A critical review on phytochemical profile and health promoting effects of mung bean (Vigna radiata) by Kumar Ganesan, Baojun Xu

“…Botanical, phytochemical and pharmacological information was gathered and orchestrated. …”
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Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms by Jane C. Caldwell, Marina V. Evans, Kannan Krishnan

“…Physiologically based Pharmacokinetic (PBPK) models are used for predictions of internal or target dose from environmental and pharmacologic chemical exposures. Their use in human risk assessment is dependent on the nature of databases (animal or human) used to develop and test them, and includes extrapolations across species, experimental paradigms, and determination of variability of response within human populations. …”
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Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives by Amit Pithadia, Jeffrey R. Brender, Carol A. Fierke, Ayyalusamy Ramamoorthy

“…Natural products are a class of compounds with interesting pharmacological properties against amyloids which have made them interesting targets to study hIAPP. …”
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Effect of Gegen Qinlian Decoction on Cardiac Gene Expression in Diabetic Mice by Jing Han, Zhenglin Wang, Wei Xing, Yueying Yuan, Yi Zhang, Tiantian Lv, Hongliang Wang, Yonggang Liu, Yan Wu

“…The aim of this research is to investigate the therapeutic effect of GGQL decoction on cardiac dysfunction and elucidate the pharmacological mechanisms. db/db mice were divided into DB group or GGQL group, and WT mice were used as control. …”
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Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment by Lily Nahidi, Andrew S. Day, Daniel A. Lemberg, Steven T. Leach

“…Although several pharmacological approaches are used to modulate the inflammatory response in IBD, few lead to histological healing and most have side effects. …”
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Exercise as an Adjuvant Therapy for Hematopoietic Stem Cell Mobilization by Russell Emmons, Grace M. Niemiro, Michael De Lisio

“…HSPC collection protocols rely on pharmacological agents to mobilize HSPCs to peripheral blood. …”
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Authentication of Processed Epimedii folium by EA-IRMS by Fengyan He, Mengyi Li, Yi He, Zhe Dong, Jin Cao, Zhong Dai, Shuangcheng Ma

“…It has been reported that processing EF with mutton fat could improve the bioavailability and intestinal absorption of epimedium flavonoids and thus enhances the pharmacological effects. For economic benefits, it is possible to adulterate processed EF with unprocessed drug or process EF with cheaper plant oils. …”
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Innovative Diagnostic Approaches and Treatment Strategies for Endometriosis: Current Trends and Future Direction - Review by Wiktoria Domino, Joanna Śnieżna, Wojciech Florczak, Karol Dzwonnik, Urszula Zelik, Jagienka Włodyka, Gabriela Trestka, Maria Przygoda, Jakub Dziewic, Kamila Stępień, Sabina Adamczyk

“…Depending on individual needs, various treatment methods are available, including pharmacological and surgical approaches. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate symptoms, while hormonal therapies, such as combined oral contraceptives, GnRH agonists, and progestogens, aim to inhibit ovulation and estrogen production to reduce inflammation and slow disease progression. …”
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Treatment of Nonalcoholic Steatohepatitis in Adults: Present and Future by S. Gitto, G. Vitale, E. Villa, P. Andreone

“…However, because this approach has several limitations, such as a lack of compliance, the use of many drugs has been proposed. The first-line pharmacological choices are vitamin E and pioglitazone, both showing a positive effect on transaminases, fat accumulation, and inflammation. …”
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Treatment of gouty lumbar spinal stenosis: a case report and bioinformatics analysis by Xiao Zhang, Wenbo Gu, Di Luo, Xi Zhu, Xusheng Li, Haifeng Yuan

“…A combined surgical and pharmacological treatment plan has a favorable prognosis. …”
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Transient receptor potential channels in dental inflammation and pain perception: A comprehensive review by Varunya Chantadul, Nattapon Rotpenpian, Tawepong Arayapisit, Aree Wanasuntronwong

“…These inflammatory conditions notably contribute to oral health challenges, often leading to sharp pain, dull aches, and compromised functionality. Pharmacological interventions and emerging strategies aimed at modulating TRP channel activity are critically evaluated. …”
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Pseudorabies virus infection triggers pUL46-mediated phosphorylation of connexin-43 and closure of gap junctions to promote intercellular virus spread. by Alexander Tishchenko, Nicolás Romero, Cliff Van Waesberghe, Jonas L Delva, Oliver Vickman, Gregory A Smith, Thomas C Mettenleiter, Walter Fuchs, Barbara G Klupp, Herman W Favoreel

“…Consequently, a UL46null PRV mutant is unable to phosphorylate Cx43 or inhibit GJIC and displays reduced intercellular spread, which is effectively rescued by pharmacological inhibition of GJIC. Intercellular spread of UL46null PRV is also rescued by inhibition of the stimulator of interferon genes (STING), suggesting that pUL46-mediated suppression of GJIC contributes to intercellular virus spread by hindering intercellular communication that activates STING. …”
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Progress in Therapy Development for Amyotrophic Lateral Sclerosis by Kalina Venkova-Hristova, Alexandar Christov, Zarine Kamaluddin, Peter Kobalka, Kenneth Hensley

“…Finally, this review will explore current trends in experimental therapeutics for ALS with emphasis on the emerging interest in axon guidance signaling pathways as novel targets for pharmacological support of neural cytoskeletal structure and function in order to slow ALS.…”
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The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Releva... by Kvido Smitka, Hana Papezova, Karel Vondra, Martin Hill, Vojtech Hainer, Jara Nedvidkova

“…The circulating autoantibodies can be purified and used as pharmacological tools in AN and BN. Further research is required to investigate the orexigenic/anorexigenic synthetic analogs and monoclonal antibodies for potential treatment of eating disorders in clinical practice.…”
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Type B non-Hodgkin lymphoma in a patient with acquired immunodeficiency virus with no detected viral load. Case report by Edwin Marcelo Miranda Solìs, Juan Fernando Orozco Herrera

“…For these reasons, we present the case of a 58-year-old patient, diagnosed with acquired immunodeficiency virus in the year 2000, who in the last ten years presented adequate clinical, virological, and pharmacological control. Suddenly and a few months ago, he began with symptoms related to a spinal cord compression syndrome at the lumbar level characterized by pain, functional impotence of the extremities and paresthesias. …”
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Effect of UV Irradiation on Interactions of α-Lipoic Acid with Free Radicals by Paweł Ramos, Piotr Pepliński, Barbara Pilawa

“…Application of electron paramagnetic resonance spectroscopy to characterize interactions of pharmacological substance with free radicals was confirmed.…”
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Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors by Gianluigi Zaza, Paola Tomei, Paolo Ria, Simona Granata, Luigino Boschiero, Antonio Lupo

“…Because of their specific pharmacological characteristics and their relative lack of nephrotoxicity, these inhibitors are valid option to calcineurine inhibitors (CNIs) for maintenance immunosuppression in renal transplant recipients with chronic allograft nephropathy. …”
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Effect of the Entorhinal Cortex on Ictal Discharges in Low-Mg2+-Induced Epileptic Hippocampal Slice Models by Ye-Jun Shi, Xin-Wei Gong, Hai-Qing Gong, Pei-Ji Liang, Pu-Ming Zhang, Qin-Chi Lu

“…The results showed that low-Mg2+ artificial cerebrospinal fluid induced interictal discharges in hippocampal slices, whereas, in combined EC-hippocampal slices the discharge pattern was alternated between interictal and ictal discharges, and ictal discharges initiated in the EC and propagated to the hippocampus. The pharmacological effect of the antiepileptic drug valproate (VPA) was tested. …”
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A Case Report of Mania and Psychosis Five Months after Traumatic Brain Injury Successfully Treated Using Olanzapine by Giordano F. Cittolin-Santos, Jesse C. Fredeen, Robert O. Cotes

“…There are few published pharmacologic trials for the treatment of acute mania following traumatic brain injury (TBI). …”
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Trauma-Induced Double-Seronegative Ocular Myasthenia Gravis: A Case Report by Mohammad Ali Khalid, Muhammad Jawad Awan, Ambreen Gull, Nida Hafeez, Bushra Ali, Fuad Ahmad Khan Niazi

“…History, examination and pharmacological (neostigmine test) tests were suggestive of ocular myasthenia gravis, however anti-acetylcholine receptor antibodies and anti-musk antibodies were negative. …”
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