Phosphodiesterase 4 inhibition as a novel treatment for stroke by Jiahong Zhong, Xihui Yu, Zhuomiao Lin

“…It may potentially outweigh the benefits and fail to ameliorate the cerebral tissue damage following ischemia. Therefore, pharmacological intervention assumes paramount importance. …”
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Technical aspects of neuraxial analgesia during labor and maternity care: an updated overview by Antonio Coviello, Carmine Iacovazzo, Maria Grazia Frigo, Marilena Ianniello, Dario Cirillo, Giuseppe Tierno, Andrea Uriel de Siena, Pasquale Buonanno, Giuseppe Servillo

“…After bibliographic research since 2018 to 2023, many randomized controlled trials, literature reviews, systematic reviews, and metanalysis were evaluated to create this brief overview. The following pharmacological and non-pharmacological approaches were assessed: spinal techniques, such as epidural analgesia (EA), combined spinal-epidural (CSE), dural puncture epidural (DPE), and continuous spinal anesthesia (CSA); pharmacological administration of nitrous oxide (N2O) and systemic opioids (morphine, fentanyl, and pethidine); as the third one transcutaneous electric nerve stimulation (TENS), acupressure/acupuncture, aromatherapy, and breathing exercises. …”
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Turnour necrosis factor stimulates endothelin-1 gene expression in cultured bovine endothelial cells by Silvia Orisio, Marina Morigi, Carla Zoja, Norberto Perico, Giuseppe Remuzzi

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Liquid Chromatography-Tandem Mass Spectrometry Analysis of Perfluorooctane Sulfonate and Perfluorooctanoic Acid in Fish Fillet Samples by Viviana Paiano, Elena Fattore, Andrea Carrà, Caterina Generoso, Roberto Fanelli, Renzo Bagnati

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Pharmacokinetics of Hyperthermic Intrathoracic Chemotherapy following Pleurectomy and Decortication by Paul H. Sugarbaker, O. Anthony Stuart, Christopher Eger

“…When the clearance of chemotherapy from the thoracic cavity was compared to clearance from the abdomen and pelvis, there was a considerably more rapid clearance from the abdomen as compared to the thorax. The pharmacologic study of intrapleural chemotherapy in these patients provides a strong pharmacologic rationale for regional chemotherapy in this group of patients.…”
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Emergency Abdominal Aortic Aneurysm Repair in a Patient with Failing Heart: Axillofemoral Bypass Using a Centrifugal Pump Combined with Levosimendan for Inotropic Support by Pavel Michalek, Pavel Sebesta, Michael Stern

“…The procedure was performed with the help of both mechanical and pharmacological circulatory support. Distal perfusion was provided by an axillofemoral bypass with a centrifugal pump, with dobutamine and levosimendan administered as pharmacological inotropic support. …”
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JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Improves Hyperglycemia and Dyslipidemia Independent of Suppression of Food Intake in Diab... by Shohei Sakata, Makoto Ito, Yasuko Mera, Tomohiko Sasase, Hiromi Yamamoto, Makoto Kakutani, Takeshi Ohta

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Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity by Chiara Macchi, Andrea Giachi, Isabella Fichtner, Silvia Pedretti, Piercarlo Sarzi-Puttini, Nico Mitro, Alberto Corsini, Massimiliano Ruscica, Roberta Gualtierotti

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Botanicals as Modulators of Neuroplasticity: Focus on BDNF by Enrico Sangiovanni, Paola Brivio, Mario Dell’Agli, Francesca Calabrese

“…Further clinical studies are mandatory to confirm botanicals as preventive agents or as useful adjuvant to the pharmacological treatment.…”
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THE ROLE OF ACUPUNCTURE THERAPY TO OVERCOME ONE-SIDE HEAD PAIN (MIGRAINE) by Mut Mainnah, Wurlina Wurlina, Maya Septriana

“…Migraine can interfere with patient activities, so that it can reduce productivity and result in an economic burden to the family and reduce the patient's quality of life. To handle it, pharmacological and non-pharmacological therapies can be used. …”
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Perpaduan Isometric Exercise dan Latihan Pernafasan Yoga Terhadap Penurunan Tekanan Darah pada Pasien Hipertensi di Desa Mojojajar Wilayah Kerja Puskesmas Kedungsari Kabupaten Mojo... by Dinda Risma Putri Anjarsari, Abdul Hanan, Esti Widiani

“…One of the non-pharmacological treatments that can be done to lower blood pressure is to increase the patient's physical activity, such as Isometric Exercise and Yoga breathing exercises. …”
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Biological Aspects of Emerging Benzothiazoles: A Short Review by Ruhi Ali, Nadeem Siddiqui

“…In recent years heterocyclic compounds analogues and derivatives have attracted wide attention due to their useful biological and pharmacological properties. Benzothiazole is among the usually occurring heterocyclic nuclei in many marine as well as natural plant products. …”
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A review of traditional Chinese medicine intervention methods for depression among college students by Xiyong Yao, Chen Xu, Linlin Yang, Ailin Wu, Lin Xiong, Lin Xiong

“…Traditional Chinese Medicine (TCM) boasts a long history in the prevention and treatment of psychological and emotional disorders, encompassing non-pharmacological therapies (such as TCM health exercises, Tai Chi, Wu Qin Xi, Ba Duan Jin, acupuncture, etc.) and pharmacological treatments. …”
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Design and synthesis of amino-substituted N-arylpiperidinyl-based inhibitors of the (immuno)proteasome by Gobec Martina, Obreza Aleš, Jukič Marko, Baumgartner Ana, Mihelčič Nja, Potočnik Špela, Virant Julija, Mlinarič Irena, Stanislav Raščan, Sosič Gobec Izidor

“…The constitutive proteasome and the immunoproteasome represent validated targets for pharmacological intervention in the context of various diseases, such as cancer, inflammation, and autoimmune diseases. …”
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Seizure following the Use of the COX-2 Inhibitor Etoricoxib by Valentina Arnao, Marianna Riolo, Brigida Fierro, Paolo Aridon

“…Conclusion. Knowing the pharmacological history of a patient is important for understanding the clinical presentation and selecting appropriate treatment. …”
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Cancer, Natural Products and Nanodrug Delivery Systems by Yong Sze Ong, Loh Teng-Hern Tan

“…NDDS improves the in vivo pharmacological and therapeutic properties of the poorly soluble drugs by dissolving, encapsulating, absorbing and/or attaching the drugs with the matrices of the nanoparticles. …”
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Pharmacogenetic markers of colorectal cancer treatment. New approaches for cytostatic drugs efficacy estimation by N. B. Zakharzhevskaya, N. A. Kulemin, Ye. A. Babikova, Ye. B. Khomyakova, E. V. Generozov

“…The success of CRC chemotherapy depends significantly on the individual genetic features of the patient influencing both efficacy of pharmacological effects, and degree of side effects severity. …”
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Hydroxyurea Treatment for Sickle Cell Disease by Martin H. Steinberg

“…It is a promising beginning for pharmacologic therapy of sickle cell disease. Still, its effects are inconsistent, trials in infants and children are ongoing, and its ultimate value — and peril — when started early in life are still unknown.…”
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Comprehensive Approach to Cancer Pain in Pediatric Patients by Alexis Ramón Pineda González, Grettel Águila Calero, Anaelys Acosta Hernández, Marilyn Ramírez Méndez

“…All through a comprehensive approach that includes both pharmacological and non-pharmacological measures.…”
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Downbeat Nystagmus Induced by Sedation in Lasik by Miguel Paciuc-Beja, Gerardo Mendieta

“…Nystagmus can be pharmacologically induced and can be a hazard to refractive surgery.…”
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