Factors Contributing to the Utilization of Adult Mental Health Services in Children and Adolescents Diagnosed with Hyperkinetic Disorder by Hilario Blasco-Fontecilla, Juan J. Carballo, Rebeca Garcia-Nieto, Jorge Lopez-Castroman, Analucia A. Alegria, Ignacio Basurte-Villamor, Juncal Sevilla-Vicente, Rocio Navarro-Jimenez, Teresa Legido-Gil, Consuelo Morant-Ginestar, Miguel Angel Jimenez-Arriero, Jeronimo Saiz-Ruiz, Enrique Baca-Garcia

“…Older age of first diagnosis, female gender, psychiatric comorbidity, and pharmacological treatment at CAMHS are markers of risk for the transition from CAMHS to AMHS in patients with hyperkinetic disorder diagnosed at CAMHS.…”
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IBS as a diverse disease. A comprehensive review by Adrianna Dylik, Weronika Gryczyńska, Mikołaj Musiał, Łukasz Krawczak, Hanna Gulaczyk, Jan Spychalski, Mikołaj Kaczmarek, Wiktoria Grochowska, Maria Spychalska

“…The primary objective is to highlight contemporary approaches to patient care, revisiting both pharmacological and non-pharmacological treatment strategies.                                                                                                                                …”
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Amelioration of premature aging in Werner syndrome stem cells by targeting SHIP/AKT pathway by Hei-Yin Tam, Jiaxing Liu, Tsz-Ching Yiu, Adrian On-Wah Leung, Chang Li, Shen Gu, Owen Rennert, Boxian Huang, Hoi-Hung Cheung

“…Results In this study, we profiled the signaling pathways altered in WRN-deficient MSC and applied pharmacological method to activate the AKT signaling in these cells and examined their cellular phenotype related to aging. …”
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The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents by Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Efthymios Deligeoroglou, Zoe Iliodromiti

“…Many of these oxytocin receptor antagonists are used only as pharmacological tools, while others have tocolytic action. …”
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Dengue Virus Infection Causes the Activation of Distinct NF-κB Pathways for Inducible Nitric Oxide Synthase and TNF-α Expression in RAW264.7 Cells by Yi-Lin Cheng, Yee-Shin Lin, Chia-Ling Chen, Shu-Wen Wan, Yi-Dan Ou, Chia-Yi Yu, Tsung-Ting Tsai, Po-Chun Tseng, Chiou-Feng Lin

“…NF-κB is known to be activated by DENV infection. Pharmacologically inhibiting NF-κB activation abolishes iNOS/NO biosynthesis and TNF-α production. …”
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Clinical Aspects and Management of Levodopa-Induced Dyskinesia by Nicola Tambasco, Simone Simoni, Erica Marsili, Elisa Sacchini, Donatella Murasecco, Gabriela Cardaioli, Aroldo Rossi, Paolo Calabresi

“…Dopamine agonists with different pharmacological profile are available. Our paper was aimed to analyse the clinical impact and the management of dyskinesias with dopamine agonists.…”
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Biosynthesis of Silver Nanoparticles and Its Applications by M. Jannathul Firdhouse, P. Lalitha

“…Biogenic syntheses of silver nanoparticles using plants and their pharmacological and other potential applications are gaining momentum owing to its assured rewards. …”
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Administration of PDE4 Inhibitors Suppressed the Pannus-Like Inflammation by Inhibition of Cytokine Production by Macrophages and Synovial Fibroblast Proliferation by Katsuya Kobayashi, Toshio Suda, Haruhiko Manabe, Ichiro Miki

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Potentiation of Doxorubicin Cytotoxicity Utilizing Clarithromycin Loaded-PEGylated Liposomes by Islam Alfreahat MS, Hamdi Nsairat PhD, Ibrahim Deeb Aldeeb PhD, Ali Al-Samydai PhD, Walhan Alshaer PhD

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HUMAN GENES CONTROLLING FEEDING BEHAVIOR OR BODY MASS AND THEIR FUNCTIONAL AND GENOMIC CHARACTERISTICS: A REVIEW by E. V. Ignatieva, D. A. Afonnikov, E. I. Rogaev, N. A. Kolchanov

“…The compilation can be used in genotyping for pathology risk estimation and for designing new pharmacological approaches for treatment of human obesity.…”
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Fighting Alzheimer’s with Movement: The Role of Physical Activity in Disease Management by Agnieszka Kosińska, Magdalena Balwierz, Karolina Kalinowska, Urszula Świrk, Jan Karczmarz, Joanna Orzechowska, Marika Gutowska, Michał Orzechowski, Aleksandra Paprocka, Paulina Fijałek

“…This highlights the effectiveness of physical activity as a valuable, non-pharmacological approach to managing Alzheimer's. …”
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PGC-1α activation to enhance macrophage immune function in mycobacterial infections. by Joel R Frandsen, Zhihong Yuan, Brahmchetna Bedi, Zohra Prasla, Seoung-Ryoung Choi, Prabagaran Narayanasamy, Ruxana T Sadikot

“…Importantly, rescuing expression of PGC-1α and TFAM using pharmacologic approaches restored macrophage immune function. …”
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Noninsulin Antidiabetic Drugs for Patients with Type 2 Diabetes Mellitus: Are We Respecting Their Contraindications? by Irene Ruiz-Tamayo, Josep Franch-Nadal, Manel Mata-Cases, Dídac Mauricio, Xavier Cos, Antonio Rodriguez-Poncelas, Joan Barrot, Gabriel Coll-de-Tuero, Xavier Mundet-Tudurí

“…Electronic medical records were retrieved from all T2DM subjects who attended primary care centers pertaining to the Catalan Health Institute in Catalonia in 2013 and were pharmacologically treated with any NIAD alone or in combination. …”
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Benson’s spiritual relaxation and lavender aromatherapy toward anxiety, sleep quality, and blood pressure by Eppy Setiyowati, Umdatus Soleha, Mulyadi Mulyadi, Muhammad Basuni

“…Therefore, in addition to pharmacological treatment, non-pharmacological therapy is essential to reduce anxiety, lower blood pressure, and improve sleep quality in hypertensive patients. …”
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Sideroxylon inerme L. (Sapotaceae): A narrative of its uses as ethnoveterinary medicine and other medicinal applications by Alfred Maroyi

“…The phytochemical assessment of the taxon showed that it contains flavonoids, alkaloids, phenols, saponins, sterols, tannins, terpenes, terpenoids, and triterpenoids. Pharmacological evaluations of the taxon revealed that the crude extracts and phytochemical compounds isolated from the taxon are characterized by antifungal, antibacterial, antioxidant, anti-proliferative, and tyrosinase inhibitory activities. …”
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Perbedaan Pengaruh Terapi Napas Dalam dan Terapi Relaksasi Otot Progresif terhadap Penurunan Tekanan Darah Lansia Hipertensi di Posyandu Lansia Kelurahan Surau Gadang Kecamatan... by Melda Yulinda, Lili Fajria

“… Hypertension is a disease that affects many elderly. Non-pharmacological management is recommended to avoid the effects of pharmacological treatment in the elderly. …”
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Linezolid and serotonin syndrome by Haytham A. Wali

“…Assessments of the pharmacological mechanisms, large-scale clinical trials, and cohort studies are essential to elucidate risk factors and outcomes. …”
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Comparative analysis of physicochemical properties, ginsenosides content and α-amylase inhibitory effects in white ginseng and red ginseng by Huairui Wang, Yao Cheng, Xue Zhang, Yingping Wang, Hui Zhao

“…Quantitative analysis of multi-components by a single-marker (QAMS) method and anti-α-amylase activity test were used to assess variations of chemical ingredients and pharmacological activity between white and red ginseng. …”
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Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9 by Cancan Zhou, Zhengyuan Feng, Weikun Qian, Zeen Zhu, Ruiqi Cao, Qiqi Wang, Wunai Zhang, Rujuan Liu, Shuai Wu, Jie Hao, Zheng Wang, Qingyong Ma, Zheng Wu, Xuqi Li

“…In vitro, either knockdown or pharmacological inhibition of SREBP1 suppressed tumor proliferation but SREBP1 overexpression promoted tumor proliferation. …”
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NREM and REM sleep parasomnias: clinical cases and literature review by K. Teišerskytė, I. Čelpačenko, E. Pajėdienė

“…NREM parasomnias are often benign, self-limited, or resolved with non-pharmacological treatment, while REM sleep behaviour disorder (example of REM parasomnias) is much more likely to occur in adult age and is associated with neurodegenerative diseases. …”
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