Use of ECT in Major Vascular Neurocognitive Disorder with Treatment-Resistant Behavioral Disturbance following an Acute Stroke in a Young Patient by Kyle E. Rodenbach, Daniel Varon, Timothey Denko, Ryan Peterson, Carmen Andreescu

“…In most cases, first-line treatment includes pharmacologic intervention tailored to the most likely underlying syndrome. …”
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Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms by Rahul Singh, Ryan C. Turner, Linda Nguyen, Kartik Motwani, Michelle Swatek, Brandon P. Lucke-Wold

“…We discuss potential therapeutic and pharmacologic options as well as potential novel drug targets. …”
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PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors by Francesco Dituri, Antonio Mazzocca, Gianluigi Giannelli, Salvatore Antonaci

“…In addition, we discuss, from antitumor immunological point of view, the potential benefits and disadvantages arising from use of anticancer pharmacological agents targeting the PI3K pathway.…”
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Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease by Katherine Luo, Stewart Siyan Cao

“…Based on our increased understanding of ER stress in IBD, new pharmacological approaches can be developed to improve intestinal homeostasis by targeting ER protein-folding in the intestinal epithelial cells (IECs).…”
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Public interest in healthy lifestyle changes before and during the COVID-19 pandemic: Google Trends analysis by Seyma Trabzon, Pelin Ilhan, Havva Sert, Ali Sarıdas

“…Healthy lifestyle behaviors are accepted as non-pharmacological approaches in the management of diseases. …”
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Evaluation of Halogenated Coumarins for Antimosquito Properties by Venugopala K. Narayanaswamy, Raquel M. Gleiser, Kabange Kasumbwe, Bandar E. Aldhubiab, Mahesh V. Attimarad, Bharti Odhav

“…Natural coumarins and synthetic coumarin analogues are known for their several pharmacological properties, including being insecticidal. …”
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration by Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec

“…Equalizing GSK-3β activity in these mouse models by genetic or pharmacological interventions is able to rescue some of these abnormalities. …”
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Somatostatin Analogs in the Medical Management of Occult Bleeding of the Lower Digestive Tract by Julie Martin-Grace, Gianluca Tamagno

“…Despite the lack of double-blinded randomized placebo-control trials and despite the limitations of the available evidence in the literature, including small sample size, variable dosing, and administration routes, there is a consistent agreement in the literature that somatostatin analogs are a safe, well-tolerated, and effective therapeutic option for managing refractory or occult bleeding from the lower digestive tract, with particular reference to patients with angiodysplasia, where endoscopic or surgical management is either not feasible or unsuccessful and other pharmacological options are not preferred.…”
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The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review by Ambra Di Piazza, Federica Vernuccio, Massimo Costanzo, Laura Scopelliti, Dario Picone, Federico Midiri, Francesco Salvaggi, Francesco Cupido, Massimo Galia, Sergio Salerno, Antonio Lo Casto, Massimo Midiri, Giuseppe Lo Re, Roberto Lagalla

“…Gastrointestinal tract involvement in these patients may also due to both a direct action of antibodies against organs and pharmacological therapies. Dysphagia is one of the most important symptom, and it is caused by failure of the swallowing function and may lead to aspiration pneumonia, malnutrition, dehydration, weight loss, and airway obstruction. …”
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Study of the Use of Antinematode Drugs, Mebendazole and Pyrantel, in Galicia (Spain) from 2016 to 2020 by S. Vázquez- Prieto, A. Vaamonde, E. Paniagua

“…The main consequence of the excessive use of this drug compared to pyrantel may be the increased risk of the development of resistance and of therapeutic failure, as well as the consequent limitation of pharmacological options in the future.…”
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Recent Advances in Potential Clinical Application of Ghrelin in Obesity by Christine Delporte

“…Several classes of ghrelin-related pharmacological tools for the treatment of obesity have been or could be developed to modulate the identified molecular targets.…”
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Biological Characteristics and Medical Treatment of Breast Cancer in Young Women—A Featured Population: Results from the NORA Study by P. Pronzato, G. Mustacchi, A. De Matteis, F. Di Costanzo, E. Rulli, I. Floriani, M. E. Cazzaniga

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The Development of Publications on Catheter-Related Bladder Discomfort: A Bibliometric Analysis by Jiang W, Chen X, Peng Y, Zhai W, Zhang X, Zhou Y, Zhou R

“…Previous studies mainly focused on the pharmacological and pharmacological methods to CRBD. However, CRBD is not fully settled. …”
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Transcutaneous vagus nerve stimulation as a pain modulator in knee osteoarthritis: a randomized controlled clinical trial by Gehad Gamal Elsehrawy, Maha Emad Ibrahim, Nermeen Hassan A.moneim, Mohamed Ahmed Hefny, Nashwa Kamel El Shaarawy

“…Conclusion There is preliminary evidence to support the benefits of tVNS in OA, suggesting that neuromodulation can be used as an adjunct to existing pharmacological and non-pharmacological treatments. Trial registration The study was registered on ClinicalTrials.gov (NCT05387135) on 24/05/2022.…”
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Pilot study of extended-release lorcaserin for cocaine use disorder among men who have sex with men: A double-blind, placebo-controlled randomized trial. by Glenn-Milo Santos, Janet Ikeda, Phillip Coffin, John E Walker, Tim Matheson, Matthew McLaughlin, Jennifer Jain, Eric Vittinghoff, Steven L Batki

“…<h4>Conclusion</h4>We found that it is feasible, acceptable, and tolerable to conduct a placebo-controlled pharmacologic trial for MSM with CUD who are actively using cocaine. …”
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Tryptanthrin exerts anti-breast cancer effects both in vitro and in vivo through modulating the inflammatory tumor microenvironment by Zeng Qingfang, Luo Cairong, Cho Junlae, Lai Donna, Shen Xiangchun, Zhang Xiaoyan, Zhou Wei

“…Typically, this natural compound shows a variety of pharmacological activities such as antitumor, antibacterial, anti-inflammatory and antioxidant effects. …”
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Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease by Zhihao Qi, Quan Li, Shuhua Yang, Chun Fu, Burong Hu

“…Moreover, we found potential regulatory mechanisms of risk variants on IBD and potential pharmacological targets.…”
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Orofacial Pains by Vahid Rakhshan, Francesca A. Bianchi, Lucindo J. Quintans-Júnior, Aurelio A. Alonso

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Comprehensive Screening and Identification of Phillyrin Metabolites in Rats Based on UHPLC-Q-Exactive Mass Spectrometry Combined with Multi-Channel Data Mining by Beibei Ma, Jiameng Li, Tianyu Lou, Yaoyue Liang, Chenxiao Wang, Ruiji Li, Tingting Wang, Jinhui Liu, Yudong Guo, Zhibin Wang, Jing Wang

“…Phillyrin, a well-known bisepoxylignan, has been shown to have many critical pharmacological activities. In this study, a novel strategy for the extensive acquisition and use of data was established based on UHPLC-Q-Exactive mass spectrometry to analyze and identify the in vivo metabolites of phillyrin and to elucidate the in vivo metabolic pathways of phillyrin. …”
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Activity-Dependent NPAS4 Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System by José Fernando Maya-Vetencourt

“…This view has been recently challenged by experimental strategies based on the enhancement of environmental stimulation levels, genetic manipulations, and pharmacological treatments, which all have demonstrated that the adult brain retains a degree of plasticity that allows for a rewiring of neuronal circuitries over the entire life course. …”
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