Exercise and Physical Activity in the Therapy of Substance Use Disorders by Elisabeth Zschucke, Andreas Heinz, Andreas Ströhle

“…Exercise and physical activity are constantly gaining attention as adjuvant treatment for substance use disorders, supplementing classical pharmacological and psychotherapeutic approaches. The present work reviews studies addressing the therapeutic effects of exercise in alcohol abuse/dependence, nicotine abuse/dependence, and illicit drug abuse/dependence. …”
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Molecular pathogenesis of Cryptosporidium and advancements in therapeutic interventions by Lu Yilong, Zhang Xiaoning, Guan Zhiyu, Ji Rui, Peng Fujun, Zhao Chunzhen, Gao Wei, Gao Feng

“…Ongoing research is focused on understanding the molecular pathogenesis of Cryptosporidium and developing pharmacological treatments. In this review, we examine the signaling pathways activated by Cryptosporidium infection within the host and their role in protecting host epithelial cells. …”
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Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis by Manuela Di Franco, Bruno Lucchino, Fabrizio Conti, Guido Valesini, Francesca Romana Spinelli

“…The purpose of this review is to describe the main causes of increased methylarginine levels in RA, their implication in accelerated atherosclerosis, the possible role as biomarkers of cardiovascular risk, and finally the available data on current pharmacological treatment.…”
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CATHINONES AND VIAGRA IN CHEMSEX: AN AUTOETHNOGRAPHY OF TOUCH, MASCULINITIES AND AESTHETICS by Jorge Humberto Lucero Díaz

“…The results reveal that chemsex practices are deeply relational, influenced by both pharmacological effects and aesthetic norms. The study concludes that chemsex constitutes a space of complex cultural transformation, where new forms of relationship, pleasure, and gender expression are challenged and redefined.…”
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Review on mechanisms and structure-activity relationship of hypoglycemic effects of polysaccharides from natural resources by Xiaolong Ji, Jianhang Guo, Tengzheng Cao, Tingting Zhang, Yanqi Liu, Yizhe Yan

“…We have summarized recent research of natural polysaccharides with hypoglycemic activities, focusing on different pharmacological mechanisms in various cell and animal models. …”
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Macular Hole of the Left Eye in a 41-year-old Patient with Retinitis pigmentosa. A Case Report by Bożena Kmak, Tomasz Siewierski, Anna Szot, Sebastian Sirek

“…Retinitis pigmentosa is a genetic disorder, therefore genetic counseling and screening of family members for retinitis pigmentosa is important. The specific pharmacological treatment is still unknown. In severe cases posterior vitrectomy is performed as a basic method of curing macular holes.…”
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A bioabsorbable mechanoelectric fiber as electrical stimulation suture by Zhouquan Sun, Yuefan Jin, Jiabei Luo, Linpeng Li, Yue Ding, Yu Luo, Yan Qi, Yaogang Li, Qinghong Zhang, Kerui Li, Haibo Shi, Shankai Yin, Hongzhi Wang, Hui Wang, Chengyi Hou

“…Electrical stimulation is a non-pharmacological therapy that promotes wound healing. In this context, we designed a passive and biodegradable mechanoelectric suture. …”
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Development of a Multimodal Analgesia Protocol for Perioperative Acute Pain Management for Lower Limb Amputation by Roberta De Jong, Alexander J. Shysh

“…Multimodal analgesia may include pharmacological components such as regional anesthesia, opioid and nonopioid systemic analgesics, nonsteroidal anti-inflammatories, and a variety of adjuvant agents. …”
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Multiple Approaches to Investigate the Transport and Activity-Dependent Release of BDNF and Their Application in Neurogenetic Disorders by David Hartmann, Jana Drummond, Erik Handberg, Sharday Ewell, Lucas Pozzo-Miller

“…Studies utilizing genetic and pharmacological manipulations in rodent models and neuronal cultures have revealed myriad roles of brain-derived neurotrophic factor (BDNF). …”
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Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion by M. J. Levy, I. Robertson, T. A. Howlett

“…We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. …”
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Remission of Cognitive Deficits in Parkinson’s Disease: Recovery from a Nonamnestic Mild Cognitive Impairment or Psychiatric Symptoms Remission? by Jonas Jardim de Paula, Marco Túlio Gualberto Cintra, Débora Marques Miranda, Maria Aparecida Camargos Bicalho, Edgar Nunes Moares, Leandro Fernandes Malloy-Diniz

“…We discuss the possible causes for the remission, focusing on the treatment of medical conditions such as a major depressive episode and vitamin B12 deficiency, in addition to the change of pharmacological treatment. In a third assessment, cognitive performance remained normal. …”
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Gastrointestinal Motility Disorders and Their Clinical Implications in Cirrhosis by Eleni Theocharidou, Ameet Dhar, David Patch

“…Enhanced colonic motility is usually associated with the use of lactulose. Pharmacological interventions aiming to alter gastrointestinal motility in cirrhosis could potentially have a beneficial effect reducing the risk of hepatic decompensation and improving prognosis.…”
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GABA Metabolism and Transport: Effects on Synaptic Efficacy by Fabian C. Roth, Andreas Draguhn

“…We will discuss the functional impact of such regulations on neuronal network patterns and, finally, point towards pharmacological approaches targeting these processes.…”
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Behavioural and Cognitive-Behavioural Treatments of Parasomnias by Andrea Galbiati, Fabrizio Rinaldi, Enrico Giora, Luigi Ferini-Strambi, Sara Marelli

“…Parasomnias are unpleasant or undesirable behaviours or experiences that occur predominantly during or within close proximity to sleep. Pharmacological treatments of parasomnias are available, but their efficacy is established only for few disorders. …”
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The Use of Technology in the Management of Orthodontic Treatment-Related Pain by Anand Marya, Adith Venugopal

“…Over the years, several treatment modalities have been utilized for relief from orthodontic pain, and these include mechanical, behavior modification, and pharmacological methods. However, in the last decade, there are several newer methods employing the use of technology that have come up and are being used for alleviating pain. …”
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Smoking and Health: A Physician Responsibility—A Statement of the Joint Committee on Smoking and Health by Joint Committee on Smoking and Health

“…Physicians should play an active role in control of smoking by ensuring that counselling and pharmacological therapy be available for the individual smoker. …”
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Revisiting Apathy in Alzheimer’s Disease: From Conceptualization to Therapeutic Approaches by Antonio L. Teixeira, Mitzi M. Gonzales, Leonardo Cruz de Souza, Sara L. Weisenbach

“…Given its complex pathophysiology, including distinct substrates for different apathy dimensions (affective, cognitive, and behavioral), it is unlikely that a single pharmacological or nonpharmacological strategy will be effective for all cases of apathy in AD. …”
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Development, Characterization, and Pharmacodynamic Evaluation of Hydrochlorothiazide Loaded Self-Nanoemulsifying Drug Delivery Systems by Pankajkumar S. Yadav, Ekta Yadav, Amita Verma, Saima Amin

“…In vivo pharmacodynamic evaluation in Wistar rats showed considerable increase in pharmacological effect of HCT by SNEDDS formulation as compared with plain HCT.…”
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Mitochondrial Dysfunction and Diabetic Nephropathy: Nontraditional Therapeutic Opportunities by Ping Na Zhang, Meng Qi Zhou, Jing Guo, Hui Juan Zheng, Jingyi Tang, Chao Zhang, Yu Ning Liu, Wei Jing Liu, Yao Xian Wang

“…Growing evidence shows that persistent mitochondrial dysfunction contributes to the progression of renal diseases, including DN, as it alters mitochondrial homeostasis and, in turn, affects normal kidney function. Pharmacological regulation of mitochondrial networking is a promising therapeutic strategy for preventing and restoring renal function in DN. …”
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Stress Effects on Multiple Memory System Interactions by Deborah Ness, Pasquale Calabrese

“…Extensive behavioural, pharmacological, and neurological research reports stress effects on mammalian memory processes. …”
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