Cost-utility of behavioural activation for mitigating psychological impacts of COVID-19 on socially isolated older adults with depression and multiple long-term conditions compared... by Simon Gilbody, Caroline Fairhurst, Catherine Hewitt, Dean McMillan, Carolyn Chew-Graham, Della Bailey, David Ekers, Steve Parrott, Elizabeth Littlewood, Peter Coventry, Han-I Wang, Kalpita Baird

“…Sensitivity analyses were conducted to assess the robustness of the primary analysis.Findings Primary analysis indicated that BA generated a small cost-saving (£62.34 per older adult; 95% CI: −£120.44 to £239.70) while QALY improvements remained unchanged (0.007; 95% CI −0.036 to 0.022) compared with usual care. …”
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Being a tree crop increases the odds of experiencing yield declines irrespective of pollinator dependence by Aizen, Marcelo A., Gleiser, Gabriela, Kitzberger, Thomas A., Milla, Ruben

“…Crop yields, i.e. harvestable production per unit of cropland area, are in decline for a number of crops and regions, but the drivers of this process are poorly known. …”
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Patient–specific hemodynamic modeling to optimize LVAD speed and right heart health by Mustafa M. Ahmed, Holly Grant, Jasmine Martinez, Joshua Thomas, Mohammad Al-Ani, Alex Parker, Juan Vilaro, Juan Aranda, Venkat Keshav Chivukula

“…Results: All patients who underwent RHC speed titration had a clinician–guided speed increase, with a median increase of 300 revolutions per minute (rpm). Using each patient’s customized VHM, virtual speed optimization demonstrated congruence with clinician-guided optimization, with a median predicted speed increase of 321 rpm. …”
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Supplementation with essential amino acids in the early stage of carbohydrate reintroduction after a very-low energy ketogenic therapy (VLEKT) improves body cell mass, muscle stren... by Giuseppe Annunziata, Ludovica Verde, Vincenzo D’Orsi, Massimiliano Caprio, Stefania Gorini, Silvia Savastano, Annamaria Colao, Giovanna Muscogiuri, Luigi Barrea

“…For this reason, the present study aimed to evaluate the effects of supplementation with 8 g per day of essential amino acids (EAAs) on these parameters. …”
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Effect of different dietary oil sources on the performance, egg quality and antioxidant capacity during the late laying period by Mengmeng Xu, Le Liu, Zongze Fan, Lizhu Niu, Wenxi Ning, He Cheng, Mengyun Li, Wenying Huo, Pan Zhou, Hongyu Deng, Wen Chen, Long Che

“…A total of 360 70-week-old Jinghong laying hens were randomly assigned to four groups of six replicates each, with 15 chickens per replicate. Diets with linseed oil to soybean oil ratios of 3:0 (T1), 2:1 (T2), 1:2 (T3), and 0:3 (T4) were fed for 4 weeks. …”
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Association between neutrophil-to-eosinophil ratio and efficacy outcomes with avelumab plus axitinib or sunitinib in patients with advanced renal cell carcinoma: post hoc analyses... by Brian Rini, Mariangela Mariani, Alessandra di Pietro, Paul Nathan, Christian Kollmannsberger, Marc-Oliver Grimm, Martin H Voss, Bradley A McGregor, Mehmet A Bilen, Yoshihiko Tomita, Bo Huang, Robert Amezquita, Matthew Tucker, Yu-Wei Chen

“…Objective We report post hoc analyses of efficacy with first-line avelumab plus axitinib or sunitinib according to baseline neutrophil-to-eosinophil ratio (NER) in patients with advanced renal cell carcinoma (aRCC) from the JAVELIN Renal 101 phase 3 trial.Methods and analysis Progression-free survival (PFS), overall survival (OS) and objective response per baseline NER were analysed in the overall population and in patients with programmed death ligand 1 (PD-L1+) tumours. …”
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Ambulance attendances involving personality disorder – investigation of crisis-driven re-attendances for mental health, alcohol and other drug, and suicide-related events by JH Broadbear, RP Ogeil, M McGrath, DS Scott, Z Nehme, F Moayeri, D Lubman, S Rao

“…Conclusions: Two-thirds of service users noted to have personality disorder required ambulance services three or more times per year, highlighting the need for evidence-based alternatives to reduce the incidence of mental health crises and reliance on emergency services. …”
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Perioperative management for people with chronic kidney disease receiving dialysis undergoing major surgery: a protocol for a scoping review by Paul E Ronksley, Matthew James, Janine F Farragher, Brenda R Hemmelgarn, Shannon M Ruzycki, Maoliosa Donald, Tyrone G Harrison, Connor O'Rielly, Deirdre McCaughey, Kelly B Zarnke

“…We describe a protocol for a scoping review of the literature to identify existing perioperative strategies, protocols, pathways and interventions for people with CKD G5D undergoing major surgery.Methods and analysis We will conduct a scoping review in accordance with the Joanna Briggs Institute methodology and report per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews. …”
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Synthesis of Nanocrystalline Mn-Doped Bi₂Te₃ Thin Films via Magnetron Sputtering by Joshua Bibby, Angadjit Singh, Emily Heppell, Jack Bollard, Barat Achinuq, Sarah J. Haigh, Gerrit van der Laan, Thorsten Hesjedal

“…Intriguingly, a decrease in magnetic moment per Mn was observed with increasing Mn concentration, which is consistent with the formation of the intrinsic magnetic topological insulator <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>MnBi</mi><mn>2</mn></msub><msub><mi>Te</mi><mn>4</mn></msub></mrow></semantics></math></inline-formula>.…”
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Impact of Economic Agglomeration on Carbon Emission Intensity and Its Spatial Spillover Effect: A Case Study of Guangdong Province, China by Qian Xu, Junyi Li, Ziqing Lin, Shuhuang Wu, Ying Yang, Zhixin Lu, Yingjie Xu, Lisi Zha

“…The spatial spillover effect of the openness degree on carbon emission intensity was positive, while GDP per capita and industrial structure had negative effects. …”
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Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients by Novaes-Gaeta Ludmila N., Moraes Mariele C., Katayama Keyla Y., Sangaletti Carine T., Irigoyen Maria Claudia, Freitas Sarah, Viana Ariane, de Angelis Katia, Caldini Elia G., Lopes Heno F.

“…Study participants received placebo capsules for 4 weeks, then fruit extract capsules (blueberry, cranberry and pomegranate), one capsule of each per day for 4 weeks. Blood pressure was measured at baseline, after the use of placebo and antioxidant capsules. …”
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Multiple use of preservative-free single dose unit dexamethasone 0.1% eye drops is safe within 24 hours by Marco Rossi, Michael A Thiel, Frank Bochmann, Philipp B Baenninger, Claude Kaufmann, Fabienne C Fierz, Silvan Locher, Lucas Bachmann, Irena Mitrovic, Jeremy P Howell

“…We investigated whether repeated use of dexamethasone 0.1% SDUs in the same patient increases the bacterial contamination rate.Methods We prospectively enrolled patients scheduled for inpatient corneal and glaucoma surgery receiving dexamethasone 0.1% SDU four times per day from the same vial. To assess contamination rates, one drop from the vial was cultured immediately after opening the SDU (t0), 10 hours later after four drop applications (t10) and 24 hours after opening without further drop applications (t24). …”
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Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China by Haoling Tang, Zhiwei Chen, Tianquan Huang, Pingping Yu, Qiao Tang, Yue Qiu, Yunling Xue, Jing Tang, Nan Cai, Hong Ren, Mingli Peng, Peng Hu

“…Forty‐three symptoms were identified during SARS‐CoV‐2 infection (11 symptoms per individual). The common symptoms were fever, cough, headache, phlegm production, and fatigue (60.67%–83.29%). …”
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Pooled safety analysis of two phase 3 studies investigating trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer by Julien Taieb, Marwan Fakih, Gabor Liposits, Gerald W. Prager, Eric Van Cutsem, Fortunato Ciardiello, Nadia Amellal, Elizabeth Calleja, Mei Liu, Lucas Roby, Josep Tabernero, Thierry André

“…Treatment-emergent adverse events (TEAEs) in SOLSTICE and SUNLIGHT were graded per Common Terminology Criteria for Adverse Events versions 4.03 and 5.0, respectively. …”
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N-Butyl-2-Cyanoacrylate Adhesive Versus Absorbable Tacks in Laparoscopic Groin Hernia Repair: A Multicenter Randomized Clinical Trial by Clayton C. Petro, MD, Benjamin K. Poulose, MD, Michael J. Rosen, MD, Alfredo M. Carbonell, II, DO, Adel G. El-Ghazzawy, MD, Jeremy A. Warren, MD, Emanuele Lo Menzo, MD, Ajita S. Prabhu, MD, David M. Krpata, MD, Samuel Szomstein, MD, Vimal Narula, MD, Crystal F. Totten, MD, Kelly R. Haisley, MD, Andrew C. Bernard, MD, Henrik O. Berdel, MD, Jessica K. Reynolds, MD, Zachary D. Warriner, MD, John S. Roth, MD

“…The difference in VAS improvement at 6 months with NB2C adhesive was not inferior to absorbable tacks in intention-to-treat and per-protocol analyses, respectively (0.25 [95% CI, −0.33 to 0.82]; P = 0.013; 0.22 [95% CI, −0.36 to 0.80], noninferiority P = 0.011). …”
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The economic burden of breast cancer in western Iran: a cross-sectional cost-of-illness study by Banafsheh Darvishi Teli, Meysam Behzadifar, Mania Beiranvand, Aziz Rezapour, Seyed Jafar Ehsanzadeh, Samad Azari, Ahad Bakhtiari, Payam Haghighatfard, Mariano Martini, Maryam Saran, Masoud Behzadifar

“…The total economic burden of breast cancer was estimated at $5,394,409.13, with a mean of $10,275.07 per patient. Direct medical costs comprised 70.2% of the total expenses, primarily attributed to hospitalization, chemotherapy, and laboratory tests. …”
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Birth preparedness and complication readiness assessment among antenatal and postnatal mothers at government hospital, in urban Bengaluru by Sangeetha M.D, Jagadish Ganagi, Darshan H.S, Neha Annet Joy, Akarsh KR

“…The maternal mortality ratio (MMR) of Karnataka is 92 per 100,000 live births in SRS 2016-18. Since Karnataka had the highest MMR ratio among the southern states of India the present study was thus conducted to determine the BPACR among antenatal and postnatal women and assess the factors related to it. …”
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Association between beta‐blocker atenolol use and prostate cancer upgrading in active surveillance1 by Ali H. Zahalka, Ethan Fram, Evan Garden, Lauren Howard, Emily Wiggins, Mustufa Babar, Jay Annam, Allison Reagan, Benjamin Eilender, Amanda deHoedt, Stephen J. Freedland, Ash Tewari, Kara L. Watts

“…Cox proportional hazard regression models were used to determine the associations between atenolol use and risk of upgrading with time, on a per‐examination basis. Results A total of 467 men with initial GG ≤ 2 were included. …”
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Effects of fermented Artemisia annua on the intestinal microbiota and metabolites of Hu lambs with naturally infected with Eimeria spp. by Shuaiqi Liu, Shuaiqi Liu, Shuaiqi Liu, Shiheng Li, Shiheng Li, Shiheng Li, Shunli Lu, Shunli Lu, Shunli Lu, Mingfan Yang, Manyu Liu, Manyu Liu, Manyu Liu, Juanfeng Li, Juanfeng Li, Juanfeng Li, Senyang Li, Senyang Li, Senyang Li, Fuchun Jian, Fuchun Jian, Fuchun Jian

“…Chinese herbal medicines are investigated as alternative methods for controlling coccidian infections.MethodsIn this study, the effect of fermented Artemisia annua (FA) on oocysts per gram (OPG), average daily gain (ADG), and expression of inflammatory factors were investigated in lambs that were naturally infected with coccidia.ResultsThe results showed that the FA had similar anti-coccidiosis effect to the original drug, while the FA demonstrated a more significant effect on weight gain, and a better ability to reduce the inflammatory response compared to the unfermented drug during the treatment period (P &lt; 0.05). …”
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Heavy slow resistance training, radial extracorporeal shock wave therapy or advice for patients with tennis elbow in the Norwegian secondary care: a randomised controlled feasibili... by Jens Ivar Brox, Marianne Bakke Johnsen, Cecilie Roe, Aasne Fenne Hoksrud, Håkon Sveinall, Kaia B Engebretsen

“…An ancillary aim was to describe within-group changes in the secondary outcome measures (patient-reported and performance-based).Design A single-centre, three-armed, randomised controlled feasibility trial with a parallel design, with follow-up after 3 and 6 months.Setting Participants were recruited from the outpatient clinic at Oslo University Hospital.Participants Patients with lateral epicondylalgia, commonly known as tennis elbow.Interventions Participants were randomised in a 1:1:1 ratio to heavy slow resistance training, radial extracorporeal shock wave therapy or information and advice.Main outcome measures Feasibility was assessed according to a priori criteria for success.Results In total, 89 patients were screened for eligibility, and 69 (78%) patients were eligible for randomisation. 60 (92%) participants were randomised which gave a recruitment rate of 3.4 per month (against an a priori success cut-off of 3.75). …”
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