2-Aminothiophene Derivatives—New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity by Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Roberto Pontarolo, Julyanne Maria Saraiva de Sousa, Klinger Antonio da Franca Rodrigues, Marcus Tullius Scotti, Anuraj Nayarisseri, Pascal Marchand, Francisco Jaime Bezerra Mendonça-Junior

“…<b>Background/Objectives</b>: Leishmaniasis is one of the 20 Neglected Tropical Diseases according to the WHO, affecting approximately 12 million people in four continents, generating serious public health problems. …”
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Implementasi Data Mining untuk Deteksi Penyakit Ginjal Kronis (PGK) menggunakan K-Nearest Neighbor (KNN) dengan Backward Elimination by Ikhsan Wisnuadji Gamadarenda, Indra Waspada

“…Abstract Chronic kidney disease (CKD) is a health problem for people around the world with increasing incidence. …”
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Efficacy of Moringa oleifera Seed Husk as Adsorptive Agent for Trihalomethanes from a Water Treatment Plant in Southwestern, Nigeria by Aderonke Adetutu Okoya, Olasunkanmi Olalekan Olaiya, Abimbola Bankole Akinyele, Nnenneh Oruada Ochor

“…Moringa oleifera (MO) has found wide acceptance by many people in Nigeria who have used it for food for both humans and fauna, for health purposes, and as a coagulant for water treatment. …”
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PRACTICAL TRAINING OF OFFICERS OF THE STATE FIRE SERVICE THROUGH GAME-BASED LEARNING by V. V. Bulgakov, A. A. Lazarev, E. P. Konovalenko, T. A. Mochalova

“…It is common knowledge that lives and health of people as well as safe operation of various infrastructures depend on the high level of professionalism of the staff responsible for safety. …”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

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Snacking Behaviour and Its Determinants among College-Going Students in Coastal South India by Prasanna Mithra, Bhaskaran Unnikrishnan, Rekha Thapar, Nithin Kumar, Sharana Hegde, Anjali Mangaldas Kamat, Vaman Kulkarni, Ramesh Holla, B. B. Darshan, Kanchan Tanuj, Vasudev Guddattu, Avinash Kumar

“…Appropriate measures are needed among younger people to follow fixed eating patterns and avoid skipping of regular meals.…”
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Consumer Anthropomorphism and Happiness: Analysis of the Brand Authenticity Effect by Mehdi Khademi Gerashi, Setare Mohammadian

“…The process of anthropomorphism refers to the special desire of humans to attribute human characteristics to non-human beings, which can provide a basis for greater satisfaction. Given that people naturally tend to attribute human characteristics to beings, objects, and phenomena, and many researchers consider this tendency an essential tool for comprehending factors beyond human nature, it can serve as a foundation for enhancing customer satisfaction. …”
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Hubungan Indeks Massa Tubuh dengan Ketahanan Kardiorespirasi, Kekuatan dan Ketahanan Otot dan Fleksibilitas pada Mahasiswa Laki-Laki Jurusan Pendidikan Dokter Universitas Andalas A... by Haslan Muhaimin Lubis, Delmi Sulastri, Afriwardi .

“…This was a study observational analitic using design cross sectional study by the number of 72 people. Cardiorespiratory endurance obtained by calculating the value of bycycle ergometer test using VO2maks method astrand 6 minute cycle test, conducted measurement of height and weight, muscle strength is graded with a hand dynamometer and back strength dynamometer, muscle endurance is assessed with the bent leg sit-up, and flexibility with the sit and reach test, trunk extension, and shoulder lift. …”
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Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

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Assessing One Health integration in Somalia’s school curriculum for future pandemic preparedness by Ahmed Abdulkadir Hassan-Kadle, Aamir Muse Osman, Abas Mohamed Sharif

“…Collaborative efforts to revise curricula can bolster resilience against pandemics and promote holistic well-being, benefitting the overall well-being of people, animals, plants, and the environment. One Health impact statement This study highlights the critical need to incorporate One Health concepts into Somalia’s education system to equip future generations with the knowledge and skills necessary to address interconnected health challenges facing humans, animals, plants, and the environment. …”
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Pengaruh Pemberian Diet Tinggi Minyak Sawit terhadap Kadar Malondialdehid Darah Tikus Wistar by Maressya Silvia Eszy, Susila Sastri, Machdawaty Masri

“…<br />Kata kunci: minyak sawit, SFA, MUFA, antioxidant, ROS, MDA</p><p>Abstract<br />Palm oil is a source of fat which most widely consumed by Indonesian people. This oil contains 50% Saturated Fatty Acid (SFA), 40% Monounsaturated Fatty Acid (MUFA), 10% Polyunsaturated Fatty Acid (PUFA), antioxidant, vitamin E and beta-carotene. …”
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Effectiveness, cost-effectiveness and return on investment of individual placement and support compared with traditional vocational rehabilitation for individuals with severe menta... by Johanna Maria van Dongen, Philippe Delespaul, Frederieke Schaafsma, Jaap van Weeghel, Johannes Anema, Miljana Vukadin, Wim Zwinkels, Marcel Spijkerman, Marloes de Graaf-Zijl

“…From the societal and payer perspective, IPS was—on average—less costly and more effective than TVR and return-on-investment estimates showed that IPS was—on average—cost saving (eg, societal perspective: ∆C: −364 (95% CI −3977 to 3249); ∆E: 0.104 (95% CI 0.046 to 0.164); benefit–cost ratio: 2.1 (95% CI −14.8 to 19.1)), but the uncertainty surrounding these estimates was large.Conclusions IPS implemented through a reimbursement strategy on a nationwide scale is more effective and potentially cost-effective than TVR in people with severe mental illness receiving sickness or disability benefits. …”
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Preference for HIV testing among community residents in Yunnan Province, China: results from a discrete choice experiment by Jingwen Yang, Chenquan Qiu, Renhai Tang, Wenbin Dong, Enlong Yao, Huyunzhao Wang, Shuwen Lin, Minyang Xiao, Zuyang Zhang, Jin Niu, Liru Fu, Lijun Song, Xuehua Li, Yuhua Shi, Xiaowen Wang

“…Abstract Background The detection and early identification of people living with HIV/AIDS (PLWH) and their rapid engagement in antiretroviral treatment are indispensable for fighting HIV transmission. …”
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Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis by Jiaqi Yao, Yuhong Jiang, Pengcheng Zhang, Yifan Miao, Xiajia Wu, Hang Lei, Zhijun Xie, Yong Tian, Xianlin Zhao, Juan Li, Lv Zhu, Meihua Wan, Wenfu Tang

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The Relationship between Body Mass Index and Incident Diabetes Mellitus in Chinese Aged Population: A Cohort Study by M. L. Tang, Y. Q. Zhou, A. Q. Song, J. L. Wang, Y. P. Wan, R. Y. Xu

“…A total number of 6,911 Chinese elderly people (4,110 men and 2,801 women, aged 71±6.0 years) were included in this cohort study. …”
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Whole systems approaches to diet and healthy weight: A scoping review of reviews. by Gavin Breslin, Olujoke Fakoya, Wendy Wills, Nigel Lloyd, Charis Bontoft, Amander Wellings, Sian Harding, John Jackson, Katherine Barrett, Adam P Wagner, Lisa Miners, Honey-Anne Greco, Katherine E Brown

“…Consequently, a Whole System Approach (WSA)-which considers the many causes of obesity and shifts the focus away from individuals as points of intervention and puts an emphasis on understanding and improving the system in which people live-is required. This scoping review of reviews aims to: determine how WSAs to diet and healthy weight have been implemented and evaluated nationally and internationally; to determine what models or theories have been used to implement WSAs; describe how WSAs have been evaluated; determine if WSAs are effective; and to identify the contribution of the public and/or service users in the development of WSAs.…”
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Droplets Cas13a‐RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer by Jingsong Xu, Li Cao, Shuang Yang, Ying Jian, Yu Liu, Zhen Shen, Qian Liu, Xiang Chen, Min Li, Shun Li, Xiaolei Zuo, Min Li, Hua Wang

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Advancements in 3D printing technologies for personalized treatment of osteonecrosis of the femoral head by Tingting Chen, Lincong Luo, Jiaying Li, Jiamin Li, Tao Lin, Mingrui Liu, Hang Sang, Xinyu Hong, Jiahao Pu, Wenhua Huang

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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

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Development a glycosylated extracellular vesicle-derived miRNA Signature for early detection of esophageal squamous cell carcinoma by Jianlin Chen, Yue Zheng, Zhen Wang, Qi Gao, Kun Hao, Xiongfeng Chen, Nantian Ke, Xiang Lv, Jiamiao Weng, Yuhong Zhong, Zhixin Huang, Miao Fu, Lilan Zhao, Fan Lin, Hui Mi, Haijun Tang, Chundong Yu, Yi Huang

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