Editorial: Five grand challenges in toxicology by Bengt Fadeel, Jan Alexander, Sara C. Antunes, Kim Dalhoff, Ellen Fritsche, Ellen Fritsche, Helena T. Hogberg, François Huaux, Stina Oredsson, Antonio Pietroiusti, Terje Svingen, Martin F. Wilks, Martin F. Wilks

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Involvement of different protein kinases and phospholipases A2 in phorbol ester (TPA)-induced arachidonic acid liberation in bovine platelets by M. Lehr, K. Griessbach

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Synergistic effects of mutation and glycosylation on disease progression by Shodai Suzuki, Motoyuki Itoh, Motoyuki Itoh, Motoyuki Itoh

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On increasing students’ motivation for studying English as a foreign language at university by Nadezhda G. Pirogova, Grigory A. Rozhkov

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Piecewise function parameters as responses of the design of experiment in the development of a pulsatile release chronopharmaceutical system by Vonica-Gligor Andreea Loredana, Tomuţă Ioan, Leucuţa Sorin E.

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Roles of nanotechnology in electrochemical sensors for medical diagnostic purposes: A review by Ali R. Jalalvand, Mohammad Mehdi Karami

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Mechanisms Underlying Tolerance after Long-Term Benzodiazepine Use: A Future for Subtype-Selective GABAA Receptor Modulators? by Christiaan H. Vinkers, Berend Olivier

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Investigating new drugs from marine seaweed metabolites for cervical cancer therapy by molecular dynamic modeling approach by Sk Injamamul Islam, Sheikh Sunzid Ahmed, Sarower Mahfuj, Gunjan Das, Md. Mohaimenul Islam Tareq, Mazen Almehmadi, Mamdouh Allahyani, Naif Alsiwiehri, Partha Biswas, Md. Nazmul Hasan, Foysal Ahammad

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Toxicological Assessment of Pseudospondias microcarpa (A. Rich.) Engl. Hydroethanolic Leaf Extract in Rats: Haematological, Biochemical, and Histopathological Studies by Donatus Wewura Adongo, Priscilla Kolibea Mante, Kennedy Kwami Edem Kukuia, Charles Kwaku Benneh, Robert Peter Biney, Eric Boakye-Gyasi, Nicholas Akinwale Titiloye, Eric Woode

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Voice analysis and deep learning for detecting mental disorders in pregnant women: a cross-sectional study by Hikaru Ooba, Jota Maki, Hisashi Masuyama

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Regulation of Recombination between gtfB/gtfC Genes in Streptococcus mutans by Recombinase A by Satoko Inagaki, Kazuyo Fujita, Yukiko Takashima, Kayoko Nagayama, Arifah C. Ardin, Yuki Matsumi, Michiyo Matsumoto-Nakano

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Cimetidine Pharmacodynamics and Pharmacokinetics in Healthy Subjects: A Comparison of Tablets and Suspension by ABR Thomson, P Kirdeikis, L Zuk, RE Samuels, P Zarevics

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Regulation of S100A8/A9 (Calprotectin) Binding to Tumor Cells by Zinc Ion and Its Implication for Apoptosis-Inducing Activity by Yuichi Nakatani, Masatoshi Yamazaki, Walter J. Chazin, Satoru Yui

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From Bitter to Sweet: a preliminary study towards a patient-friendly Praziquantel dosage form by Zanolla, Debora, Bertoni, Serena, Passerini, Nadia, Albertini, Beatrice, Zingone, Guglielmo, Perissutti, Beatrice

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Efficacy and safety of anti-thrombotic therapy after surgical mitral valve repair: a scoping review by Jian Ye, Jenny Chen, Hazal Ece Babadagli, Ricky Turgeon, Erica HZ Wang

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Four-color single-molecule imaging system for tracking GPCR dynamics with fluorescent HiBiT peptide by Toshiki Yoda, Yasushi Sako, Asuka Inoue, Masataka Yanagawa

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Comparative Evaluation of Cyclooxygenase Inhibition Profiles Across Various NSAID Forms and Doses: Implications for Efficacy and Adverse Effects by Kenshu Shirakawa, Masafumi Takeno, Hidekazu Kuma, Takaaki Terahara, Shigeki Yamaguchi

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In Silico and In Vitro Inhibitory Activity of Indonesian Herbal Compound Extracts against SARS-COV-2 Recombinant Papain-Like Protease by Fairuz Andini Fatiningtyas, Riswanto Napitupulu, Amarila Malik, Is Helianti

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Reduction of monoclonal antibody viscosity using interpretable machine learning by Emily K. Makowski, Hsin-Ting Chen, Tiexin Wang, Lina Wu, Jie Huang, Marissa Mock, Patrick Underhill, Emma Pelegri-O’Day, Erick Maglalang, Dwight Winters, Peter M. Tessier

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Personal, occupational and cardiovascular risk factors associated with elevated blood pressure in Brazilian firefighters: a cross-sectional study by Eliana Zandonade, Fernanda Camargo Damacena, Karla Nívea Sampaio, Igor Magalhães Sales

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