Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes: A Prespecified Analysis of the Benedict Trial by Piero Ruggenenti, Ilian Iliev, Marco Filipponi, Stefano Tadini, Annalisa Perna, Maria Ganeva, Bogdan Ene-Iordache, Paolo Cravedi, Roberto Trevisan, Antonio Bossi, Giuseppe Remuzzi

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Nicotine Replacement Combined with a Novel Compound (ProBAN) for Smoking Cessation: A Pilot Study by Richard Leigh, Norman M Viner, Gerard Cox, Jeffrey W Balon, Douglas MC Wilson, Denise O’Shaughnessy, Corinne Walker, Gerry Brosky, Malcolm R Sears

“…BACKGROUND: Smoking cessation rates with available pharmacological therapies remain suboptimal. Anecdotal observations with a combination of sublingual pralidoxime and ipratropium (ProBAN) suggested that these agents in combination with nicotine gum improved quit rates.…”
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Evidence-Based Guideline for Neuropathic Pain Interventional Treatments: Spinal Cord Stimulation, Intravenous Infusions, Epidural Injections and Nerve Blocks by Angela Mailis, Paul Taenzer

“…BACKGROUND: The Special Interest Group of the Canadian Pain Society has produced consensus-based guidelines for the pharmacological management of neuropathic pain. The society aimed to generate an additional guideline for other forms of neuropathic pain treatments.…”
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Effects of Unilateral Nephrectomy on Renal Function in Male Spontaneously Diabetic Torii Fatty Rats: A Novel Obese Type 2 Diabetic Model by Yoshiaki Katsuda, Yusuke Kemmochi, Mimi Maki, Ryuhei Sano, Yasufumi Toriniwa, Yukihito Ishii, Katsuhiro Miyajima, Kochi Kakimoto, Takeshi Ohta

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Anti-Inflammatory and Antioxidant Properties of a New Mixture of Vitamin C, Collagen Peptides, Resveratrol, and Astaxanthin in Tenocytes: Molecular Basis for Future Applications in... by Monica Marzagalli, Stefania Battaglia, Michela Raimondi, Fabrizio Fontana, Marco Cozzi, Francesca R. Ranieri, Roberto Sacchi, Valeria Curti, Patrizia Limonta

“…Patients suffering from this pathology frequently experience pain, swelling, stiffness, and muscle weakness. Current pharmacological interventions are based on nonsteroidal anti-inflammatory drugs; however, the effectiveness of these strategies remains ambiguous. …”
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Research Progress in Natural Sources, Biosynthesis and Metabolism Regulation of Rutin in Plant-Derived Food Materials by ZHOU Ting, WANG Haige, ZHANG Jixing, BAO Yingcai, YU Yongli, CHANG Jie

“…It possesses various pharmacological and physiological activities, including antioxidant, anti-aging, anti-inflammatory, anti-diabetic, and anti-cancer properties. …”
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Terpenoids and Their Biological Activities from Cinnamomum: A Review by Meiting Wu, Lin Ni, Haixiao Lu, Huiyou Xu, Shuangquan Zou, Xiaoxing Zou

“…Hence, further studies on the potential pharmacological effects need to be conducted in the future.…”
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Switching to Aripiprazole as a Strategy for Weight Reduction: A Meta-Analysis in Patients Suffering from Schizophrenia by Yoram Barak, Dov Aizenberg

“…Weight gain is one of the major drawbacks associated with the pharmacological treatment of schizophrenia. Existing strategies for the prevention and treatment of obesity amongst these patients are disappointing. …”
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Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent by Sharifah Nurul Akilah Syed Mohamad, Alfi Khatib, Siti Zaiton Mat Soád, Qamar Uddin Ahmed, Zalikha Ibrahim

“…The focus is on the species’ ethnomedicinal applications, their potential as an antidiabetic agent, the pharmacologically active antidiabetic compounds possessed, and their toxicological profiles. …”
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To Use or Not to Use Metformin in Cerebral Ischemia: A Review of the Application of Metformin in Stroke Rodents by Isaac Arbeláez-Quintero, Mauricio Palacios

“…AMPK activation has been described as one of the pharmacological mechanisms that explain the action of metformin and that lead to neuroprotective effects. …”
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Potential Neuroprotective Effect of the Endocannabinoid System on Parkinson’s Disease by María Fernanda Urmeneta-Ortíz, Aldo Rafael Tejeda-Martínez, Orfil González-Reynoso, Mario Eduardo Flores-Soto

“…Unfortunately, conventional pharmacological treatments fail to halt disease progression; therefore, new therapeutic strategies are needed, and currently, some are being investigated. …”
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Chronic pain in a family doctor practice – meaning, assessment, and therapeutic options by Dominika Prokop, Mikołaj Borek, Jan Baran, Dawid Rowiński, Oliwia Sikora, Katarzyna Chamera-Cyrek, Aneta Podczerwińska, Clara Kuzminski

“…According to the recommendations of the International Association for the Study of Pain, patients with chronic pain should be treated interdisciplinarily, incorporating not only pharmacological treatments but also psychological, rehabilitative, and other non-pharmacological methods. …”
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Isoliquiritigenin Inhibits Atherosclerosis by Blocking TRPC5 Channel Expression by Jie Qi, Jianguo Cui, Baobin Mi, Xiaohong Yan, Wenwen Xu, Hui Ma, Qingtan Zhang, Fang Xu

“…In conclusion, our findings provide novel insight into the pharmacological effects of ISL on atherosclerosis and suggest that ISL is beneficial for cardiovascular protection.…”
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Anti-Inflammatory Activity of Compounds Isolated from Plants by R.M. Perez G.

“…They have been classified in appropriate chemical groups and data are reported on their pharmacological effects, mechanisms of action, and other properties.…”
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Protective Role of the ACE2/Ang-(1–9) Axis in Cardiovascular Remodeling by María Paz Ocaranza, Jorge E. Jalil

“…Despite reduction in cardiovascular (CV) events and end-organ damage with the current pharmacologic strategies, CV disease remains the primary cause of death in the world. …”
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FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and Pathophysiology by Yusuke Murata, Morichika Konishi, Nobuyuki Itoh

“…These findings suggest the pharmacological effects to be distinct from the physiological roles. …”
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The Critical Management of Spinal Cord Injury: A Narrative Review by Emilio Moreno-González, Antonio Ibarra

“…This review includes 50 publications selected based on specific criteria to gather evidence on the current management of SCI in acute settings. Pharmacological agents have been studied for their neuroprotective properties, offering hope for improved neurological outcomes. …”
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Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy by Yuan-qiao Xu, Yanjiao Chen, Jia-xin Xing, Jun Yao

“…Abstract Enriched environment (EE), as a non-pharmacological intervention, has garnered considerable attention for its potential to ameliorate neurodegenerative diseases (NDs). …”
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Quantitative Determination of Flavonoids and Chlorogenic Acid in the Leaves of Arbutus unedo L. Using Thin Layer Chromatography by Željan Maleš, Darija Šarić, Mirza Bojić

“…The plant species Arbutus unedo shows numerous beneficial pharmacological effects (antiseptic, antidiabetic, antidiarrheal, astringent, depurative, antioxidant, antihypertensive, antithrombotic, and anti-inflammatory). …”
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Effectiveness of an Inpatient Movement Disorders Program for Patients with Atypical Parkinsonism by Anna D. Hohler, Jyeming M. Tsao, Douglas I. Katz, T. Joy DiPiero, Christina L. Hehl, Alissa Leonard, Valerie Allen, Maura Gardner, Heidi Phenix, Marie Saint-Hilaire, Terry Ellis

“…This paper investigated the effectiveness of an inpatient movement disorders program for patients with atypical parkinsonism, who typically respond poorly to pharmacologic intervention and are challenging to rehabilitate as outpatients. …”
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