Eicosapentaenoic Acid Supplementation Changes Fatty Acid Composition and Corrects Endothelial Dysfunction in Hyperlipidemic Patients by Ken Yamakawa, Michio Shimabukuro, Namio Higa, Tomohiro Asahi, Kageyuki Ohba, Osamu Arasaki, Moritake Higa, Yoshito Oshiro, Hisashi Yoshida, Tohru Higa, Taro Saito, Shinichiro Ueda, Hiroaki Masuzaki, Masataka Sata

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Normothermic Crystalloid Polarizing Cardioplegia Improves Systolic and Diastolic Function in a Porcine Model of Cardiopulmonary Bypass by David Santer, Stefan Heber, Anne-Margarethe Kramer, Judith Radloff, Katharina Heissl, Attila Kiss, David J. Chambers, Seth Hallström, Bruno K. Podesser

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Trends in the Use of Sphingosine 1 Phosphate in Age-Related Diseases: A Scientometric Research Study (1992-2020) by Qiong He, Gaofeng Ding, Mengyuan Zhang, Peng Nie, Jing Yang, Dong Liang, Jiaqi Bo, Yi Zhang, Yunfeng Liu

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Exploring similarities and differences in anti-atherosclerotic potential bioactives among Dendrobium species by UPLC-Q-Exactive Orbitrap MS by Yu Zhang, Xi Chen, Oushan Tang, Keyun Cheng, Lijun Ge, Weibo Lu, Jing Zheng, Yeshun Wu, Si-wei Wang, Xi-xi Zeng, Jing Xue, Yiwei Cui, Liting Ji, Qing Shen

“…The chemical composition of D. fimbriatum, D. officinale, D. devonianum, D. gratiosissimum, and D. catenatum was analyzed using UPLC-Q-Exactive Orbitrap MS. Network pharmacology predicted the pharmacological basis and molecular mechanisms. …”
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Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT... by Huizhen Xing, Xinwei Bai, Xiaoying Pei, Yuqi Zhang, Xueying Zhang, Shujun Chen, Dan Li, Bin Lv, Xiaoying Wang, Xiaoli Wu

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Plasma Metabolite Profiles of Healthy Volunteers after Administration of a Thai Herbal Formula for Dizziness by Ranida Boonrak, Kajee Pilakasiri, Suksalin Boonranasubkajorn, Natchagorn Lumlerdkij, Pravit Akarasereenont

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Investigating the antioxidant and anti-inflammatory potential of Nypa fruticans: a multifaceted approach to skin protection and aging by Seul Ki Kim, Sang-Back Kim, Seul Bi Lee, Kang sub Kim, So-Ri Son, En Jin Choi, Byung Chul Park, Eunyoung Hong, You Ah Kim, Byoung Seok Moon, Sullim Lee

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Comparing propofol anaesthesia guided by Bispectral Index monitoring and frontal EEG wave analysis with standard monitoring in laparoscopic surgery: protocol for the ‘EEG in Genera... by Luzius A Steiner, Salome Dell-Kuster, Bettina U Gruber, Valerie Girsberger, Lukas Kusstatscher, Simon Funk, Anita Luethy, Lien Jakus, Julien Maillard, Christoph S Burkhart

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Abnormalities in Blood Parameters in Athletes Taking Anabolic Androgenic Steroidal Agents; an Observational Clinical Study by Mubarak GS, Bamagous GA, Alsanosi SM, Alhindi YZ, Alqashqari HS, Albar HT, Siddiqi AM, Ayoub N, Falemban AH

“…Ghaida Siraj Mubarak,1 Ghazi A Bamagous,2 Safaa M Alsanosi,2 Yosra Z Alhindi,2 Hamsah S Alqashqari,3 Halah Tariq Albar,4 Ahmed M Siddiqi,5 Nahla Ayoub,2 Alaa H Falemban2 1Pharmacy Department, Hera’ General Hospital, Ministry of Health, Makkah, Saudi Arabia; 2Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia; 3Department of Community Medicine and Pilgrims Health Care, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia; 4Department of Physiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia; 5Department of Internal Medicine, National Guard Hospital, Jeddah, Saudi ArabiaCorrespondence: Alaa H Falemban, Email ahfalemban@uqu.edu.saBackground: Many studies indicate that high and multiple doses of anabolic-androgenic steroids (AAS) for athletic enhancement can result in serious and irreversible adverse effects. …”
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Cognitive and Emotional Empathy in Individuals with Spinal Cord Injury by Veronica Guadagni, Marco Sarà, Massimiliano Conson, Antonio Carolei, Simona Sacco, Silvia Vadini, Caterina Pistarini, Arcangelo Barbonetti, Giuseppe Iaria, Francesca Pistoia

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The Influence of Various Morphologic and Hemodynamic Carotid Plaque Characteristics on Neurological Events Onset and Deaths by Milan D. Brajovic, Nataša Markovic, Goran Loncar, Nikola Šekularac, Dejan Kordic, Nebojša Despotovic, Predrag Erceg, Branislav Donfrid, Zvezdan Stefanovic, Milica Bajcetic, Ljiljana Brajovic, Živorad Savic

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Reduced Presence of SARS-CoV-2 microRNA-like Small RNA in the Serum of Patients with Post-Acute Sequelae SARS-CoV-2 Infection by Maria Alfreda Stincarelli, Isabella Abbate, Giulia Matusali, Michele Tanturli, Marta Camici, Rosaria Arvia, Elisabetta Lazzari, Eleonora Cimini, Alessandra Vergori, Fabrizio Maggi, Simone Giannecchini

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The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score – Follow-up of ESTO1-Trial by Eemil Lehtonen, Maiju Vertanen, Heimo Syvälä, Teemu Tolonen, Seppo Auriola, Teuvo Tammela, Aino Siltari, Teemu Murtola

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Gambaran Pengetahuan Remaja Puteri Terhadap Nyeri Haid (Dismenore) dan Cara Penanggulangannya by Erlina Rustam

“…The main action taken is non-pharmacological measures (17.86%). In Pharmacology female adolescents using traditional medicine is a betel leaf (67.00%). …”
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The Influence of Heavy Metals and Trace Elements on Comatose Patients with Severe Traumatic Brain Injury in the First Week of Admission by Bahia Belatar, Abdallah Elabidi, Malika Barkiyou, Mamoun El Faroudi, Rachid Eljaoudi, Laila Lahlou, Saad Kabbaj, Wajdi Maazouzi

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Computational and experimental exploration of morpholine pendent 2-hydrazineyl thiazole: Insights from DFT, ADME profiling, antifungal efficacy and molecular docking analyses by Vishnu A. Adole, I.Antony Danish, J.Jebasingh Kores, J.Winfred Jebaraj, S. Janani, Suresh K. Ghotekar, Rakesh D. Amrutkar

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Chemical Composition and Antimicrobial Activity of Subcritical CO2 Extract of Lepidium latifolium L. (Brassicaceae) by Balzhan B. Azimkhanova, Gulbaram O. Ustenova, Kamalidin O. Sharipov, Kayrolla D. Rakhimov, Galiya M. Sayakova, Ardak B. Jumagaziyeva, Elena V. Flisyuk, Nadezhda G. Gemejiyeva

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Platycodin D inhibits tumor proliferation by modulating macrophage polarization through promoting JAK2 ubiquitination by Wei Wu, Jie Zhang, Zijiao Wang, Chuan Cheng, Dongdong Yuan, Li Peng, Le Li

“…PD also downregulated M2 macrophage markers, impaired mitochondrial function, reduced ROS production, and diminished the tumor-promoting functions of TAMs. Through network pharmacology and experimental validation, STAT3 was identified as a central target. …”
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Safety and efficacy of sugammadex in management of patients with myasthenia gravis undergoing general anesthesia: A systematic review by Alan D. Kaye, Emily A. Villafarra, Erin S. Everett, Erin E. Ware, Sydney A. Mashaw, William D. Brouillette, Camille G. Elder, Taylor Moss, Luke Muiznieks, Edwin Herron, Shahab Ahmadzadeh, Sahar Shekoohi

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Alginate-Based Hydrogels with Amniotic Membrane Stem Cells for Wound Dressing Application by Fitriani N, Wilar G, Narsa AC, Elamin KM, Wathoni N

“…Nurul Fitriani,1,2 Gofarana Wilar,3 Angga Cipta Narsa,2 Khaled M Elamin,4 Nasrul Wathoni1 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 2Pharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda, 75119, Indonesia; 3Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, 45363, Indonesia; 4Graduate School of Pharmaceutical Sciences, Kumamoto University, Chuo-ku, Kumamoto, 862-0973, JapanCorrespondence: Nasrul Wathoni, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia, Tel/Fax +6222 842 888888, Email nasrul@unpad.ac.idObjective: Chronic wounds are a common clinical problem that necessitate the exploration of novel regenerative therapies. …”
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