Call for Papers - Advancing Astropharmacy and Sports Pharmacy by Ashley Anderson, Ahmer Raza, Shireen Aziz, Misbah Noreen

“…., (shireenaziz1994@yahoo.com) Shireen Aziz, Pharm.D., MS Pharmacology, is a Ph.D. student in Clinical Pharmacy actively contributing to the I-CARE4OLD project. …”
Get full text

Is Parkinson’s Disease Truly a Prion-Like Disorder? An Appraisal of Current Evidence by Aneesha Chauhan, Alexander F. Jeans

Get full text

Importance of Modulating Kynurenic Acid Metabolism—Approaches for the Treatment of Dementia by Halina Baran, Marcelin Jan Pietryja, Berthold Kepplinger

“…The newly developed <i>Helix pomatia</i> snail model of memory can be used for the assessment of novel pharmacological approaches. Dietary supplementation with natural molecular/herbal extracts, exercise, and physical activity have significant impacts on endogenous pharmacology by reducing kynurenic acid synthesis, and these factors are likely to significantly modulate steady-state biological conditions and delay the negative consequences of aging, including the onset of pathological processes.…”
Get full text

Possible Relevance of Receptor-Receptor Interactions between Viral- and Host-Coded Receptors for Viral-Induced Disease by Luigi F. Agnati, Giuseppina Leo, Susanna Genedani, Diego Guidolin, Nicola Andreoli, Kjell Fuxe

Get full text

Identification of Molecular Substrate for the Attenuation of Anxiety: A Step Toward the Development of Better Anti-Anxiety Drugs by Uwe Rudolph

Get full text

Pancreatic Cancer: What the Oncologist Can Offer for Palliation by Malcolm J Moore

Get full text

Genetic Variants in SNCA and the Risk of Sporadic Parkinson’s Disease and Clinical Outcomes: A Review by Clarissa Loureiro das Chagas Campêlo, Regina Helena Silva

Get full text

Age as a Determinant of the Effectiveness of Intravaginal Sponges Impregnated with Progestin and Equine Chorionic Gonadotropin for Multiple Births Induction of Awassi Ewes by Abbas Daham, Ali Jaber, Jabbar Al-Saaidi

Get full text

PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion by Sebastian Seufert, Roland Coras, Christian Tränkle, Darius P. Zlotos, Ingmar Blümcke, Lars Tatenhorst, Michael T. Heneka, Eric Hahnen

Get full text

Correction: Baradaran Rahimi et al. Anti-Inflammatory and Anti-Oxidant Activity of <i>Portulaca oleracea</i> Extract on LPS-Induced Rat Lung Injury. <i>Molecules</i> 2019, <i>24</i... by Vafa Baradaran Rahimi, Hassan Rakhshandeh, Federica Raucci, Benedetta Buono, Reza Shirazinia, Alireza Samzadeh Kermani, Francesco Maione, Nicola Mascolo, Vahid Reza Askari

Get full text

Advances and Challenges in Cancer Stem Cells for Onco-Therapeutics by Sulaiman Mohammed Alnasser

Get full text

Co-Amoxiclav Induced Immune Haemolytic Anaemia: A Case Report by H. G. C. S. Karunathilaka, D. P. Chandrasiri, P. Ranasinghe, V. Ratnamalala, A. H. N. Fernando

Get full text

Presenting a New Standard Drug Model for Turmeric and Its Prized Extract, Curcumin by Franco Cavaleri

“…Despite the expansive reports of curcucmin’s therapeutic value, clinical reliability and research repeatability with curcumin treatment are still poor. The pharmacology must be better understood and reliably mapped if curcumin is to be accepted and used in modern medical applications. …”
Get full text

Therapy of Inflammatory Bowel Disease using New 5-ASA Compounds: An Introduction by Ulrich Klotz

Get full text

Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence by Suneel Kumar Garg, Omender Singh, Deven Juneja, Niraj Tyagi, Amandeep Singh Khurana, Amit Qamra, Salman Motlekar, Hanmant Barkate

“…Here, we present a literature review of polymyxin B in Gram-negative infections with update on its pharmacology.…”
Get full text

miR-214-3p Deficiency Enhances Caspase-1-Dependent Pyroptosis of Microglia in White Matter Injury by Liufang He, Tingyan Wei, Yong Huang, Xueli Zhang, Dongbo Zhu, Huazhen Liu, Zhangxing Wang

“…Here, we report that the caspase-1 inflammasome is abundantly activated in the microglia of WMI mice and results in increased pyroptosis of microglia. Pharmacology inhibition of caspase-1 cleavage alleviated the pathogenesis of WMI mice. …”
Get full text

MicroRNAs in Human Pituitary Adenomas by Xu-Hui Li, Elaine Lu Wang, Hai-Meng Zhou, Katsuhiko Yoshimoto, Zhi Rong Qian

“…Deregulated miRNAs and their targets contribute to pituitary adenomas progression and are associated with cell cycle control, apoptosis, invasion, and pharmacological treatment of pituitary adenomas. To provide an overview of miRNAs dysregulation and functions of these miRNAs in pituitary adenoma progression, we summarize the deregulated miRNAs and their targets to shed more light on their potential as therapeutic targets and novel biomarkers.…”
Get full text

Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue by Sofia Dias, Sílvia Paredes, Laura Ribeiro

“…Whether solutions to these issues will be found in further adjustments and combinations between drugs already in use or necessarily in new advances in pharmacology is not known. To better understand the effect of drugs used in dyslipidemia and obesity on adipose tissue not only is challenging for physicians but could also be the next step to tackle cardiovascular disease.…”
Get full text

On the Reaction of 2-Alkanoylnaphthohydroquinones with Hydroxylamine: Access to Cytotoxic 2-(Hydroxyamino)-1,4-naphthoquinone and Their 3-(Hydroxyimino)alkyl Analogous by Jaime A. Valderrama, Andrea Pérez-Herrera, Giulio G. Muccioli, Edmundo A. Venegas-Casanova, Rafael Jara-Aguilar, Pedro Buc Calderon, Julio Benites

Get full text

An Audit of Pain Management Following Pediatric Day Surgery at British Columbia Children’s Hospital by Serena Shum, Joanne Lim, Trish Page, Elizabeth Lamb, Jennifer Gow, J Mark Ansermino, Gillian Lauder

Get full text