Canadian healthcare capacity gaps for disease-modifying treatment in Huntington’s disease: a survey of current practice and modelling of future needs by Sylvain Chouinard, Blair R Leavitt, Angèle Bénard, Nathalie Budd, Jennifer W Wu, Kerrie Schoffer

“…The average national incremental nursing, room, neurologist and social worker support required to provide IT DMT to all eligible patients is 0.73, 0.36, 0.30 and 0.21 FTE per HD centre, respectively. At peak demand, current capacity would support the treatment of 6% of IT DMT-eligible patients. …”
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Characterizing the Flow and Interaction of Microbubbles in a 2D Capillary Network for Targeted Drug Delivery: A Simulation Study by Sadegh Shurche, Akram Shahidani, Roghaye Bodaghi Hossein Abadi

“…Materials and Methods: We designed the capillary network based on the tree pattern employed in quantitative studies per Murray’s minimum work rule and the cardiovascular network to simulate the hemodynamics of the vessels. …”
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Biomorphological and useful agronomic traits of the hexaploid winter triticale cultivar ‘Bilinda’ approved for cultivation in the Northwestern Region of the Russian Federation by L. P. Bekish, V. A. Uspenskaja, T. I. Peneva, N. N. Chikida

“…‘Bilinda’ significantly exceeded the reference ‘Kornet’ in grain yield (+1.04 t/ha), number of grains per ear (+32.3 pcs), and 1000 grain weight (+7.7 g), and in addition demonstrated higher winter hardiness than the reference (up to 98%). …”
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Experiencias incipientes de inventarios de emisiones de gases de efecto invernadero en el ámbito local en Costa Rica by Daniela García Sánchez, Jessie Vega Méndez, Laura Mora Mora

“…El sector transporte es la principal fuente, excepto en Belén, donde fue superado por el sector de energía para uso industrial. Los datos per cápita, muestran que pequeños distritos pueden presentar niveles de emisión por persona superiores a los de cantones urbanos. …”
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Barriers to Physical Activity in East Harlem, New York by Ashley M. Fox, Devin M. Mann, Michelle A. Ramos, Lawrence C. Kleinman, Carol R. Horowitz

“…Physical activity was measured in two ways: respondents were classified as having met the weekly recommended target of 2.5 hours of moderate physical activity (walking) per week (or not) and reporting having engaged in at least one recreational physical activity (or not). …”
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Benefit from regular versus leakage-related exchange of voice prostheses in patients post-laryngectomy considering complication rates and patient satisfaction feedback—a randomized... by Michał Żurek, Małgorzata Czesak, Daniel Majszyk, Anna Rzepakowska

“…The secondary outcome measures were the mean number of exchanges per year and patient satisfaction.ResultsThirty-six patients continued the study according to the protocol, with 16 in REA and 20 in LEA. …”
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Interaction of the gastroenterologist and psychiatrist at management of patient with functional disorder of gastro-intestinal tract by V. T. Ivashkin, Ye. A. Poluektova, A. G. Beniashvili

“…Taking into account patient’s complaints (bloating and abdominal pain relieved after defecation, frequent stool up to 3–5 times per day, incidental imperative urgency to defecation and feeling of incomplete defecation), and long-term benign course of disease, absence of organic changes, according to results of laboratory tests and instrumental investigations irritable bowel syndrome has been diagnosed. …”
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Firearms control as an element of criminological security in the concept of transitional justice for Ukraine by Yu. V. Orlov, A. M. Yashchenko

“…The article proposes a criminological model for establishing control over firearms circulation which provides for: 1) preservation of the existing legal regime of firearms circulation for civilians until the end of the armed conflict and the legal regime of martial law; after the lifting of martial law, a balanced legalisation of civilian (short-barreled) weapons with strict control, verification and constant monitoring is required; 2) for military personnel (including those discharged from service): a) a special type of exemption from criminal liability under Articles 263 and 410 (regarding misappropriation of firearms, ammunition, explosives or other munitions) of the Criminal Code of Ukraine, subject to presentation for inspection, registration and issuance of a permit (de lege ferenda); b) obtaining a permit (de lege ferenda) for storage of firearms (in the amount of no more than one unit per person) and ammunition (in the amount of no more than 60 pieces); 3) criminal liability for violation of the conditions of the permit to keep and carry firearms. …”
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Snapshot of health-related behaviours in adults living with disabilities 1 year into the COVID-19 pandemic: a cross-sectional survey study by Syeda F Hussain, Nikki Heinze, Claire L Castle, Lauren R Godier-McBard, Theofilos Kempapidis, Renata S M Gomes

“…Although the majority in both groups reported exercising three to four times per week and eating what they should, those with disabilities were more likely to eat less than they should, not exercise at all and to have been self-isolating for over 6 months than participants with no disabilities.Conclusions The data in this study present some key differences between the two groups, with those living with disabilities being more likely to report that they had been self-isolating for prolonged periods of time, not exercising at all, and not eating as much as they should . …”
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Cost-Effectiveness of the CNIC-Polypill Strategy Compared With Separate Monocomponents in Secondary Prevention of Cardiovascular and Cerebrovascular Disease in Portugal: The MERCUR... by Carlos Aguiar, Francisco Araujo, Gabriel Rubio-Mercade, David Carcedo, Silvia Paz, Jose María Castellano, Valentín Fuster

“…Outcomes were costs (estimated in 2020 euros) per life-year (LY) and quality-adjusted LY (QALY) gained. …”
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Intersection between individual, household, environmental and system level factors in defining risk and resilience for children in Kenya's ASAL: A qualitative study. by Esther Jebor Chongwo, Barack Aoko, Martha Kaniala, Moses Esala, Phillis Magoma, Eunice Njoroge, Susan Nyamanya, Joyce Marangu, Anil Khamis, John Ng'asike, Anja C Huizink, Amina Abubakar

“…Purposive and snowballing techniques were used to recruit 11 key informants per site with varied levels of involvement in early childhood development and primary caregivers. …”
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Overcoming the Socio-Economic Challenges to Good Governance: Streamlining Cooperative Governance Model by Bhekabantu Alson Ntshangase, Kaizer Raseane Makole, Steven Kayambazinthu Msosa

“…Thus, to ensure best practices, parliamentary oversight structures and responsible departments, like the National Treasury, should build checks and balances in their institutional mechanisms that strive to streamline good cooperative governance practices and accountability measures as per constitutional prescripts to ensure that basic services are effectively and sufficiently rendered across cooperative governance spheres. …”
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Genetic Components Derived Parameters and Heterosis in Okra under Saudi Arabia Conditions by Mohamed F. M. Abdelkader, Mohamed H. Mahmoud, Mohamed Z. Diyasty, Noha A. Sukar, Maged I. Farag, Nesma N. I. Mohamed, Yasser A. M. A. Salama, Mohamed A. Abdein

“…The superior crosses identified through heterosis analysis were Egyptian Balady × Line 4.1.18 (30.8 ton/ha), Line 4.1.18 × Egyptian Balady (29.8 ton/ha), Dwarf Green Long Pod × Line 4.1.18 (28.3 ton/ha), and Egyptian Balady × Dwarf Green Long Pod (27.6 ton/ha) as these crosses had high performance as well as significant and higher estimates of heterobeltiosis for fruit yield per plant and yield attributing other characters.…”
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Epidemiology and spatiotemporal analysis of acute hemorrhagic conjunctivitis in Zhejiang province, China (2004–2023) by Wanwan Sun, Yijuan Chen, Shuwen Qin, Ziping Miao

“…The epidemiological characteristics of AHC outbreaks in the same period in Zhejiang province were also compared.ResultsA total of 52,119 AHC cases were reported in Zhejiang province, yielding an average incidence rate of 5.37 per 100,000. No fatalities were reported. The average age of those affected was 25.44 ± 4.37 years, with the highest incidence (16.70%) among individuals aged between 10 and 19 years. …”
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Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease by Heidi Borgeraas, Elin Strand, Eva Ringdal Pedersen, Jutta Dierkes, Per Magne Ueland, Reinhard Seifert, Eirik Rebnord Wilberg, Pavol Bohov, Rolf K. Berge, Dennis W. T. Nilsen, Ottar Nygård

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Time to breastfeeding cessation and its predictors among mothers of index children aged 2–3 years in Bedele Town, Southwest Ethiopia: a community-based retrospective follow-up stud... by Gebiso Roba Debele, Fedasa Tesfa, Dereje Tsegaye

“…The Weibull proportional hazard model was used to identify predictors for time to breastfeeding cessation.Result The overall incidence of early cessation of breastfeeding was found to be 11.05 per 1000 person-months of the follow-up period. …”
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Screening, diagnosis, treatment and outcomes of developmental dysplasia of the hip in Brazilian population: a scoping review by Emily Schaeffer, Patricia Moreno Grangeiro, Patrícia Eduarda Conrado Martins Rocha Jaleca, Sheila Lam, Sana Arora, Daniel Frank Liggio

“…Reported prevalence rates ranged from 0.75 to 56.4 cases per 1000 children. No study examined the effectiveness of specific screening programmes or compared their outcomes. …”
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ANÁLISIS DE LAS RELACIONES COMERCIALES ENTRE IBEROAMÉRICA Y EL CARIBE Y LA UNIÓN EUROPEA (1992-2003) by Eduardo Cuenca García, José Antonio Rodríguez Martín

“…Las ca rac te r ís ti cas ge ne ra les, la in ten si dad de los mis mos y su con cen tra ción en zo nas de ter mi na das se han abor da do uti li zan do una se rie de in di ca do res que per mi ten ob te ner con clu sio nes de es tas trans for ma cio nes.…”
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Genome-wide discovery of InDels and validation of PCR-Based InDel markers for earliness in a RIL population and genotypes of lentil (Lens culinaris Medik.). by K M Shivaprasad, Muraleedhar Aski, Gyan Prakash Mishra, Subodh Kumar Sinha, Soma Gupta, Dwijesh C Mishra, Amit Kumar Singh, Akanksha Singh, Kuldeep Tripathi, Ranjeet Ranjan Kumar, Atul Kumar, Shiv Kumar, Harsh K Dikshit

“…Finally, 734,716 novel InDels were identified, which is nearly one InDel per 5,096 bp of lentil genome. Furthermore, 74.94% of InDels were within the intergenic region and 99.45% displayed modifier effects. …”
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A cost-utility analysis of adding SGLT2 inhibitors for the management of type 2 diabetes with chronic kidney disease in Thailand by Natthakan Chitpim, Pattara Leelahavarong, Juthamas Prawjaeng, Sakditat Ittiphisit, Varalak Srinonprasert, Tanawan Kongmalai

“…Empagliflozin was cost-effective at a WTP threshold of $4,336 per QALY ($3,386/QALY), while dapagliflozin ($5,783/QALY) and canagliflozin ($4,591/QALY) required price reductions. …”
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