Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice by Chu X, Ge Y, Geng C, Cao P, Wei P, Fu B, Deng Z, Li Y, Zhao G

“…Xiaoqi Chu,1,2,* Yusong Ge,3,* Chao Geng,1,2 Peipei Cao,1,2 Penghu Wei,2 Bin Fu,2 Zihao Deng,4 Yuhao Li,5,6 Guoguang Zhao2,7 1Optometry Institute, School of Medicine Nankai University, Tianjin, People’s Republic of China; 2Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China; 3Department of Neurology, The Second Hospital of Dalian Medical University, Dalian, People’s Republic of China; 4Cancer Center, Capital Medical University, Beijing, People’s Republic of China; 5Central Laboratory, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China; 6Department of Pathology, School of Medicine Nankai University, Tianjin, People’s Republic of China; 7National Medical Center for Neurological Diseases, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guoguang Zhao, Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China, Email ggzhao@vip.sina.com Yuhao Li, Central Laboratory, Xuanwu Hospital Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, People’s Republic of China, Email liyuhao@xwhosp.orgPurpose: Lactate, previously considered a metabolic waste product, has been shown to have neuroprotective potential. …”
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Cooperative twinning behavior leads to superior mechanical properties in a coherently precipitated high-entropy alloy by Shuai Yuan, Xinghao Du, Dezheng liu, Chenxi Yuan, Zeyu Xing, Jinyu Zhang, Hechuan Ma, Shijun Zhao, Wanpeng Li, Baolin Wu, Jun Sun

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Aβ-Induced Repressor Element 1-Silencing Transcription Factor (REST) Gene Delivery Suppresses Activation of Microglia-Like BV-2 Cells by Tongya Yu, Hui Quan, Yuzhen Xu, Yunxiao Dou, Feihong Wang, Yingying Lin, Xue Qi, Yanxin Zhao, Xueyuan Liu

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Pectin‐decorated selenium nanoparticles as a nanocarrier of curcumin to achieve enhanced physicochemical and biological properties by Yan Wu, Hong Liu, Zhihua Li, Dongye Huang, Lizheng Nong, Zhengxing Ning, Zhizhong Hu, Chunping Xu, Jing‐Kun Yan

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A cell-penetrating bispecific antibody suppresses hepatitis B virus replication and secretion by Chongwei Xie, Bing Zhou, Da Yao, Xin Wang, Lihong Zhong, Chuanghua Qiu, Junfang Zhang

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FGF21 Is Associated with Acanthosis Nigricans in Obese Patients by Yueye Huang, Jie Yang, Yan Li, Jiaqi Chen, Kexiu Song, Xingchun Wang, Le Bu, Xiaoyun Cheng, Jiying Wang, Shen Qu

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Phages adapt to recognize an O-antigen polysaccharide site by mutating the “backup” tail protein ORF59, enabling reinfection of phage-resistant Klebsiella pneumoniae by Ping Li, Wenjie Ma, Jun Cheng, Cuixing Zhan, Hongzhou Lu, Jiayin Shen, Xin Zhou

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Triglyceride-glucose index is associated with microcirculatory resistance in patients with type 2 diabetes and STEMI undergoing primary PCI by Guoyu Wang, Cen Xu, Jian Wang, Zhimei Teng, Xiang Sha, Kai Xu, Ruzhu Wang, Li Zhu

“…We consecutively recruited 168 patients with T2DM and STEMI who underwent primary percutaneous coronary intervention (pPCI) at Taizhou People’s Hospital from January 2022 to December 2023. …”
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Targeted inhibition of ferroptosis in bone marrow mesenchymal stem cells by engineered exosomes alleviates bone loss in smoking-related osteoporosis by Yao Wang, Lin Sun, Zhenglin Dong, Tianyu Zhang, Leining Wang, Yihui Cao, Hui Xu, Chenglei Liu, Bo Chen

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Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity by Wenhui Mo, Chengfen Wang, Jingjing Li, Kan Chen, Yujing Xia, Sainan Li, Ling Xu, Xiya Lu, Wenwen Wang, Chuanyong Guo

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Impact of Abdominal Obesity on Thyroid Auto-Antibody Positivity: Abdominal Obesity Can Enhance the Risk of Thyroid Autoimmunity in Men by Jazyra Zynat, Suli Li, Yanrong Ma, Li Han, Fuhui Ma, Yuyuan Zhang, Bei Xing, Xinling Wang, Yanying Guo

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RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis by Qin Y, Liao S, Sun J, Ye H, Li J, Pan J, He J, Xia Z, Shao Y

“…Yuting Qin,1,* Shuanglin Liao,1,* Jianbo Sun,2 Huiyun Ye,1 Jiafu Li,1 Jiahui Pan,1 Junbing He,3 Zhengyuan Xia,4,5 Yiming Shao1,6 1Dongguan Key Laboratory of Sepsis Translational Medicine, The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 2Dongguan Key Laboratory of Chronic Inflammatory Diseases, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 3The Key Laboratory of Organ Dysfunction and Protection Translational Medicine, Jieyang Medical Research Center, Jieyang People’s Hospital, Jieyang, Guangdong, People’s Republic of China; 4Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China; 5State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; 6The Key Laboratory of Sepsis Translational Medicine, Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yiming Shao, Dongguan Key Laboratory of Sepsis Translational Medicine, the Intensive Care Unit,The First Dongguan Affiliated Hospital, Guangdong Medical University, Jiaoping Road 42, Tangxia Town, Dongguan, Guangdong Province, 523710, People’s Republic of China, Tel +86 18826690188, Email sym@gdmu.edu.cn Zhengyuan Xia, Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China, Tel +852-68798794, Email zyxia@hku.hkAbstract: Reversion inducing cysteine rich protein with kazal motifs (RECK), a Kazal motif-containing protein, regulates pro-inflammatory cytokines production, migration of inflammatory cells, vascular endothelial growth factor (VEGF) and Wnt pathways and plays critical roles in septic inflammatory storms and vascular endothelial dysfunction. …”
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Mechanisms of nitrogen and phosphorus release from heavily polluted coastal sediments and identification of influencing factor by Nana Hu, Yanqing Sheng, Qi Tang, Xiaozhu Liu

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Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review by Huimeng Li, Liying Yang, Xiqiang Sun, Zhuquan Wang, Shuangwei Qin, Chengcheng Li, Gongwu Liu, Fengming Xie, Weiwei Gao

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Striking a balance between aesthetics and safety: a comparative study on the maternal and neonatal outcomes of mini-incision cesarean section by ChunLan Yuan, ShiMei He, WenQian Jian, MeiRong He, HuiFang Huang, JianChun Huang, MeiPing He, KaiSun Zhao

“…Methods A total of 99 pregnant women with full-term singleton pregnancies, who delivered at the Second Nanning People's Hospital from January 2024 to September 2024, were enrolled in this study. …”
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Correlation between the Frequency of Th17 Cell and the Expression of MicroRNA-206 in Patients with Dermatomyositis by Xinyi Tang, Xinyu Tian, Yue Zhang, Wei Wu, Jie Tian, Ke Rui, Jia Tong, Liwei Lu, Huaxi Xu, Shengjun Wang

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Concentrated growth factors promote epithelization in the mastoid obliteration after canal wall down mastoidectomy by Mengyi Liu, Lue Zhang, Quanming Zhang, Nan Zeng, Shuo Li, Shuyue Guo, Yaqin Zhao, Mingxing Tang, Qiong Yang

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Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain by Hao-Ming Xu, Hong-Li Huang, You-Lian Zhou, Hai-Lan Zhao, Jing Xu, Di-Wen Shou, Yan-Di Liu, Yong-Jian Zhou, Yu-Qiang Nie

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Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice by Ying Huang, Haiying Hu, Ling Liu, Jing Ye, Zhen Wang, Bin Que, Wenjing Liu, Ying Shi, Tao Zeng, Lei Shi, Qingwei Ji, Chao Chang, Yingzhong Lin

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Restoration of Foveal Bulge after Resolution of Diabetic Macular Edema with Coexisting Serous Retinal Detachment by Yijun Hu, Qiaowei Wu, Baoyi Liu, Manqing Huang, Qingsheng Peng, Pingting Zhong, Xiaomin Zeng, Yu Xiao, Cong Li, Ying Fang, Tao Li, Honghua Yu, Xiaohong Yang

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