Two chromatographic methods for analyzing paracetamol in spiked human plasma with its toxic metabolite, N-acetyl parabenzoquinone imine and its antidote, N-acetyl-l-cysteine by Omar M El-Abassy, Michael Gamal Fawzy, Ebraam B. Kamel

“…Abstract Acetaminophen, also known as paracetamol (APAP), is a highly utilized pharmaceutical agent on a global scale, particularly in the field of pediatrics. …”
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Biomarker Profiling for Pyridoxine Dependent Epilepsy in Dried Blood Spots by HILIC-ESI-MS by Elizabeth Mary Mathew, Sudheer Moorkoth, Leslie Lewis, Pragna Rao

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Approaches and applications in transdermal and transpulmonary gene drug delivery by Anni Zhang, Xuran Zhang, Jiahui Chen, Xianbao Shi, Xijuan Yu, Zhonggui He, Zhonggui He, Jin Sun, Jin Sun, Mengchi Sun, Mengchi Sun, Zhijun Liu

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High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota by Yu Xia, Yu Xia, Lulu Wang, Yanyan Qiu, Weihong Ge, Weihong Ge, Weihong Ge

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Antioxidative Reactivity of L-Ascorbic Acid and D-Isoascorbic Acid Species towards Reduction of Hexachloroiridate (IV) by Han Zhang, Yanqing Xia, Peng Zhang, Liqian Hou, Ying Sun, Zhaozhan Lu, Yunfeng Tang, Hongwu Tian, Tiesheng Shi

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Usability Evaluation of Foods with Function Claims Labelling as Health Information in Japan: A User-Testing Study by Yamamoto M, Yamamoto K, Takano-Ohmuro H, Yamamoto R, Saruwatari J

“…Michiko Yamamoto,1,* Ken Yamamoto,2,* Hiromi Takano-Ohmuro,3 Rain Yamamoto,4 Junji Saruwatari1 1Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto-city, Kumamoto, Japan; 2Showa Pharmaceutical University, Machida-city, Tokyo, Japan; 3Faculty of Pharmacy, Musashino University, Nishitokyo-city, Tokyo, Japan; 4Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan*These authors contributed equally to this workCorrespondence: Michiko Yamamoto, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto-city, Kumamoto, Japan, Email m-yamamoto@kumamoto-u.ac.jpPurpose: The saturation of health foods in the market is coupled with inadequate information on their safe usage. …”
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The Burden of Illness in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease in Canada by M Reza Maleki-Yazdi, Suzanne M Kelly, Sy S Lam, Mihaela Marin, Martin Barbeau, Valery Walker

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A Case for Rimantadine to Be Marketed in Canada for Prophylaxis of Influenza a Virus Infection by Fawziah Marra, Carlo A Marra, H Grant Stiver

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Spectrophotometric Determination of Ezetimibe by P. Baby Sudha Lakshmi, D. Ramchandran, C. Rambabu

“…Two simple, sensitive, selective and accurate spectro-photometric methods (Method A and Method B) for the determination of eztimibe in bulk drug and pharmaceutical formulations (tablets) have been described. …”
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Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations by Sherif Elhosseiny, Hassan Al Moussawi, Jean M. Chalhoub, James Lafferty, Liliane Deeb

“…The introduction of Direct Oral Anticoagulants (DOACs) to the pharmaceutical market provided patients and clinicians with novel convenient and safe options of anticoagulation. …”
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Suspected Intramural Spread of Dye during Transaortic Celiac Plexus Rhizolysis in Patient of Intra-abdominal Malignancy by Anurag Agarwal, Shivani Rastogi, Brihaspati Tiwari, Aayushi Bagga

“…A minimally invasive pain intervention, such as celiac plexus rhizolysis, may be needed to treat individuals whose pain is resistant to pharmaceutical therapy. Although celiac plexus rhizolysis is an effective and relatively safer technique, fatal complications such as aortic pseudoaneurysm or dissection are possible. …”
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Development of Class IIa Bacteriocins as Therapeutic Agents by Christopher T. Lohans, John C. Vederas

“…The suitability of bacteriocins as pharmaceuticals is explored through determinations of cytotoxicity, effects on the natural microbiota, and in vivo efficacy in mouse models. …”
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A shortage of funding or not enough healthcare projects? by Mike Eaton

“…1727462674"> The author, having worked in pharmaceuticals for several decades, has advised, in confidence, both investors and small to medium-sized enterprises on transitioning healthcare research projects into commercial development, mainly in Europe. …”
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New frontiers in CRISPR: Addressing antimicrobial resistance with Cas9, Cas12, Cas13, and Cas14 by Ahmed S.A. Ali Agha, Ali Al-Samydai, Talal Aburjai

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Resistant Starch Contents of Native and Heat-Moisture Treated Jackfruit Seed Starch by Ornanong S. Kittipongpatana, Nisit Kittipongpatana

“…Native jackfruit seed starch (JFS) contains 30% w/w type II resistant starch (RS2) and can potentially be developed as a new commercial source of RS for food and pharmaceutical application. Heat-moisture treatment (HMT) was explored as a mean to increase RS content of native JFS. …”
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Roles of Pyruvate, NADH, and Mitochondrial Complex I in Redox Balance and Imbalance in β Cell Function and Dysfunction by Xiaoting Luo, Rongrong Li, Liang-Jun Yan

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Analysis of doxorubicin and fullerenol in rat serum by micellar electrokinetic capillary chromatography by Injac Rade, Sertić Miranda, Glavač Nina Kočevar

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Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

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Manufacturing of Human Umbilical Cord Mesenchymal Stromal Cells on Microcarriers in a Dynamic System for Clinical Use by Florian Petry, J. Robert Smith, Jasmin Leber, Denise Salzig, Peter Czermak, Mark L. Weiss

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Eco-sustainable chromatographic method for the determination of favipiravir and nitazoxanide for COVID-19: application to human plasma by Amal B. Ahmed, Maha M. Abdelrahman, Fadwa H. Edrees

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