Osteopontin Expression in the Brain Triggers Localized Inflammation and Cell Death When Immune Cells Are Activated by Pertussis Toxin by Maria Cecilia Garibaldi Marcondes, Ryan Ojakian, Nikki Bortell, Claudia Flynn, Bruno Conti, Howard S. Fox

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In Vitro Whole Blood Clot Lysis for Fibrinolytic Activity Study Using D-Dimer and Confocal Microscopy by Abuzar Elnager, Wan Zaidah Abdullah, Rosline Hassan, Zamzuri Idris, Nadiah Wan Arfah, S. A. Sulaiman, Zulkifli Mustafa

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Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology by Elena Carmona-Rocha, Lluís Rusiñol, Lluís Puig

“…This narrative review provides a comprehensive synthesis of the pharmacology, clinical efficacy, safety profile, and practical considerations regarding the oral and topical use of PDE4 inhibitors in dermatology.…”
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Computational antidiabetic assessment of Salvia splendens L. polyphenols: SMOTE, ADME, ProTox, docking, and molecular dynamic studies by Hatun A. Alomar, Wafaa M. El Kady, Asmaa A. Mandour, Amany A. Naim, Neveen I. Ghali, Taghreed A. Ibrahim, Noha Fathallah

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Predictive Factors Associated with Inappropriate Intravenous Proton Pump Inhibitors Use in Hospitalized Patients: A Case-Control Study by Niveen Khoury, David Stepensky, Naim Abu Freha, Mahmud Mahamid, Tawfik Khoury, Amir Mari

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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…First, we treated all drugs with a similar pharmacology as the same, rather than assigning their therapeutic value based on year of introduction. …”
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Study on the Role of the Inclusion Complexes with 2-Hydroxypropyl-β-cyclodextrin for Oral Administration of Amiodarone by Andreea Creteanu, Daniela Pamfil, Cornelia Vasile, Gladiola Tantaru, Cristina Mihaela Ghiciuc, Lacramioara Ochiuz, Alina Ghilan, Ana Maria Macsim

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Medicinal plants as alternatives for the management of hypertension and diabetes in Nigeria: Analysis of the structured interview of Nigerian patients by Rosemary A. Sylver-Francis, Olavi Pelkonen

“…The empirical knowledge of this study encourages more research in the search of the pharmacologically effective medicinal plants for the better health management of the Nigerian people.…”
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Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in... by Claudia Stefanutti, Fabio Mazza, Michael Steiner, Gerald F. Watts, Joel De Nève, Daniela Pasqualetti, Juergen Paal

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Bio-protective solutions for carrot spoilage: exploring the antifungal properties of ginger, garlic, onion, and Moringa by Eugenia Njoku, Florence Mbaoji, Justus Nweze, Bonaventure Echezona, Kayode Baiyeri

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An Integrated Approach Exploring the Synergistic Mechanism of Herbal Pairs in a Botanical Dietary Supplement: A Case Study of a Liver Protection Health Food by Liang Chen, Chun Hu, Molly Hood, Juntao Kan, Xiaona Gan, Xue Zhang, Yi Zhang, Jun Du

“…In order to address this question, UPLC-Q-TOF/MS analysis and System Pharmacology tools were applied to explore the mechanism of action, using a White Peony (Paeoniae Radix Alba) and Licorice (Glycyrrhizae Radix et Rhizoma)-based dietary supplement. …”
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In Vitro Evaluation of Ethanolic Extracts of Ageratum conyzoides and Artemisia absinthium against Cattle Tick, Rhipicephalus microplus by S. Parveen, R. Godara, R. Katoch, A. Yadav, P. K. Verma, M. Katoch, N. K. Singh

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Synthesis of Zinc Oxide (ZnO)-Titanium Dioxide (TiO2)-Chitosan-Farnesol Nanocomposites and Assessment of Their Anticancer Potential in Human Leukemic MOLT-4 Cell Line by Abozer Y. Elderdery, Badr Alzahrani, Siddiqa M. A. Hamza, Gomaa Mostafa-Hedeab, Pooi Ling Mok, Suresh Kumar Subbiah

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Cytotoxicity and genotoxicity of orthodontic bands after aging: an in-vitro study by Maryam Karandish, Bahar Khademi, Golnaz Ziaei, Nasrollah Erfani, Leila Moezi, Zahra Faghih

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Histopathologic Evaluation of Nonalcoholic Fatty Liver Disease in Hypothyroidism-Induced Rats by Şule Demir, Mustafa Ünübol, Serap Ünübol Aypak, Emrah İpek, Serdar Aktaş, Gamze Sevri Ekren, Murat Yılmaz, Recai Tunca, Engin Güney

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Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of β-Adrenergic Receptors to Phosphoinositide 3-Kinase by Julie Simard, Matthieu Boucher, Rachel Massé, Terence E. Hébert, Guy Rousseau

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Wound healing potential of green synthesized silver nanoparticles of Glycyrrhiza glabra linn root extract: A preclinical study by Laxman S. Vijapur, Mallappa Shalavadi, Anita R. Desai, Jayadev N. Hiremath, Avinash S. Gudigennavar, Somlingesh L. Shidramshettar, Shreyanka R. Hiremath, Malleswara Rao Peram, Bharatesh S. Kittur

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Migratory Dates, Breeding Phenology, and Reproductive Success of European Turtle Doves between Lowlands and Highest Breeding Habitats in North Africa by Ismail Mansouri, Mohamed Mounir, Wafae Squalli, Laila Elhanafi, Mohamed Dakki, Lahsen El Ghadraoui

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Dietary Chicory Inulin-Rich Meal Exerts Greater Healing Effects than Fructooligosaccharide Preparation in Rats with Trinitrobenzenesulfonic Acid-Induced Necrotic Colitis by Bartosz Fotschki, Adam Jurgoński, Joanna Fotschki, Michał Majewski, Katarzyna Ognik, Jerzy Juśkiewicz

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G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells by Jason M. Conley, Alexander Jochim, Carmella Evans-Molina, Val J. Watts, Hongxia Ren

“…Our studies revealed key signaling mechanisms underlying the role of GPR17 in regulating GLP-1 secretion and suggest future opportunities for pharmacologically targeting GPR17 with inverse agonists to maximize GLP-1 secretion.…”
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