study aims to develop a complex intervention with non-pharmacological and pharmacological components that can be delivered by nurses. …”
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Phytochemistry and Biological Activities of Poria by Jie Lu, Jing Tian, Li Zhou, Lijun Meng, Sitan Chen, Changyang Ma, Jinmei Wang, Zhenhua Liu, Changqin Li, Wenyi Kang

“…In this paper, we reviewed the literature, summarized the main compound types, and reviewed in detail their pharmacological effects in antitumor, immunomodulatory, effects on kidney, hepatoprotective activity, effects on blood sugar, antioxidant effects, anti-inflammatory effects, effects on the gut, antidepressant, and so on, and also categorized the compounds with the same or similar pharmacological effects to provide a reference for the in-depth study of the material basis of the pharmacological effect, quality standards, and pharmacological activity of Poria.…”
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The theses for MD degree by article Editorial

“…Mikhailova — Gastroesophageal reflux disease: comparative efficacy of non-pharmacological and pharmacological treatments.…”
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Treatment of Anxiety Disorders and Comorbid Alcohol Abuse with Buspirone in a Patient with Antidepressant-Induced Platelet Dysfunction: A Case Report by Mir Mazhar, Tariq Hassan, Tariq Munshi

“…The risk of abnormal bleeding with serotonin reuptake inhibitors has been known, but there is insufficient evidence base to guide pharmacological treatment of anxiety in patients with underlying haematological conditions. …”
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Protocol for a meta-review of interventions to prevent and manage ICU delirium by Andrew Booth, Maria Pufulete, Ben Gibbison, Burak Kundakci, Katherine Louise Jones

“…We will include all critically ill adults (aged≥18 years) and any ICU delirium prevention or management intervention (pharmacological or non-pharmacological). For pharmacological interventions, we will include reviews of RCTs. …”
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Conjugation of Daunorubicin to Monoclonal Antihuman Sarcoma Antibody by a Novel Method by Michel Pagé, Denis Thibeault, Hélène Tremblay, Christiane Noël, Marie-Josée Perron

“…Most of the reported methods for coupling anthracycline drugs to antibody result in either a loss of pharmacological activity or yield antibodies which have lost much of their immunological specificity. …”
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Neuropsychiatric symptoms in Alzheimer’s disease by J. Vegytė, R. Podėnė, E. Dlugauskas, A. Vaitkevičius

“…It is recommended that neuropsychiatric symptoms should be treated through a combined approach using pharmacological and non-pharmacological measures. …”
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Do maternal haemodynamics have a causal influence on treatment for gestational diabetes? by Abigail R. Anness, Michael Foster, Mohammed W. Osman, David Webb, Thompson Robinson, Asma Khalil, Neil Walkinshaw, Hatem A. Mousa

“…No significant causal relationships were found between maternal haemodynamics and the need for pharmacological treatment.…”
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Flowers: precious food and medicine resources by Xuqiang Liu, Senye Wang, Lili Cui, Huihui Zhou, Yuhang Liu, Lijun Meng, Sitan Chen, Xuefeng Xi, Yan Zhang, Wenyi Kang

“…This paper summarizes the active ingredients, pharmacological activities and applications in the pharmaceutical and food industries of flower plants in recent years. …”
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The role of Kegel exercises in reducing involuntary loss of urine in Overactive Bladder and Mixed Urinary Inconti-nence by Lucian Șerbanescu, Vadym Rotar, Elena-Valentina Ionescu, Alexandra-Ecaterina Ciota, Sebastian Mirea, Paris Ionescu, Andreea Cristina Costea

“…The participants were monitored for six months: In the first three months received only pharmacological therapy, solifenacin succinate 10 mg per day, and after this period the same group associated to the pharmacological treatment daily Kegel exercises. …”
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The Role of Anethum graveolens L. (Dill) in the Management of Diabetes by Mohammad Taghi Goodarzi, Iraj Khodadadi, Heidar Tavilani, Ebrahim Abbasi Oshaghi

“…The aim of the present paper was to summarize pharmacological effects of AG in the management of diabetes. …”
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Treatment-Emergent Mania in a Prepubertal Boy by Dulangi Maneksha Amerasinghe Dahanayake, Gampolage Swarna Wijetunge

“…This case highlights the need for further research into the presentations and pharmacological management of prepubertal children with bipolar affective disorder.…”
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Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents by Robert J. Gillies, John M. Hoffman, Kit S. Lam, Anne E. Menkens, David R. Piwnica-Worms, Daniel C. Sullivan, Ralph Weissleder

“…Combinatorial chemistry and high-throughput screening have become standard tools for discovering new drug candidates with suitable pharmacological properties. Now, those same technologies are starting to be applied to the problem of discovering novel in vivo imaging agents. …”
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Chronic obstructive pulmonary disease from the perspective of medicine based on evidence. by Gerardo Rivero González, Rolando Delgado Figueredo, Iris González Morales

“…This article made on bibliographical revision shows the main therapeutics pharmacological and non pharmacological options used in case of an acute decompensation of this disease based on the main available evidences. …”
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