Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis by Michael P. Salna, Hannah M. Singer, Ali N. Dana

“…Moreover, elderly patients are prone to pharmacologic interactions due to multiple medications. …”
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GABAergic Neuronal Precursor Grafting: Implications in Brain Regeneration and Plasticity by Manuel Alvarez Dolado, Vania Broccoli

“…Numerous neurological disorders are caused by a dysfunction of the GABAergic system that impairs or either stimulates its inhibitory action over its neuronal targets. Pharmacological drugs have generally been proved very effective in restoring its normal function, but their lack of any sort of spatial or cell type specificity has created some limitations in their use. …”
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Drugs from poisonous plants: Ethnopharmacological relevance to modern perspectives by Bhagya Lakhmi Rajbongshi, Ashis K. Mukherjee

“…This review accentuates the need for rigorous scientific investigations, prior to clinical trials to validate their traditional uses, which would reveal the pharmacological interventions that will eventually advance human health and well-being.…”
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Motor-Skill Learning Is Dependent on Astrocytic Activity by Ragunathan Padmashri, Anand Suresh, Michael D. Boska, Anna Dunaevsky

“…To test the hypothesis that astrocytic activity is necessary for motor-skill learning, we perturbed astrocytic function using pharmacological and genetic approaches. We find that perturbation of astrocytes either by selectively attenuating IP3R2 mediated astrocyte Ca2+ signaling or using an astrocyte specific metabolic inhibitor fluorocitrate (FC) results in impaired motor-skill learning of a forelimb reaching-task in mice. …”
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Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside by Sidra Tabassum, Silin Wu, Chang-Hun Lee, Bosco Seong Kyu Yang, Aaron M. Gusdon, Huimahn A. Choi, Xuefang S. Ren

“…We also evaluate various preclinical studies exploring pharmacological agents, gene therapy, and novel drug delivery systems designed to protect and restore mitochondrial function. …”
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Plant Sources, Extraction Methods, and Uses of Squalene by M. Azalia Lozano-Grande, Shela Gorinstein, Eduardo Espitia-Rangel, Gloria Dávila-Ortiz, Alma Leticia Martínez-Ayala

“…It is considered a molecule with pharmacological, cosmetic, and nutritional potential. …”
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Phoenix dactylifera L. (date palm) fruit extracts and fractions exhibit anti-proliferative activity against human pancreatic cancer cell lines by Reem A. Al Alawi, Jörg D. Hoheisel, Mohamed Saiel Saeed Alhamdani, Younis Baqi

“…The prepared date fruit extracts and fractions were pharmacologically evaluated on three pancreatic cancer cell lines: PT45P1, PANC-1, and SUIT-2. …”
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DENTAL ANXIETY – A PSYCHOSOCIAL CAUSE AFFECTING THE QUALITY OF LIFE – A SYSTEMATIC REVIEW by Andreea Sălcudean, Laria-Maria Trușculescu, Ramona Amina Popovici, Nicoleta Șerb, Ciprian Pașca, Cristina Raluca Bodo, Ramona Elena Crăciun, Iustin Olariu

“…Effective management strategies, including non-pharmacological approaches such as cognitive-behavioral therapy and relaxation techniques, have been shown to alleviate anxiety and improve patient outcomes. …”
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Standardized Application of Laxatives and Physical Measures in Neurosurgical Intensive Care Patients Improves Defecation Pattern but Is Not Associated with Lower Intracranial Press... by Martin Kieninger, Barbara Sinner, Bernhard Graf, Astrid Grassold, Sylvia Bele, Milena Seemann, Holger Künzig, Nina Zech

“…After the implementation of the SOP patients suffering from a neurosurgical disorder received pharmacological and nonpharmacological measures to improve bowel movements in a standardized manner within the first 5 days after admission to the intensive care unit (ICU) starting on day of admission. …”
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The Development and Application of Novel IR and NMR-Based Model for the Evaluation of Carminative Effect of Artemisia judaica L. Essential Oil by Muhammed Alzweiri, Ibrahim M. Alrawashdeh, Sanaa K. Bardaweel

“…Furthermore, owing to its sensitivity, our model provides a fundamental basis for the pharmacological assessment of trace amounts of oils with high precision and accuracy.…”
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Effect of Phenylephrine on the Accommodative System by José J. Esteve-Taboada, Antonio J. Del Águila-Carrasco, Paula Bernal-Molina, Teresa Ferrer-Blasco, Norberto López-Gil, Robert Montés-Micó

“…Researchers have traditionally faced the challenge of measuring the accommodative properties of the eye through a small pupil and thus have relied on pharmacological agents to dilate the pupil. Achieving pupil dilation (mydriasis) without affecting the accommodative ability of the eye (cycloplegia) could be useful in many clinical and research contexts. …”
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The Efficacy and Safety of Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pain in Patients with Pancreatic Cancer by Anna Wiechowska-Kozłowska, Klaudiusz Boer, Maciej Wójcicki, Piotr Milkiewicz

“…Twenty nine subjects with unresectable pancreatic cancer and severe pain despite pharmacological treatment underwent EUS-guided celiac plexus neurolysis with 98% ethanol. …”
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Injectable hydrogel regulates immune infiltration through physical and chemical synergy in the treatment of steroid-induced osteonecrosis of the femoral head by Zherui Fu, Yiwen Xu, Fangqi Xu, Haoyu Zhou, Na Lin, Ning Zhang, Feng Lin

“…This treatment was designed to prevent the infiltration of Th17 cells by regulating the physiological function of stem cells and blocking the negative effect of Th17 cells on stem cells pharmacologically. Thus, the dual synergistic regulation of immune infiltration at the lesion site of SONFH enhanced the physiological activity and function of the stem cells, thereby improving the therapeutic effect of SONFH. …”
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Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish by Ilse Bollaerts, Jessie Van houcke, An Beckers, Kim Lemmens, Sophie Vanhunsel, Lies De Groef, Lieve Moons

“…In contrast to mammals, zebrafish retain high regenerative capacities into adulthood and thus form a powerful model to study the contribution of neuroinflammation to successful regeneration. Here, we used pharmacological immunosuppression methods to study the role of microglia/macrophages during optic nerve regeneration in adult zebrafish. …”
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Using Protein Painting Mass Spectrometry to Define Ligand Receptor Interaction Sites for Acetylcholine Binding Protein by Alexandru Graur, Natalie Erickson, Nadine Kabbani

“…Nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion channels expressed in nervous and non-nervous system tissue important for memory, movement, and sensory processes. The pharmacological targeting of nAChRs, using small molecules or peptides, is a promising approach for the development of compounds for the treatment of various human diseases including inflammatory and neurogenerative disorders such as Alzheimer’s disease. …”
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A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery by Yingying Hong, Hongzhe Li, Yang Sun, Yinghong Ji

“…Despite the absence of curative pharmacologic treatment, phacoemulsification with intraocular lens implantation to deal with opacification in the lens is preferred due to the considerable visual outcomes. …”
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DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis by Victoria A. Ismail, Meg Schuetz, Zak N. Baker, Jean A. Castillo-Badillo, Teri V. Naismith, David J. Pagliarini, David J. Kast

“…Here we show that DFCP1 regulates lipid metabolism by directly modulating the activity of Adipose Triglyceride Lipase (ATGL/PNPLA2), the rate-limiting lipase driving the catabolism of LDs. We show through pharmacological inhibition of key enzymes associated with LD metabolism that DFCP1 specifically regulates lipolysis and, to a lesser extent, lipophagy. …”
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Model Analytical Development for Physical, Chemical, and Biological Characterization of Momordica charantia Vegetable Drug by Deysiane Oliveira Brandão, Geovani Pereira Guimarães, Ravely Lucena Santos, Fernando José de Lima Ramos Júnior, Karla Monik Alves da Silva, Fabio Santos de Souza, Rui Oliveira Macêdo

“…Momordica charantia is a species cultivated throughout the world and widely used in folk medicine, and its medicinal benefits are well documented, especially its pharmacological properties, including antimicrobial activities. …”
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Pain Management of Pediatric Musculoskeletal Injury in the Emergency Department: A Systematic Review by Sylvie Le May, Samina Ali, Christelle Khadra, Amy L. Drendel, Evelyne D. Trottier, Serge Gouin, Naveen Poonai

“…Electronic databases were searched systematically for randomized controlled trials of pharmacological and nonpharmacological interventions for children aged 0–18 years, with musculoskeletal injury, in the emergency department. …”
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Lithium Improves Survival of PC12 Pheochromocytoma Cells in High-Density Cultures and after Exposure to Toxic Compounds by Cinzia Fabrizi, Stefania De Vito, Francesca Somma, Elena Pompili, Angela Catizone, Stefano Leone, Paola Lenzi, Francesco Fornai, Lorenzo Fumagalli

“…Taken together these data indicate that pharmacological activation of autophagy allows for the survival of Pheochromocytoma cells in stressful conditions such as high-density cultures and exposure to toxins.…”
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