The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…Patients are randomised equally to receive two capsules of lansoprazole or two placebo capsules, two times per day for 12 months. The primary outcome for the trial is change in FVC, measured at home, between the first week and last week of the study period. …”
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Effects of cage size on the natural behavior, serum parameters, production performance and hypothalamic mRNA expression profiles of laying hens by Yi Wan, Ruiyu Ma, Renrong Qi, Dawei Jiang, Helong Guan, Wei Liu, Junying Li, Yan Li, Kai Zhan

“…Behavioral expression was evaluated through observation of only six birds per group on a weekly basis. Compared to the SC group, the average frequencies of walking, wing-flapping, feather-pecking and drinking significantly increased in the LC and MC groups (P <0.05), whereas the average frequency of stereotypic behavior significantly decreased (P <0.05), indicating that cage size has positive effects on natural behavior. …”
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Impact of witnessing abuse of their mother and childhood trauma on men's perpetration of intimate partner violence in the cross-sectional UN multi-country study on men and violence... by Rachel Jewkes, Ruchira Tabassum Naved, Naeema Abrahams, Nwabisa Shai, Leane Ramsoomar, Bianca Dekel, Andrew Gibbs, Jani Nöthling, Samantha Willan, Esnat Chirwa

“…Methods: In nine sites, from six countries, data were collected in a two-stage, randomly-selected household survey, with one man aged 18–49 years interviewed per house. 8379 interviews were completed with ever partnered men in Bangladesh, Cambodia, China, Indonesia, Papua New Guinea (Bougainville) and Sri Lanka. …”
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“Holding on to Hope”: follow up qualitative findings of a tobacco treatment intervention for people experiencing mental health conditions by Tessa-May Zirnsak, Kristen McCarter, Melissa L. McKinlay, Ashleigh Guillaumier, Nadine Cocks, Catherine Brasier, Laura Hayes, Amanda L. Baker, Donita E. Baird, Billie Bonevski, Ron Borland, Ron Borland, David Castle, Erin Forbes, Peter J. Kelly, Catherine Segan, Catherine Segan, Rohan Sweeney, Alyna Turner, Alyna Turner, Jill M. Williams, Lisa Brophy, Lisa Brophy

“…Connectedness and hope are significant enablers of making and sustaining quit attempts.Trial registrationThe Quitlink trial was registered with ANZCTR (www.anzctr.org.au): ACTRN12619000244101 prior to the accrual of the first participant and updated regularly as per registry guidelines.…”
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Tryptophan and/or canthaxanthin in quail diets: effects on performance, carcass traits, hematology, blood chemistry and hepatic antioxidant capacity by Khaled H. El-Kholy, Mohamed E. Sokariaa, Mohammed F. El Basuini, Sara F. Fouda, Tarek A. Ebeid, Ibrahim T. El-Ratel, Mahmoud M. Azzam, Alessandro Di Cerbo, Ahmed A. Elolimy, Mahmoud Madkour, Mahmoud Alagawany

“…Each group consisted of five replicates, with 10 birds per replicate. Chicks in group 1 (T1) served as the control and were fed a basal diet without any supplementation from week 1 to week 5. …”
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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

“…Those patients with a monthly family income of 1000–2999¥ (US$161–482) per capita constituted the largest patient population. …”
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PASS: A scoring system to evaluate persistent kidney injury in critically ill ICU adult patients [version 3; peer review: 2 approved, 1 not approved] by Chakrapani Mahabala, Sonali Dattatray Prabhu, Mayoor V Prabhu, Dattatray Prabhu

“…Patients were managed as per standard protocol. After six hours of fluid resuscitation, patients were classified as volume responders or non-responders. …”
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Chemokines Profiling of Patients with Preterm Birth by Piotr Laudanski, Adam Lemancewicz, Pawel Kuc, Karol Charkiewicz, Barbara Ramotowska, Malgorzata Kretowska, Elwira Jasinska, Grzegorz Raba, Katarzyna Karwasik-Kajszczarek, Janusz Kraczkowski, Tadeusz Laudanski

“…To assess the concentration of chemokines in the blood serum, we used a multiplex method, which allows the simultaneous determination of 40 chemokines per sample. The sets consist of the following chemokines: 6Ckine/CCL21, Axl, BTC, CCL28, CTACK/CCL27, CXCL16, ENA-78/CXCL5, Eotaxin-3/CCL26, GCP-2/CXC, GRO (GROα/CXCL1, GROβ/CXCL2 and GROγ/CXCL3), HCC-1/CCL14, HCC-4/CCL16, IL-9, IL-17F, IL18-BPa, IL-28A, IL-29, IL-31, IP-10/CXCL10, I-TAC/CXCL11, LIF, LIGHT/TNFSF14, Lymphotactin/XCL1, MCP-2/CCL8, MCP-3/CCL7, MCP-4/CCL13, MDC/CCL22, MIF, MIP-3α/CCL20, MIP-3-β/CCL19, MPIF-1/CCL23, NAP-2/CXCL7, MSPα, OPN, PARC/CCL18, PF4, SDF-1/CXCL12, TARC/CCL17, TECK/CCL25, and TSLP. …”
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Association between chiropractic spinal manipulative therapy and benzodiazepine prescription in patients with radicular low back pain: a retrospective cohort study using real-world... by Jeffery A Dusek, Robert James Trager, Zachary A Cupler, Kayla J DeLano, Jaime A Perez

“…Propensity score matching was used to control for covariates that could influence the likelihood of benzodiazepine utilisation.Outcome measures The number, percentage and OR of patients receiving a benzodiazepine prescription over 3, 6 and 12 months’ follow-up prematching and postmatching.Results After matching, there were 9206 patients (mean (SD) age, 37.6 (8.3) years, 54% male) per cohort. Odds of receiving a benzodiazepine prescription were significantly lower in the CSMT cohort over all follow-up windows prematching and postmatching (p&lt;0.0001). …”
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Evaluation of the rainfed and irrigated conditions on biomass and essential oil yield of German chamomile (Matricaria chamomilla) in response to melatonin foliar application by Hossein Gorgini Shabankareh, Mohammad Reza Asgharipour, Ali Salehi Sardoei, Ahmad Reza Kamaliun, Hamid Mohammadi, Mansour Ghorbanpour

“…Under irrigated conditions, the highest essential oil yield of 0.33 g per plant was also achieved with 100 mM melatonin. …”
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Effect of Extracorporeal Shock Wave combined with Occupational Therapy on Forearm Pronation Disorder in Children with Spastic Cerebral Palsy by Hezeng LIU, Yong ZHAO, Bingxu JIN, Chuntao ZHANG, Yang YANG, Miaotao WU, Xiaoli WANG, Jixiang CHENG

“…Objective:To observe the effect of extracorporeal shock wave combined with occupational therapy therapy on forearm pronation disorder in children with spastic cerebral palsy(SCP).Methods:A total of 42 children with SCP were randomly divided into the control group and the observation group, with 21 cases in each group in the children rehabilitation department of the affiliated Nanhai maternity and children's Hospital of Guangzhou university of traditional Chinese medicine from January to December 2019.The control group was given targeted occupational therapy, including upper limb forearm pronator stretching therapy, neurophysiological therapy(Bobath technology), proprioceptive neuromuscular facilitation therapy(PNF); game type occupational training including placing objects in forearm supination position, supination grasping stick, supination fetching game, palm and back game, etc..The above training was conducted once a day, 30 minutes per time, six times a week, three months as a course of treatment, continuous treatment for two courses.The observation group was given extracorporeal shock wave therapy on the basis of the control group.The child with SCP was in a comfortable position and the forearms of the upper limbs were placed on the plane so that it could free its own gravity.The abdomen of pronator teres muscle was impacted with the probe of shock wave therapeutic instrument(pressure intensity: 1.0-1.5 bar;frequency: 8-10 Hz;impact times: 1 000-2 000 times).Three to five minutes each time, once every three days, twice a week, three months as a course of treatment, continuous treatment for two courses.Before treatment, after treatment for three months and six months, the modified Ashworth scale(MAS)was used to evaluate the spasticity of forearm pronator muscles;the active range of motion(AROM)of forearm supination was measured by joint range of motion protractor;and the fine motor quotient(FMQ)of hands was evaluated by Peabody development motor scale-fine motor(PDMS-FM).Results:Before treatment, there was no significant difference in MAS score, AROM angle and FMQ score between two groups(<italic>P</italic>&gt;0.05).Compared with before treatment, the MAS scores of the two groups decreased significantly after treatment for three and six months, and the AROM angle and FMQ score increased significantly, the difference was statistically significant(<italic>P</italic>&lt;0.05).Compared with the control group at the same time after treatment, MAS score of the observation group was significantly lower, AROM angle and FMQ score were significantly higher, the difference was statistically significant(<italic>P</italic>&lt;0.05).Conclusion:Extracorporeal shock wave combined with occupational therapy therapy can effectively improve the degree of upper limb spasticity and forearm supination joint activity in children with spastic cerebral palsy, and improve the fine motor function of hands.…”
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Association between some environmental risk factors and attention-deficit hyperactivity disorder among children in Egypt: a case-control study by Riham Abdelhamid Hussein, Rania Hussein Refai, Aleya Hanafy El-zoka, Hanan Galal Azouz, Mohamed Fakhry Hussein

“…The logistic regression model revealed that six factors had a significant association with ADHD: using of newspapers to wrap food 3 or more times a week (adjusted odds ratio (AOR) = 105.11, 95% CI: 11.18-988.26), daily TV watching by child for more than 5 h (AOR = 63.96, 95% CI: 2.56-1601.32), child’s eating commercially packed noodles 3 times or more per week (AOR = 57.73, 95% CI: 3.77–593.93), using unpackaged flour in cooking (AOR = 44.47, 95% CI: 1.83–629.80), eating sweets daily by child (AOR = 6.82, 95% CI: 1.23–37.94), and lastly elevated hair Manganese level (AOR = 3.57, 95% CI: 1.24–10.29). …”
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A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system. by Ellen T Heyman, Awais Ashfaq, Ulf Ekelund, Mattias Ohlsson, Jonas Björk, Ardavan M Khoshnood, Markus Lingman

“…., registered clinical data with time stamps, per ED visit was 1,095 (IQR 459-2,310). CareNet median AUROC was 87.0%, substantially higher than the CatBoost model´s (81.4%). …”
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Hybrid Nanocomposite Mini-Tablet to Be Applied into the Post-Extraction Socket: Matching the Potentialities of Resveratrol-Loaded Lipid Nanoparticles and Hydroxyapatite to Promote... by Viviana De Caro, Giada Tranchida, Cecilia La Mantia, Bartolomeo Megna, Giuseppe Angellotti, Giulia Di Prima

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Ratio-dependent competitions between a Wolbachia-uninfected bisexual strain and Wolbachia-infected thelytokous strain of the egg parasitoid, Trichogramma dendrolimi Matsumura (Hyme... by Qian-Jin Dong, Yue He, Yu-Zhe Dong, Wu-Nan Che, Jin-Cheng Zhou, Hui Dong

“…Results This study examined the parasitic capacities of bisexual (TdB) and Wolbachia-infected thelytokous (TdT) strains of Trichogramma dendrolimi as influenced by host density (ranging from 5 to 70 host eggs) and wasp density (two, four, and six females per arena). The experiments involved inter-strain competition between TdB and TdT strains (Inter-Td) as well as intra-strain competition within the TdT (Intra-TdT) or TdB (Intra-TdB) strains. …”
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In Vivo Corneal Confocal Microscopy Detects Improvement of Corneal Nerve Parameters following Glycemic Control in Patients with Type 2 Diabetes by Xiaofan Jia, Xiaogang Wang, Xiaoxia Wang, Qi Pan, Tongzhang Xian, Xiaobin Yu, Lixin Guo

“…Thirty-two patients with diabetes complicated by DPN and 12 age-matched control subjects underwent detailed clinical examination and were assessed per the Toronto Clinical Scoring Scale for DPN, nerve conduction studies, and IVCCM at baseline and after approximately one year from the first visit. …”
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Exploring Web-Based Support for Suicidal Ideation in the Scottish Population: Usability Study by Heather McClelland, Rory C O'Connor, Laura Gibson, Donald J MacIntyre

“…On average, the website received 99.9 visitors per day. A total of 56% (n=14,439) of visitors were female, ages ranged from younger than 18 years to older than 70 years (commonly between 25 and 34 years) and originated from all regions of Scotland. …”
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An underground coal mine multi-target detection algorithm by FAN Shoujun, CHEN Xilin, WEI Liangyue, WANG Qingyu, ZHANG Shiyuan, DONG Fei, LEI Shaohua

“…The results showed that: ① The mAP@0.5 of the FEDSC-FFBD algorithm was 97.00%, the number of model parameters was 4.22×106, and the number of floating point operations per second was 21.7×109. ② The mAP@0.5 of the FEDSC-FFBD alorithm was 3.40% higher than the YOLOv8n algorithm, and the recognition accuracy of the helmet small target was 90.90%, 11% higher than the YOLOv8n algorithm. ③ Compared with other YOLO series algorithms, the FEDSC-FFBD algorithm achieved the highest mAP@0.5, which was 3.60%, 1%, 10.50%, and 6.40% higher than YOLOv5s, YOLOv9c, YOLOv10n, and YOLOv11n algorithms, respectively. ④ The FEDSC-FFBD algorithm improved the detection accuracy of multi-class targets and reduced missed detection and false detection of small targets under conditions of uneven light intensity distribution, complex target environments, and imbalanced target scale distribution in underground coal mine. …”
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Aero-Thermodynamics of UAV Downwash for Dynamic Microclimate Engineering: Ameliorating Effects on Rice Growth, Yield, and Physiological Traits Across Key Growth Stages by Imran, Liang Ke, Dong Liu, Huifen Li, Jiyu Li

“…Key agronomic parameters showed significant improvements, including stem diameter, canopy temperature regulation, grain filling duration, productive tillers (increasing by 30.77%), total tillers, flag leaf area, grains per panicle (rising by 46.55%), biological yield, grain yield (surging by 70.75%), and harvest index. …”
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Analysis of Chinese adult residents receiving healthy lifestyle advice from medical institutions by Huiyan SUN, Limin WANG, Chun LI, Xiao ZHANG, Zhenping ZHAO, Mei ZHANG

“…Significant differences (all P < 0.05) were found among different annual per capita household income levels regarding advice on salt reduction, adequate fruit and vegetable intake, fat reduction, adequate exercise, and healthy weight. …”
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