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    Development and validation of a new reverse-phase high-performance liquid chromatography (RP-HPLC) method for the quantifications of tolperisone loaded in liposomes by Rawan N. AlKaraki, Rula R. Haddadin, Shahed K. Tarawneh, Marwa A.M. Alimari, Rehan M. Alkasasbeh, Tebat Al-ferdous E. Shamaileh, Mustafa S. Almohtaseb, Malek G. Hajaya

    Published 2025-03-01
    “…The method's applicability was demonstrated by accurately quantifying TOL content in a commercial pharmaceutical formulation. The validated RP-HPLC method was used to demonstrate the suitability of liposomes as a carrier for TOL by evaluating its entrapment efficiency (14.76 %), along with achieving a slower drug in-vitro cumulative percentage release in the targeted media (compared to free TOL solution) from the liposomes.…”
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