Cyclooxygenase Inhibition in Sepsis: Is There Life after Death? by David M. Aronoff

“…In light of this, cyclooxygenase (COX) inhibiting pharmacological agents have been extensively studied for their capacity to ameliorate the aberrant physiological and immune responses during severe sepsis. …”
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New Targets of Neuroprotection in Ischemic Stroke by Marco Bacigaluppi, Dirk M. Hermann

“…Thus, our review will present an analysis of established and innovative strategies of neuroprotection and neurorestoration, highlighting both pharmacological and cell-based treatment concepts. In the last section of our paper, we will examine more closely how experimental data are presently translated to humans, with particular emphasis on the bioaccumulation and efficacy of drugs. …”
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Diagnosis of Dilated Cardiomyopathy: Patient Reaction and Adaptation—Case Study and Review of the Literature by Solomis Solomou, Maria Stavrou, Justin Marley

“…Various tools can be used to screen for depression in patients with heart failure. Both pharmacological and nonpharmacological options are available. …”
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Controversy About Management of Osteoarthritis with Disease-modifying Anti-rheumatic Drugs by CUI Hanshu, LIU Bin

“…As its pathophysiological mechanisms are not well understood, it is hard to identify the specific targets of OA and standardize its pharmacological treatments. Some scholars believe that synovial inflammation is the main factor of pain and progression of OA, so disease-modifying anti-rheumatic drugs (DMARDs) for inflammatory arthritis could be used to treat OA. …”
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Stretta Radiofrequency Treatment for GERD: A Safe and Effective Modality by Mark Franciosa, George Triadafilopoulos, Hiroshi Mashimo

“…Current treatments include lifestyle modifications, pharmacological therapies, surgical fundoplications, and, more recently, endoscopic procedures. …”
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YELLOW CAMELLIAS: A REVIEW OF CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES by Thi Diep Trinh

“…Chemical and biological studies have only been carried out on a few species, with the main focus on the Chinese species Camellia nitidissima, but have shown that the main active ingredients of these yellow camellia species include flavonoids, phenolic compounds, saponins, triterpenoids, phytosterols, essential oils, amino acids, and polysaccharides. Many pharmacological studies have proved that the total extracts, fractions, and isolated substances from yellow camellia species possess antioxidant, anticancer, hypolipidemic, hypoglycemic, antiallergic, hepatoprotective, neuroprotective, anxiolytic, and antidepressant activities. …”
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Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review by Geetanjali Rathore, Paul Larsen, Cristina Fernandez, Manish Parakh

“…Reassurance and education is the mainstay of therapy. Occasionally, pharmacologic intervention with iron, piracetam; atropine may be of benefit. …”
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Two Oral Midazolam Preparations in Pediatric Dental Patients: A Prospective Randomised Clinical Trial by Katayoun Salem, Shaqayegh Kamranzadeh, Maryam Kousha, Shahnaz Shaeghi, Fatemeh AbdollahGorgi

“…Pharmacological sedation is an alternative behavior management strategy in pediatric dentistry. …”
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The Role of the Microbiota in the Diabetic Peripheral Artery Disease by Federico Biscetti, Elisabetta Nardella, Andrea Leonardo Cecchini, Raffaele Landolfi, Andrea Flex

“…There is an urgency to develop the knowledge of modern medicine about the link between gut microbiota and its host’s metabolic pathways, and it would be useful to understand and justify the interindividual diversity of clinical disease presentation of diabetic vascular complication even if an optimization of pharmacological treatment has been made or in the case of young patients where hypertension, dyslipidemia, and diabetes are not able to justify a very quick progress of atherosclerotic process. …”
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Perbedaan Pengaruh Teknik Relaksasi Nafas Dalam Dan Kompres Hangat Dalam Menurunkan Dismenore Pada Remaja SMA Negeri 3 Padang by Vetty Priscilla, Dwi Christina Rahayu Ningrum, Lili Fajria

“… Some women experience dysmenorrhoea in each menstrual cycle, the intensity of pain that is felt even to severe and interfere with the activity. One non-pharmacological therapies that can be done to reduce dysmenorrhea relaxation techniques and breathing in the warm compresses. …”
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Dendritic Cell-Based Approaches for Therapeutic Immune Regulation in Solid-Organ Transplantation by Giuseppe Vassalli

“…DCs can be treated with pharmacological agents before injection, which may attenuate their maturation in vivo. …”
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Literature Review: Pericranial Nerve Blocks for Chronic Migraines by Stephanie Wahab, Saurabh Kataria, Parker Woolley, Naanama O’Hene, Chima Odinkemere, Rosa Kim, Ivan Urits, Alan D. Kaye, Jamal Hasoon, Cyrus Yazdi, Christopher L Robinson

“…Current methods of migraine treatment include lifestyle changes, pharmacologic, and minimally invasive techniques such as peripheral nerve stimulation (PNS) and pericranial nerve blocks (PNB)…”
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Up-to-date methods of stomach functions investigation and their diagnostic potentials by Ya. S. Tsimmerman

“…Advantages of modern multichannel рН-meters, potential of acquiring of the supplemental information by original methods of intragastric рН-grams analysis with application of various pharmacological and stimulaion tests are analyzed. Methods of studying of gastric juice proteolytic activity are compared. …”
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UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam by Hong Ngoc Pham, Chieu An Tran, Thi Diep Trinh, Ngoc Lan Nguyen Thi, Huynh Nhu Tran Phan, Van Nhan Le, Ngoc Hung Le, Van Trung Phung

“…Hedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. …”
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ACSL4 promotes the formation of the proliferative subtype in hepatoblastoma by Wei Dang, Qin Li, Xiaoying Wang

“…ACSL4 emerged as a critical biomarker of this proliferative subtype, driving HB cell proliferation both in vitro and in vivo. Furthermore, pharmacological inhibition of ACSL4 using abemaciclib significantly suppressed tumor growth in xenograft models. …”
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Cardiopulmonary bypass associated acute kidney injury: better understanding and better prevention by Xutao Yang, Li Zhu, Hong Pan, Yi Yang

“…Finally, we explore current interventions aimed at preventing and attenuating renal impairment related to CPB, and presenting these measures from three perspectives: (1) avoiding CPB to eliminate the fundamental impact on renal function; (2) optimizing CPB by adjusting equipment parameters, optimizing surgical procedures, or using improved materials to mitigate kidney damage; (3) employing pharmacological or interventional measures targeting pathogenic factors.…”
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Electrochemical Behavior of Quinoxalin-2-one Derivatives at Mercury Electrodes and Its Analytical Use by Milan Zimpl, Jana Skopalova, David Jirovsky, Petr Bartak, Tomas Navratil, Jana Sedonikova, Milan Kotoucek

“…Derivatives of quinoxalin-2-one are interesting compounds with potential pharmacological activity. From this point of view, understanding of their electrochemical behavior is of great importance. …”
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Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma by Girolamo Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Cecilia Calabrese, Rosa Terracciano, Rosario Maselli

“…The recent advances in the knowledge of the cellular and molecular mechanisms underlying asthmatic inflammation are contributing to the identification of novel therapeutic targets, potentially suitable for the implementation of future improvements in antiasthma pharmacologic treatments.…”
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Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects by Boyun Gou, Guoqing Chen, Shicong Huang, Na Ning, Qian Gu, Shuai Duan, Yuhua Du, Yi Nan, Ling Yuan

“…In addition, jujube has received much attention around the world for its excellent pharmacological effects and food value. This article reviews the anticancer effects of a fruit, food, and drug, jujube, which have been shown in current studies, and analyzes its therapeutic mechanism, active ingredients, extraction and isolation methods, as well as its synergistic and attenuation performance in cancer. …”
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Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection by Priscilla Aparecida Tartari Pereira, Bruno Caetano Trindade, Adriana Secatto, Roberto Nicolete, Camila Peres-Buzalaf, Simone Gusmão Ramos, Ruxana Sadikot, Claudia da Silva Bitencourt, Lúcia Helena Faccioli

“…Therefore, using a pharmacological inhibitor, celecoxib, we investigated the role of prostaglandins in host defense against Histoplasma capsulatum infection in C57BL/6 mice. …”
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