Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells by Yan Ding, Jialai Yan, Ling Huang, Jinhong Yu, Yandan Wu, Chuanlai Shen, Anning Fang

“…A broad-spectrum CD8+ T-cell epitope library containing 141 validated epitope peptides was used to universally detect HIV-1-specific CD8+ T cells via peptide-PBMC ex vivo coculture and intracellular IFN-γ staining. In 52 people with HIV-1, the number of reactive HIV-1 specific CD8+ T cells was significantly higher in the CD4+ T-cell-high patient group compared to the CD4+ T-cell-low patient group, and it correlated with the CD4+ T-cell-low patient group (<200/μL).ConclusionThis study provides a broad-spectrum CD8+ T-cell epitope library aimed at developing a T-cell-directed HIV vaccine that offers high population coverage in Northeast Asia. …”
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Histone lysine crotonylation accelerates ACSL4-mediated ferroptosis of keratinocytes via modulating autophagy in diabetic wound healing by Fengjuan Li, Haowen Ye, Lanlan Li, Qingling Chen, Xianwu Lan, Liangxiu Wu, Bin Li, Lishan Li, Chuxian Guo, Milad Ashrafizadeh, Gautam Sethi, Jun Guo, Liangyan Wu

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Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer by Yuankui Zhu, Yaxi Yang, Linghe Yue, Lei Wan, Xuqian Ma, Qing Yang, Xuan Tian, Yuguan Li, Ke Wang, Shaozhong Wei, Shaozhong Wei, Shaozhong Wei, Dianbao Zuo, Mingqian Feng, Mingqian Feng

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Multisectoral interventions for urban health in Africa: a mixed-methods systematic review by Meelan Thondoo, Ebele R. I. Mogo, Lambed Tatah, Monica Muti, Kim R. van Daalen, Trish Muzenda, Rachel Boscott, Omar Uwais, George Farmer, Adelaide Yue, Sarah Dalzell, Gudani Mukoma, Divya Bhagtani, Sostina Matina, Philip M. Dambisya, Kufre Okop, Charles Ebikeme, Lisa Micklesfield, Tolu Oni

“…A synthesised framework of seven interconnected components showcases an ecosystem on multisectoral interventions for urban health that can be examined in the future research in African urban settings that can benefit the health of people and the planet. Paper Context Main findings: Multisectoral interventions were identified in 27.8% of African countries in the African Union, targeted at major cities with five sectors present at all intervention stages: academia or research, agriculture, government, health, and non-governmental. …”
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Analisis Dampak Kabut Asap dari Kebakaran Hutan dan Lahan dengan Pendekatan Text Mining by Zuliar Efendi, Imas Sukaesih Sitanggang, Lailan Syaufina

“…The impact felt by the people of Riau Province through social media Twitter related to the haze is the impact on health and air quality. …”
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Race as a prognostic factor of breast mucinous carcinoma by Dingyuan Wang, Yang Wang, Songlin Gao, Rongshou Zheng, Guijian Wu, Jianping Wang, Can Lu, Kena Bu, Chun Zhang, Wanqing Chen, Bailin Zhang

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A PEDAGOGIA DA ALTERNÂNCIA COMO PROPOSTA DE EDUCAÇÃO NO CAMPO: UM ESTUDO NA ESCOLA FAMÍLIA AGRÍCOLA ITAPIREMA EM RONDÔNIA, BRASIL by Claudineia Ferreira dos Santos, Charles Carminati de Lima, Yanet Reimondo Barrios, Daniete Fernandes Rocha

“…This study evidences the contributions of the Alternation Pedagogy in the educational and social formation of young people living in a rural area in the State of Rondônia. …”
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A Community-Based Intervention for Mental Health and Wellbeing in Pregnancy and Postpartum: One Healthy Start Site’s Story by Sampson M, Xu W, York FN, Roberson J

“…McClain Sampson,1 Wen Xu,2 Felicia N York,3 Jerry Roberson4 1Graduate College of Social Work, University of Houston, Houston, TX, USA; 2Department of Innovative Social Work, Faculty of Health and Wellbeing, City University of Macau, Macao, SAR, People’s Republic of China; 3Texas A&M University, College Station, TX, USA; 4United Associates, Dallas, TX, USACorrespondence: McClain Sampson, Graduate College of Social Work, University of Houston, Houston, TX, USA, Email mmsampson@uh.eduPurpose: Perinatal mood and anxiety disorders (PMADs) are the leading cause for maternal morbidity and are associated with underlying causes of pregnancy-related death. …”
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Nature, prevalence and determinants of mental health problems experienced by adolescents in south Asia: a systematic reviewResearch in context by Chethana Mudunna, Medhavi Weerasinghe, Thach Tran, Josefine Antoniades, Lorena Romero, Miyuru Chandradasa, Jane Fisher

“…Most of the world's young people live in LMICs. This systematic review aims to assess the available evidence on the nature, prevalence and determinants of MHPs experienced by adolescents in south Asia. …”
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Call to Action: Lead Pharmacy into the Next Decade by Kerry K Fierke, Gardner Lepp, Bridget McGugan, Marta Brooks, Gregory Zumach

“…Traditional written manuscripts are valuable but may not fully connect with some people. The evolving landscape of healthcare leadership demands novel perspectives, creative applications, and open-minded evaluations. …”
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Association of social frailty, sarcopenia, and oral frailty with depressive symptoms in Chinese older adults: a cross-sectional study by Yuanhao Sun, Huan Liu, Xiangdong Li, Lin Zhang, Wenwen Xu, Hairong liu, Ting Yuan

“…Abstract Background Depressive symptoms are a serious health issue that can cause profound, lifelong suffering for people who are affected by it. This study aimed to evaluate the effect of sarcopenia, oral frailty, and social frailty on depressive symptoms among Chinese participants aged ≥ 60 years old in China. …”
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Realising health justice in Palestine: beyond humanitarian voices by James Smith, Sara el-Solh, Layth Hanbali, Sawsan Abdulrahim, Sali Hafez, Samer Abuzerr, Bram Wispelwey, Mads Gilbert, Mohammed Seyam, Bassam Abu Hamad, Dorotea Gucciardo, Fahd Haddad, Rasha Khoury, Amira Nimerawi, David Mills, Ghassan Abu-Sittah

“…Instead, we call for the collective practice of critical advocacy, solidarity with people affected by injustice and oppression, and an emancipatory politics in pursuit of justice in Palestine.…”
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Which patients received a ReSPECT form, what was documented and what were the patient outcomes? A protocol for a retrospective observational study investigating the impact of the C... by Lucy Selman, Charlotte Chamberlain, Adam McDermott, Claire A Woodall, Lucy Victoria Pocock

“…Data will be exported from the CCG Public Health Management data resource, a pseudonymised database linking data from organisations providing health and social care to people across BNSSG. Descriptive statistics of sociodemographic and health-related variables for those who completed the ReSPECT process with a clinician and had a documented ReSPECT form in their notes, in addition to their ReSPECT form responses, will be compared between before, during and after first COVID-19 wave groups. …”
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Peri‐ictal yawning: A potential lateralizing sign in temporal lobe epilepsy by Xiaoping Du, Yi Yao, Jiani Chen, Xiaoping Yang, Lei Zhang, Yingying Tang, Xiaoting Hao, Dong Zhou, Shizhong Lian, Fengpeng Wang, Xiaobin Zhang, Meizhen Sun, Junhong Guo

“…Abstract Objective The primary objective of this retrospective analysis was to evaluate the incidence and lateralization value of peri‐ictal yawning (PY) in people with temporal lobe epilepsy (TLE). PY has only occasionally been reported as a manifestation of focal epilepsy. …”
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Enhancement of CD8+T cell cytotoxicity activity by IFN-α implies alternative pathologic role in systemic lupus erythematosus by Chen-xing Zhang, You-ying Mao, Yu-pin Tan, Mei-yu Zhang, Kang Shao, Shu-jun Wang, Ping Ji, Jia-yuan Wang, Lei Yin, Ying Wang

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Implementasi Data Mining untuk Deteksi Penyakit Ginjal Kronis (PGK) menggunakan K-Nearest Neighbor (KNN) dengan Backward Elimination by Ikhsan Wisnuadji Gamadarenda, Indra Waspada

“…Abstract Chronic kidney disease (CKD) is a health problem for people around the world with increasing incidence. …”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

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Consumer Anthropomorphism and Happiness: Analysis of the Brand Authenticity Effect by Mehdi Khademi Gerashi, Setare Mohammadian

“…The process of anthropomorphism refers to the special desire of humans to attribute human characteristics to non-human beings, which can provide a basis for greater satisfaction. Given that people naturally tend to attribute human characteristics to beings, objects, and phenomena, and many researchers consider this tendency an essential tool for comprehending factors beyond human nature, it can serve as a foundation for enhancing customer satisfaction. …”
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Preference for HIV testing among community residents in Yunnan Province, China: results from a discrete choice experiment by Jingwen Yang, Chenquan Qiu, Renhai Tang, Wenbin Dong, Enlong Yao, Huyunzhao Wang, Shuwen Lin, Minyang Xiao, Zuyang Zhang, Jin Niu, Liru Fu, Lijun Song, Xuehua Li, Yuhua Shi, Xiaowen Wang

“…Abstract Background The detection and early identification of people living with HIV/AIDS (PLWH) and their rapid engagement in antiretroviral treatment are indispensable for fighting HIV transmission. …”
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Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis by Jiaqi Yao, Yuhong Jiang, Pengcheng Zhang, Yifan Miao, Xiajia Wu, Hang Lei, Zhijun Xie, Yong Tian, Xianlin Zhao, Juan Li, Lv Zhu, Meihua Wan, Wenfu Tang

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