A Pharmacokinetic/Pharmacodynamic Study of Esomeprazole Comparing a Dual Delayed-Release Formulation (YYD601) to a Conventional Formulation Following Multiple Administrations in Healthy Adult Subjects by Lee HW, Kang WY, Park JS, Lee JH, Park JJ, Gwon MR, Yoon YR, Seong SJ

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LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia by Mihaela Butiulca, Mihaela Butiulca, Lenard Farczadi, Silvia Imre, Silvia Imre, Camil Eugen Vari, Laurian Vlase, Bogdan Cordos, Leonard Azamfirei, Leonard Azamfirei, Alexandra Elena Lazar, Alexandra Elena Lazar

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Liquid Chromatographic–Mass Spectrometric Determination of Ezetimibe in Human Plasma With Validation Approach by Ahmed A. Alobaida

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Preparation and in vivo evaluation of a gel-based nasal delivery system for risperidone by Gu Fugen, Ma Weina, Meng Gendalai, Wu Chunzhi, Wang Yi

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Deep-insights: Nanoengineered gel-based localized drug delivery for arthritis management by Anitha Sriram, Harshada Ithape, Pankaj Kumar Singh

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Combining solubilization and controlled release strategies to prepare pH-sensitive solid dispersion loaded with albendazole: in vitro and in vivo studies by Dehai Su, Mingyang Bai, Chaoqun Wei, Xiangyang Long, Xuezhen Liu, Xiangguang Shen, Huanzhong Ding

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Using drinking data and pharmacokinetic modeling to calibrate transport model and blind deconvolution based data analysis software for transdermal alcohol biosensors by Zheng Dai, I.G. Rosen, Chuming Wang, Nancy Barnett, Susan E. Luczak

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Investigation of Pharmacokinetic Parameters of Trelagliptin in Egyptian Volunteers Using Sensitive LC-MS/MS: A Comparative Study with a Japanese Population by Shereen Mowaka, Nermeen Ashoush, Mariam M. Tadros, Bassam M. Ayoub

“…The proposed method was successfully applied to a pharmacokinetic study conducted on Egyptian volunteers. …”
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Pharmacokinetic Study of Di-Phenyl-Di-(2,4-Difluobenzohydroxamato)Tin(IV): Novel Metal-Based Complex with Promising Antitumor Potential by Yunlan Li, Zhuyan Gao, Pu Guo, Qingshan Li

“…The method was used to determine the concentration-time profiles for DPDFT in the plasma after single intravenous administration with doses of 5, 10, 15 mg·kg-1 to rats. The pharmacokinetics parameter calculations and modeling were carried out using the 3p97 software. …”
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Chimerism in Myeloid Malignancies following Stem Cell Transplantation Using FluBu4 with and without Busulfan Pharmacokinetics versus BuCy by Shatha Farhan, Michael Bazydlo, Klodiana Neme, Nancy Mikulandric, Edward Peres, Nalini Janakiraman

“…We undertook a retrospective analysis of 78 patients with myeloid malignancies who received fludarabine and busulfan (FluBu4) with or without measuring Bu pharmacokinetics (Bu PK) and those who received busulfan with cyclophosphamide (BuCy). …”
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Evaluation of the Effects of Astragalus membranaceus on the Pharmacokinetics of Pemetrexed Disodium and Gemcitabine in Rats by a Simple High-Performance Liquid Chromatography/UV Method by Zixuan Chu, Zhiyuan Wang, Teng Liu, Shan Xiong, Bin Liu

“…There were no significant differences in pharmacokinetic parameters of pemetrexed disodium between the Astragalus extract treatment group and the control group. …”
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Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin by Guozhe Zhang, Jianwei Ji, Mingzhong Sun, Yuqiao Ji, Hongjian Ji

“…In this study, the pharmacokinetics of orally administered puerarin (100 mg/kg) and PLE (763 mg/kg, equivalent to 100.0 mg/kg of puerarin) to rats was investigated by the UHPLC-MS/MS method. …”
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In vivo imaging and pharmacokinetics of percutaneously injected ultrasound and X-ray imageable thermosensitive hydrogel loaded with doxorubicin versus free drug in swine. by Jose F Delgado, Ayele H Negussie, Nicole A Varble, Andrew S Mikhail, Antonio Arrichiello, Tabea Borde, Laetitia Saccenti, Ivane Bakhutashvili, Joshua W Owen, Robert Morhard, John W Karanian, William F Pritchard, Bradford J Wood

“…Notably, 3D reconstruction of the distribution of POL and POLDOX from 2D ultrasound frames was achieved and morphometric data obtained. Pharmacokinetic analysis revealed lower systemic exposure of the drug in various organs with POLDOX formulation compared to DOXSoln formulation. …”
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Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs by Lin Wang, Jiaxi Wang, Chao Lin, Furong Wang, Xiangping Li, Wanhui Liu

“…The validated method was then successfully applied to pharmacokinetic study of pioglitazone combined with omarigliptin in rats. …”
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Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 by Marx Ribeiro, Juliana Cordeiro Cardoso, José Eduardo Severino Martins, Aline Ferreira Pinto, Eliana Maria Barbosa Souto, Patricia Severino

“…Abstract The landscape of scientific research in Latin America (LA), particularly in the realms of the Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutic models (PBPM), is a mosaic of varied contributions, collaborations, and specializations. …”
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Voriconazole Pharmacokinetics Administered at 4 mg/kg IM and IV in Nursehound Sharks (<i>Scyliorhinus stellaris</i>) Under Human Care by Daniela Cañizares-Cooz, Daniel García-Párraga, Sonia Rubio-Langre, Teresa Encinas, Pablo Morón-Elorza

“…Plasma concentrations were determined using a validated high-performance liquid chromatography (HPLC) method, and pharmacokinetic (PK) parameters were estimated using a non-compartmental model. …”
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The evaluation of pharmacokinetic parameters of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide and its metabolites in rat plasma by Alexander L. Khokhlov, Ilya I. Yaichkov, Anton A. Shetnev, Mikhail K. Korsakov, Nikita N. Volkhin, Sergey S. Petukhov, Alena N. Tyushina, Olga E. Lasaryanz

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Effect of Staggered vs. Simultaneous Co-Administration of Bempedoic Acid on Pharmacokinetics of Pravastatin: Randomized, Cross-Over Clinical Trial in Healthy Volunteers by Felicitas Stoll, Salvatore Amato, Max Sauter, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli, Antje Blank

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A single-centre randomised controlled trial comparing the standard method and target-controlled infusion as a method of administering cefoxitin, which is used to prevent surgical s... by Ha-Jung Kim, Kyung Mi Kim, Jong Lyul Lee, In Ja Park, Byung-Moon Choi

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Bioavailability study of enantiopure (S)-Equol in CD(SD)IGS rats by Seethakallu Ramachandraiah AnandaKumar, Mukund Handral, Srinivas Seekallu

Subjects: “…Pharmacokinetic…”
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