A Curious Case of Rowell Syndrome by Seetharaman Venugopalan Iyer, Delnaz Palsetia, Alka A. Subramanyam

“…Besides the dermatological manifestations, Rowell syndrome can also have significant neuropsychiatric symptoms such as cognitive dysfunction, mood disorders, psychosis, seizures and peripheral neuropathy in some patients. Diagnosis and subsequent management of such a rare syndrome with uncommon presentations can be challenging. …”
Get full text

Neurosarcoidosis camouflaging as partial miller: Fisher syndrome by B N Shiva Prasad, Subramanian Ramaswamy, Aumir Moin, Srinivas Nalloor

“…Neurological involvement in sarcoidosis has varied presentations. Peripheral neuropathy is one of them. Symmetrical axonal type sensory-motor polyneuropathy is the most common form; focal and multifocal neuropathy, polyradiculopathy, and vascular neuropathy are among the others. …”
Get full text

Challenges faced during antitubercular therapy by B. K. Likhitha, Shreeshail Anjutagi, Keertivardhan D. Kulkarni, Madhav Mahawar

“…The patient presented with peripheral neuropathy, deranged liver function, elevated uric acid levels, gastritis, and psychological distress during the treatment period. …”
Get full text

Relapsing Hepatitis A Infection with Immunological Sequelae by Deborah J. Cook, Robert H. Riddell, Max A. Chernesky, Bruno J. Salena, Renata Slapsys

“…A patient with persistent anti-hepatitis A virus (HAV) lgM following icteric hepatitis A, vasculitis, arthritis and peripheral neuropathy is reported. The clinical, biochemical and serological features of re lapsing hepatitis A arc described.…”
Get full text

Yersiniosis and acute secondary axonal sensorimotor polyneuropathy: a case report by A. Daškevičiūtė, R. Mameniškienė

“…There were no other causes of peripheral neuropathy detected and we assume that yersiniosis was the cause of acute axonal sensorimotor polyneuropathylanguage most frequently inhibited EDs in patients with focal epilepsy and reading in an unknown language had the same effect on patients with generalized epilepsy. …”
Get full text

The Need for Improved Management of Painful Diabetic Neuropathy in Primary Care by Teresa Sobhy

“…The provision of care for patients with type II diabetes in primary care must involve assessing patients for peripheral neuropathy of the feet. Objectives. This paper will demonstrate that painful diabetic neuropathy (PDN) is poorly assessed for and treated in primary care. …”
Get full text

Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature by Zahra A. Natsha, Islam A. Hamarsheh, Rawan S. Utt, Bassam Abu Alrob, Adnan A. Wahdan

“…Here, we report the second documented case of KD in Palestine diagnosed in a 28-year-old male patient who presented with lymphadenopathy and increased serum immunoglobulin E and G (IgE and IgG) associated with intermittent abdominal pain, generalised fatigue, hepatomegaly, cardiomyopathy, reactive airway disease, peripheral vasculopathy, peripheral neuropathy, and focal segmental glomerulosclerosis. …”
Get full text

Sensory-Motor Polyneuropathy and Digital Ischemia: A Rare Presentation of Granulomatosis with Polyangiitis by Wasundara Wathurapatha, B. G. A. Rathnamali, Upul Dissanayake

“…This case highlights the importance of suspecting GPA in a patient presenting with sensorimotor polyneuropathy and/or digital ischemia even in the absence of more classic presenting features and underlies the necessity of accurate differential diagnosis in evaluating a case of peripheral neuropathy.…”
Get full text

A Presentation of Cerebritis Secondary to Granulomatosis with Polyangiitis (Wegener) by James Norman, Ira Pande, Timothy Taylor, Bruno Gran

“…Neurological manifestations of GPA are common, most frequently as a peripheral neuropathy. Cerebritis as a principal presentation is extremely rare. …”
Get full text

Isolation of Intact Mitochondria From Drosophila melanogaster and Assessment of Mitochondrial Respiratory Capacity Using Seahorse Analyzer by Christopher Groen, Anthony Windebank

“…Neurodegenerative disorders such as chemotherapy-induced peripheral neuropathy (CIPN) often exhibit damaged mitochondria or reduced mitochondrial respiratory capacity. …”
Get full text

A Case of Effective Mepolizumab Induction Therapy for Severe Eosinophilic Granulomatosis with Polyangiitis Diagnosed by Eosinophilic Cholecystitis and Interstitial Nephritis by Keita Hattori, Yuri Teramachi, Yoshinori Kobayashi, Takeshi Ito, Takatoshi Morinaga, Hirohumi Tamai, Yoshihiro Yamamoto

“…A 66-year-old man with a history of bronchial asthma and sinusitis was admitted with cholecystitis and peripheral neuropathy. The histopathological findings of the gallbladder revealed necrotic vasculitis and granulomatous inflammation with marked eosinophilic infiltration. …”
Get full text

Vitamin B12 Deficiency due to Chlorofluorocarbon: A Case Report by Hemlata Bhaskar, Rekha Chaudhary

“…Deficiency of vitamin B12 clinically manifests as excessive daytime fatigue, memory difficulties, encephalopathy, myelopathy, peripheral neuropathy, and optic neuropathy. In occupational medicine, vitamin B12 deficiency has been reported with exposure to nitrous oxide in health care workers. …”
Get full text

Hepatitis C Virus, Cryoglobulinemia, and Kidney: Novel Evidence by Fabrizio Fabrizi

“…Mixed cyoglobulinemia is a systemic vasculitis primarily mediated by immune complexes; it is characterized by variable organ involvement including skin lesions, chronic hepatitis, glomerulonephritis, peripheral neuropathy, and arthralgias. The most frequent HCV-associated nephropathy is type I membranoproliferative glomerulonephritis, usually in the context of type II mixed cryoglobulinemia. …”
Get full text

Brain magnetic resonance imaging findings in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): A case-based review by Maria Veatriki Christodoulou, MD, MSc, Nikoletta Anagnostou, MD, MSc, Anastasia K. Zikou, MD, PhD

“…Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is a rare autosomal recessive disorder, manifesting with gastrointestinal dysmotility, cachexia, ptosis and peripheral neuropathy. Diffuse leukoencephalopathy in brain MRI is a hallmark of MNGIE. …”
Get full text

BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Cent... by Lekhjung Thapa, P. V. S. Rana

“…In this cross-sectional study, we included 50 adult overweight and obese nondiabetic volunteers without features of peripheral neuropathy and 50 healthy volunteers to determine the normative nerve conduction data. …”
Get full text

Muscarinic acetylcholine type 1 receptor antagonism activates TRPM3 to augment mitochondrial function and drive axonal repair in adult sensory neurons by Sanjana Chauhan, Darrell R. Smith, Shiva Shariati-Ievari, Abhay Srivastava, Sanjiv Dhingra, Michel Aliani, Paul Fernyhough

“…Objective: Antagonism of the muscarinic acetylcholine type 1 receptor (M1R) promotes sensory axon repair and is protective in peripheral neuropathy, however, the mechanism remains elusive. …”
Get full text

Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus by Lisha He, Han Wang, Chengjuan Gu, Xinhui He, Linhua Zhao, Xiaolin Tong

“…Here, we reviewed the scientific evidence underpinning the use of blood circulation activating drugs to prevent and treat DM-induced microvascular complications, including diabetic nephropathy (DN), diabetic peripheral neuropathy (DPN), and diabetic retinopathy (DR). …”
Get full text

P-ANCA Systemic Vasculitis Induced by Brucellosis in an Elderly Male Patient by Mohammed Cheikh, Abdulrahman Kabli, Esraa Sendi, Hani Almoallim

“…All symptoms improved from the third month of follow-up except weakness from peripheral neuropathy with normalization of P-ANCA titer. …”
Get full text

Expert Opinion on Fixed Dose Combination of Dapagliflozin Plus Sitagliptin for Unmet Cardiovascular Benefits in Type 2 Diabetes Mellitus by Soumitra Ray, J Ezhilan, Rajiv Karnik, Ashish Prasad, Rajashree Dhar

“…Abstract Type 2 diabetes mellitus (T2DM) is known to be associated with macrovascular (coronary heart disease, stroke, and peripheral arterial disease) and microvascular complications (diabetic kidney disease, retinopathy, and peripheral neuropathy). The coexistence of T2DM with established/risk of atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), or chronic kidney disease confers a poor prognosis, and management can be challenging. …”
Get full text

Syringomyelia with Chiari I Malformation Presenting as Hip Charcot Arthropathy: A Case Report and Literature Review by Roya Memarpour, Basheer Tashtoush, Lydia Issac, Fernando Gonzalez-Ibarra

“…It is seen most commonly in the foot and ankle secondary to peripheral neuropathy associated with diabetes mellitus. …”
Get full text