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Pharmacodynamic Modeling of Warfarin Dosing Algorithm for Cardiovascular Patients in Indonesia: A Tailored Method to Anticoagulation Therapy
Published 2025-01-01“…Norisca Aliza Putriana,1 Irma Rahayu Latarissa,2 Taofik Rusdiana,1 Tina Rostinawati,3 Mohammad Rizki Akbar4 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 3Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 4Department of Cardiovascular, Faculty of Medicine, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Norisca Aliza Putriana, Department of Pharmaceuticals and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Jl. …”
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Dietary phytochemicals alleviate the premature skin aging: A comprehensive review
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Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes
Published 2025-01-01“…Here, we hypothesized that administration of pharmaceutical-grade human AAT (hAAT) is effective in mitigating hypertension induced by salt-loading in juvenile mice by reducing the concentration of diacylglycerols (DAGs) and activity of protein kinase C (PKC) in the kidney.MethodsFour-week old 129Sv mice were salt-loaded to induce hypertension and then administered hAAT or vehicle.ResultsAdministration of hAAT was found to significantly reduce high blood pressure in both the active and inactive cycles of the 129Sv hypertensive mice. …”
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Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment
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Alopecia Management Potential of Rosemary-Based Nanoemulgel Loaded with Metformin: Approach Combining Active Essential Oil and Repurposed Drug
Published 2025-01-01“…Kawthar K Abla,1 Mariam K Alamoudi,2 Gamal A Soliman,2,3 Maged S Abdel-Kader,4,5 Mohammed F Aldawsari,6 Mohammed M Mehanna7,8 1Department of Pharmaceutical Science, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon; 2Department of Pharmacology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 3Department of Pharmacology, College of Veterinary Medicine, Cairo University, Giza, Egypt; 4Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 5Department of Pharmacognosy, College of Pharmacy, Alexandria University, Alexandria, Egypt; 6Department Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 7Department of Pharmaceutical Sciences, School of Pharmacy, Lebanese American University, Byblos, Lebanon; 8Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptCorrespondence: Mohammed M Mehanna, Department of Industrial Pharmacy, Alexandria University, Alexandria, Egypt, Email mohamed.mehanna@alexu.edu.egIntroduction: Androgenetic alopecia (AGA) is a multifactorial and age-related dermatological disease that affects both males and females, usually at older ages. …”
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Scopoletin as a cardioprotective agent against cisplatin-induced oxidative stress and inflammation
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Combining In Vitro, In Vivo, and In Silico Approaches to Explore the Effect of <i>Ceratonia siliqua</i> and <i>Ocimum basilicum</i> Rich Phenolic Formula on Lipid Metabolism and Pl...
Published 2025-01-01“…Conclusions: The CBF could be a good source of natural supplements, functional foods, and pharmaceuticals effective in managing hyperlipidemia and oxidative stress and preventing their related cardiovascular disorders.…”
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Fusidic Acid and Lidocaine-Loaded Electrospun Nanofibers as a Dressing for Accelerated Healing of Infected Wounds
Published 2025-01-01“…Khulud A Alsulami,1 Abrar A Bakr,1 Alaa Sirwi,2 Mahmoud A Elfaky,2 Rasheed A Shaik,3 Bayan Y Alshehri,1 Alhassan H Aodah,1 Nojoud Al Fayez,1 Abdullah A Alshehri,1 Fahad A Almughem,1 Abdulrahman A Halwani,4,5 Essam A Tawfik1 1Advanced Diagnostics and Therapeutics Institute, Health Sector, King Abdulaziz City for Science and Technology (KACST), Riyadh, 11442, Saudi Arabia; 2Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 3Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 4Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 5Regenerative Medicine Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, 21589, Saudi ArabiaCorrespondence: Essam A Tawfik, Email etawfik@kacst.gov.saIntroduction: Wound treatment is a significant health burden in any healthcare system, which requires proper management to minimize pain and prevent bacterial infections that can complicate the wound healing process.Rationale: There is a need to develop innovative therapies to accelerate wound healing cost-effectively. …”
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Mechanism of the blood-brain barrier modulation by cadherin peptides
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Phytochemical investigation and evaluation of antioxidant and antidiabetic activities in aqueous extracts of Cedrus atlantica
Published 2025-01-01“…These extracts possess various phytochemical compounds with significant antioxidant capacities, suggesting that they are suitable for pharmaceutical, nutraceutical, and cosmetic applications. …”
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